30 items (Oryctolagus cuniculus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTB	Uncharacterized protein. (357 aa)
	CBLN4	Cerebellin 4 precursor. (201 aa)
	DAG1	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...] (895 aa)
	LRRTM3	Leucine rich repeat transmembrane neuronal 3. (581 aa)
	CBLN2	C1q domain-containing protein. (115 aa)
	NLGN2	Neuroligin 2. (823 aa)
	AQP4	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (323 aa)
	NRXN2	Neurexin 2. (924 aa)
	HOMER1	Homer scaffold protein 1. (354 aa)
	GRID2	Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
	NXPH1	Neurexophilin; May be signaling molecules that resemble neuropeptides. (271 aa)
	NXPH3	Neurexophilin; May be signaling molecules that resemble neuropeptides. (234 aa)
	DMD	Uncharacterized protein. (956 aa)
	EGF	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa)
	INS	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (164 aa)
	NLGN3	Neuroligin 3. (828 aa)
	LRRTM2	Leucine rich repeat transmembrane neuronal 2. (516 aa)
	NXPH2	Neurexophilin; May be signaling molecules that resemble neuropeptides. (266 aa)
	LRRTM1	Leucine rich repeat transmembrane neuronal 1. (574 aa)
	TAFA4	TAFA chemokine like family member 4. (201 aa)
	NRXN3	Neurexin 3. (1664 aa)
	NRXN1	Neurexin 1. (1507 aa)
	SYNPR	Synaptoporin. (285 aa)
	LRRTM4	Leucine rich repeat transmembrane neuronal 4. (591 aa)
	GPHN	Molybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (750 aa)
	TAFA1	TAFA chemokine like family member 1. (133 aa)
	TAFA2	TAFA chemokine like family member 2. (187 aa)
	GAPDH	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa)
	NLGN1	Neuroligin 1. (823 aa)
	CBLN1	Cerebellin 1 precursor. (254 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTB	DMD	ENSOCUP00000045964	ENSOCUP00000013070	Uncharacterized protein.	Uncharacterized protein.	0.924
ACTB	EGF	ENSOCUP00000045964	ENSOCUP00000014095	Uncharacterized protein.	Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.	0.592
ACTB	GAPDH	ENSOCUP00000045964	ENSOCUP00000044112	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.891
ACTB	INS	ENSOCUP00000045964	ENSOCUP00000020463	Uncharacterized protein.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.659
AQP4	DAG1	ENSOCUP00000007625	ENSOCUP00000002981	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Alpha-dystroglycan; The dystroglycan complex is involved in a number of processes including laminin and basement membrane assembly, sacrolemmal stability, cell survival, peripheral nerve myelination, nodal structure, cell migration, and epithelial polarization. Beta-dystroglycan is a transmembrane protein that plays important roles in connecting the extracellular matrix to the cytoskeleton. Acts as a cell adhesion receptor in both muscle and non- muscle tissues. Receptor for both DMD and UTRN and, through these interactions, scaffolds axin to the cytoskeleton. Also functions in cell ad [...]	0.721
AQP4	DMD	ENSOCUP00000007625	ENSOCUP00000013070	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Uncharacterized protein.	0.829
AQP4	GAPDH	ENSOCUP00000007625	ENSOCUP00000044112	Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family.	Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...]	0.592
CBLN1	GRID2	ENSOCUP00000045776	ENSOCUP00000009838	Cerebellin 1 precursor.	Glutamate ionotropic receptor delta type subunit 2.	0.864
CBLN1	LRRTM1	ENSOCUP00000045776	ENSOCUP00000027450	Cerebellin 1 precursor.	Leucine rich repeat transmembrane neuronal 1.	0.631
CBLN1	LRRTM2	ENSOCUP00000045776	ENSOCUP00000022777	Cerebellin 1 precursor.	Leucine rich repeat transmembrane neuronal 2.	0.666
CBLN1	NLGN1	ENSOCUP00000045776	ENSOCUP00000044921	Cerebellin 1 precursor.	Neuroligin 1.	0.426
CBLN1	NRXN1	ENSOCUP00000045776	ENSOCUP00000034839	Cerebellin 1 precursor.	Neurexin 1.	0.943
CBLN1	NRXN2	ENSOCUP00000045776	ENSOCUP00000008270	Cerebellin 1 precursor.	Neurexin 2.	0.673
CBLN2	GRID2	ENSOCUP00000003610	ENSOCUP00000009838	C1q domain-containing protein.	Glutamate ionotropic receptor delta type subunit 2.	0.681
CBLN2	LRRTM1	ENSOCUP00000003610	ENSOCUP00000027450	C1q domain-containing protein.	Leucine rich repeat transmembrane neuronal 1.	0.460
CBLN2	NLGN1	ENSOCUP00000003610	ENSOCUP00000044921	C1q domain-containing protein.	Neuroligin 1.	0.482
CBLN2	NLGN2	ENSOCUP00000003610	ENSOCUP00000004804	C1q domain-containing protein.	Neuroligin 2.	0.447
CBLN2	NLGN3	ENSOCUP00000003610	ENSOCUP00000022184	C1q domain-containing protein.	Neuroligin 3.	0.449
CBLN2	NRXN1	ENSOCUP00000003610	ENSOCUP00000034839	C1q domain-containing protein.	Neurexin 1.	0.682
CBLN4	GRID2	ENSOCUP00000000062	ENSOCUP00000009838	Cerebellin 4 precursor.	Glutamate ionotropic receptor delta type subunit 2.	0.465