STRINGSTRING
PCGF5 PCGF5 ENSOCUP00000042583 ENSOCUP00000042583 DLL1 DLL1 IL7 IL7 CD19 CD19 CTCF CTCF KIT KIT CSF1R CSF1R PCGF1 PCGF1 CD34 CD34 CD4 CD4 G1TJR7_RABIT G1TJR7_RABIT PCGF2 PCGF2 IL1B IL1B G1TX56_RABIT G1TX56_RABIT LOC100340625 LOC100340625 HOXA9 HOXA9 LOC100344410 LOC100344410 CEBPE CEBPE H3-3A H3-3A HPRT1 HPRT1 LOC100345683 LOC100345683 H3C13 H3C13 MPP3 MPP3 ATF3 ATF3 IRF8 IRF8 CSF2 CSF2 KDM2B KDM2B TET2 TET2 EBF1 EBF1 PAX5 PAX5 LOC100357927 LOC100357927 H3F3B H3F3B HOXA7 HOXA7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PCGF5Polycomb group ring finger 5. (256 aa)
ENSOCUP00000042583Histone H3; Belongs to the histone H3 family. (115 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (754 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
CD19CD19 molecule. (573 aa)
CTCFCCCTC-binding factor. (738 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (973 aa)
PCGF1Polycomb group ring finger 1. (263 aa)
CD34CD34 molecule. (415 aa)
CD4T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...] (536 aa)
G1TJR7_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
PCGF2Polycomb group ring finger 2. (324 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa)
G1TX56_RABITHistone H3; Belongs to the histone H3 family. (136 aa)
LOC100340625ANK_REP_REGION domain-containing protein. (324 aa)
HOXA9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (276 aa)
LOC100344410Histone domain-containing protein. (136 aa)
CEBPECCAAT/enhancer-binding protein. (281 aa)
H3-3AHistone H3.3; Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in [...] (136 aa)
HPRT1Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (218 aa)
LOC100345683Histone H3; Belongs to the histone H3 family. (136 aa)
H3C13Histone H3; Belongs to the histone H3 family. (136 aa)
MPP3Membrane palmitoylated protein 3; Belongs to the MAGUK family. (584 aa)
ATF3Activating transcription factor 3. (207 aa)
IRF8Interferon regulatory factor 8. (455 aa)
CSF2Uncharacterized protein. (144 aa)
KDM2BLysine demethylase 2B. (1341 aa)
TET2Tet methylcytosine dioxygenase 2. (2011 aa)
EBF1EBF transcription factor 1. (591 aa)
PAX5Paired box 5. (371 aa)
LOC100357927Histone domain-containing protein. (136 aa)
H3F3BHistone H3; Belongs to the histone H3 family. (136 aa)
HOXA7Homeobox domain-containing protein. (234 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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