node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCR7 | CD163 | ENSOCUP00000017477 | ENSOCUP00000041329 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | CD163 molecule. | 0.740 |
CCR7 | IL1B | ENSOCUP00000017477 | ENSOCUP00000021869 | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.734 |
CD163 | CCR7 | ENSOCUP00000041329 | ENSOCUP00000017477 | CD163 molecule. | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | 0.740 |
CD163 | IL1B | ENSOCUP00000041329 | ENSOCUP00000021869 | CD163 molecule. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.819 |
ENSOCUP00000037329 | ENSOCUP00000044284 | ENSOCUP00000037329 | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.412 |
ENSOCUP00000037329 | G1TC56_RABIT | ENSOCUP00000037329 | ENSOCUP00000014344 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.429 |
ENSOCUP00000037329 | IL1B | ENSOCUP00000037329 | ENSOCUP00000021869 | TGFb_propeptide domain-containing protein. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.814 |
ENSOCUP00000037329 | LOC103345451 | ENSOCUP00000037329 | ENSOCUP00000031740 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.419 |
ENSOCUP00000037329 | TGFB3 | ENSOCUP00000037329 | ENSOCUP00000009817 | TGFb_propeptide domain-containing protein. | Transforming growth factor beta 3. | 0.482 |
ENSOCUP00000044284 | ENSOCUP00000037329 | ENSOCUP00000044284 | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.412 |
ENSOCUP00000044284 | G1TC56_RABIT | ENSOCUP00000044284 | ENSOCUP00000014344 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.543 |
ENSOCUP00000044284 | IL1B | ENSOCUP00000044284 | ENSOCUP00000021869 | TGFb_propeptide domain-containing protein. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.814 |
ENSOCUP00000044284 | TGFB3 | ENSOCUP00000044284 | ENSOCUP00000009817 | TGFb_propeptide domain-containing protein. | Transforming growth factor beta 3. | 0.589 |
G1TC56_RABIT | ENSOCUP00000037329 | ENSOCUP00000014344 | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.429 |
G1TC56_RABIT | ENSOCUP00000044284 | ENSOCUP00000014344 | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. | TGFb_propeptide domain-containing protein. | 0.543 |
G1TC56_RABIT | IL1B | ENSOCUP00000014344 | ENSOCUP00000021869 | TGFb_propeptide domain-containing protein. | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | 0.762 |
IL1B | CCR7 | ENSOCUP00000021869 | ENSOCUP00000017477 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. | 0.734 |
IL1B | CD163 | ENSOCUP00000021869 | ENSOCUP00000041329 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | CD163 molecule. | 0.819 |
IL1B | ENSOCUP00000037329 | ENSOCUP00000021869 | ENSOCUP00000037329 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | TGFb_propeptide domain-containing protein. | 0.814 |
IL1B | ENSOCUP00000044284 | ENSOCUP00000021869 | ENSOCUP00000044284 | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. | TGFb_propeptide domain-containing protein. | 0.814 |