STRINGSTRING
LOC100352102 LOC100352102 ENSOCUP00000044284 ENSOCUP00000044284 NR4A2 NR4A2 ENSOCUP00000037329 ENSOCUP00000037329 LOC103345451 LOC103345451 PTHLH PTHLH NRF1 NRF1 CDH2 CDH2 SNAI1 SNAI1 ZEB2 ZEB2 G1TC56_RABIT G1TC56_RABIT RARS1 RARS1 FOXO1 FOXO1 MYC MYC SNAI2 SNAI2 VIM VIM FOXA2 FOXA2 ZEB1 ZEB1 GPX1 GPX1 KLF4 KLF4 TGFB2 TGFB2 ESR1 ESR1 INHBA INHBA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100352102Uncharacterized protein. (256 aa)
ENSOCUP00000044284TGFb_propeptide domain-containing protein. (260 aa)
NR4A2Nuclear receptor subfamily 4 group A member 2. (609 aa)
ENSOCUP00000037329TGFb_propeptide domain-containing protein. (263 aa)
LOC103345451TGFb_propeptide domain-containing protein. (203 aa)
PTHLHParathyroid hormone-related protein; Neuroendocrine peptide which is a critical regulator of cellular and organ growth, development, migration, differentiation and survival and of epithelial calcium ion transport. Regulates endochondral bone development and epithelial-mesenchymal interactions during the formation of the mammary glands and teeth. Required for skeletal homeostasis. Promotes mammary mesenchyme differentiation and bud outgrowth by modulating mesenchymal cell responsiveness to BMPs. Upregulates BMPR1A expression in the mammary mesenchyme and this increases the sensitivity o [...] (220 aa)
NRF1Nuclear respiratory factor 1. (503 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (854 aa)
SNAI1Snail family transcriptional repressor 1. (238 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1188 aa)
G1TC56_RABITTGFb_propeptide domain-containing protein. (168 aa)
RARS1Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (660 aa)
FOXO1Fork-head domain-containing protein. (613 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa)
SNAI2Uncharacterized protein. (268 aa)
VIMVimentin; Belongs to the intermediate filament family. (466 aa)
FOXA2Forkhead box A2. (471 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1080 aa)
GPX1Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. (200 aa)
KLF4Uncharacterized protein. (145 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
ESR1Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (598 aa)
INHBAInhibin subunit beta A. (424 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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