(35 nodes) (2022) NOS1AP is a novel molecular target and critical factor in TDP-43 pathology. network (Oryctolagus cuniculus)

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	STX1A	Syntaxin 1A; Belongs to the syntaxin family. (315 aa)
	HNRNPD	Heterogeneous nuclear ribonucleoprotein D. (286 aa)
	RPL32	Uncharacterized protein. (135 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (592 aa)
	POLA2	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (600 aa)
	HNRNPR	Heterogeneous nuclear ribonucleoprotein R. (635 aa)
	OPHN1	Oligophrenin 1. (775 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (404 aa)
	CPE	Uncharacterized protein. (472 aa)
	HNRNPK	Heterogeneous nuclear ribonucleoprotein K; One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction. As far as transcription repression is co [...] (463 aa)
	SEMA3F	Semaphorin 3F; Belongs to the semaphorin family. (784 aa)
	SYT14	Uncharacterized protein. (1058 aa)
	APOA2	Apolipoprotein A2. (100 aa)
	SORT1	Sortilin. (800 aa)
	G1TJG6_RABIT	Glyceraldehyde-3-phosphate dehydrogenase. (305 aa)
	SYNCRIP	Uncharacterized protein. (623 aa)
	GRIN2D	Glutamate ionotropic receptor NMDA type subunit 2D. (888 aa)
	RPL13A	Uncharacterized protein. (135 aa)
	MATR3	Uncharacterized protein. (847 aa)
	G1TYG1_RABIT	Glyceraldehyde-3-phosphate dehydrogenase. (369 aa)
	LLGL2	LLGL scribble cell polarity complex component 2. (1009 aa)
	HNRNPL	Heterogeneous nuclear ribonucleoprotein L; Belongs to the enoyl-CoA hydratase/isomerase family. (763 aa)
	NOS3	Nitric oxide synthase; Produces nitric oxide (NO). (1209 aa)
	U3KN68_RABIT	Uncharacterized protein. (386 aa)
	ENSOCUP00000027714	Uncharacterized protein. (229 aa)
	STMN2	Stathmin; Belongs to the stathmin family. (184 aa)
	UBE2E3	UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (465 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (346 aa)
	STX3-2	SynN domain-containing protein. (271 aa)
	STX3	Syntaxin 3; Belongs to the syntaxin family. (264 aa)
	SNCA	Alpha-synuclein; Belongs to the synuclein family. (172 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
	DEPTOR	DEP domain containing MTOR interacting protein. (498 aa)
	HNRNPU	Heterogeneous nuclear ribonucleoprotein U. (844 aa)
	MCM10	Minichromosome maintenance 10 replication initiation factor. (881 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDK2	G1TJG6_RABIT	ENSOCUP00000034758	ENSOCUP00000017094	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.685
CDK2	G1TYG1_RABIT	ENSOCUP00000034758	ENSOCUP00000022125	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase.	0.684
CDK2	GAPDH	ENSOCUP00000034758	ENSOCUP00000044112	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.859
CDK2	MCM10	ENSOCUP00000034758	ENSOCUP00000047051	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	Minichromosome maintenance 10 replication initiation factor.	0.772
CDK2	POLA2	ENSOCUP00000034758	ENSOCUP00000003956	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis.	0.533
CPE	ENSOCUP00000027714	ENSOCUP00000007068	ENSOCUP00000027714	Uncharacterized protein.	Uncharacterized protein.	0.901
CPE	SORT1	ENSOCUP00000007068	ENSOCUP00000011881	Uncharacterized protein.	Sortilin.	0.567
CPE	U3KN68_RABIT	ENSOCUP00000007068	ENSOCUP00000026677	Uncharacterized protein.	Uncharacterized protein.	0.900
CX3CL1	GAPDH	ENSOCUP00000006470	ENSOCUP00000044112	C-X3-C motif chemokine ligand 1.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.480
CX3CL1	RPL13A	ENSOCUP00000006470	ENSOCUP00000021167	C-X3-C motif chemokine ligand 1.	Uncharacterized protein.	0.454
ENSOCUP00000027714	CPE	ENSOCUP00000027714	ENSOCUP00000007068	Uncharacterized protein.	Uncharacterized protein.	0.901
ENSOCUP00000027714	SORT1	ENSOCUP00000027714	ENSOCUP00000011881	Uncharacterized protein.	Sortilin.	0.612
ENSOCUP00000027714	U3KN68_RABIT	ENSOCUP00000027714	ENSOCUP00000026677	Uncharacterized protein.	Uncharacterized protein.	0.900
G1TJG6_RABIT	CDK2	ENSOCUP00000017094	ENSOCUP00000034758	Glyceraldehyde-3-phosphate dehydrogenase.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.685
G1TJG6_RABIT	RPL13A	ENSOCUP00000017094	ENSOCUP00000021167	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.989
G1TJG6_RABIT	SNCA	ENSOCUP00000017094	ENSOCUP00000039624	Glyceraldehyde-3-phosphate dehydrogenase.	Alpha-synuclein; Belongs to the synuclein family.	0.421
G1TJG6_RABIT	SYNCRIP	ENSOCUP00000017094	ENSOCUP00000017167	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.480
G1TYG1_RABIT	CDK2	ENSOCUP00000022125	ENSOCUP00000034758	Glyceraldehyde-3-phosphate dehydrogenase.	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily.	0.684
G1TYG1_RABIT	RPL13A	ENSOCUP00000022125	ENSOCUP00000021167	Glyceraldehyde-3-phosphate dehydrogenase.	Uncharacterized protein.	0.989
G1TYG1_RABIT	SNCA	ENSOCUP00000022125	ENSOCUP00000039624	Glyceraldehyde-3-phosphate dehydrogenase.	Alpha-synuclein; Belongs to the synuclein family.	0.408