17 items (Oryctolagus cuniculus) - STRING interaction network

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Your Input:
	IL7	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (175 aa)
	LYN	Tyrosine-protein kinase. (636 aa)
	PXDNL	Peroxidasin like. (1467 aa)
	BTK	Tyrosine-protein kinase. (659 aa)
	PAX5	Paired box 5. (371 aa)
	FYN	Tyrosine-protein kinase. (537 aa)
	SYK	Tyrosine-protein kinase. (630 aa)
	IGLL1	Lambda5. (208 aa)
	IGHM-2	Ig-like domain-containing protein. (167 aa)
	RAG1	V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1128 aa)
	RAG2	V(D)J recombination-activating protein 2; Core component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T- cell receptor genes in developing B and T-lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. DNA cleavage by the RAG complex occurs in 2 steps: a first nick is introduced in the top strand immediately upstream of the heptamer, generating a 3'-hydroxyl group that can attack the pho [...] (527 aa)
	PXDN	Peroxidasin. (1411 aa)
	IL4	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...] (144 aa)
	IGHM-3	Ig-like domain-containing protein. (167 aa)
	CD40	Uncharacterized protein. (494 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (970 aa)
	BCL2	BH4_2 domain-containing protein. (389 aa)

Your Current Organism:

Oryctolagus cuniculus

NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BCL2	BTK	ENSOCUP00000036189	ENSOCUP00000009153	BH4_2 domain-containing protein.	Tyrosine-protein kinase.	0.472
BCL2	CD40	ENSOCUP00000036189	ENSOCUP00000034264	BH4_2 domain-containing protein.	Uncharacterized protein.	0.630
BCL2	IGHM-2	ENSOCUP00000036189	ENSOCUP00000018495	BH4_2 domain-containing protein.	Ig-like domain-containing protein.	0.650
BCL2	IGHM-3	ENSOCUP00000036189	ENSOCUP00000025645	BH4_2 domain-containing protein.	Ig-like domain-containing protein.	0.650
BCL2	IL4	ENSOCUP00000036189	ENSOCUP00000025135	BH4_2 domain-containing protein.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.653
BCL2	IL7	ENSOCUP00000036189	ENSOCUP00000038193	BH4_2 domain-containing protein.	Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family.	0.653
BCL2	KIT	ENSOCUP00000036189	ENSOCUP00000034895	BH4_2 domain-containing protein.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.662
BCL2	PAX5	ENSOCUP00000036189	ENSOCUP00000010574	BH4_2 domain-containing protein.	Paired box 5.	0.541
BCL2	PXDN	ENSOCUP00000036189	ENSOCUP00000022906	BH4_2 domain-containing protein.	Peroxidasin.	0.911
BCL2	PXDNL	ENSOCUP00000036189	ENSOCUP00000004823	BH4_2 domain-containing protein.	Peroxidasin like.	0.911
BCL2	SYK	ENSOCUP00000036189	ENSOCUP00000015068	BH4_2 domain-containing protein.	Tyrosine-protein kinase.	0.459
BTK	BCL2	ENSOCUP00000009153	ENSOCUP00000036189	Tyrosine-protein kinase.	BH4_2 domain-containing protein.	0.472
BTK	CD40	ENSOCUP00000009153	ENSOCUP00000034264	Tyrosine-protein kinase.	Uncharacterized protein.	0.593
BTK	FYN	ENSOCUP00000009153	ENSOCUP00000013559	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.557
BTK	IGHM-2	ENSOCUP00000009153	ENSOCUP00000018495	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.538
BTK	IGHM-3	ENSOCUP00000009153	ENSOCUP00000025645	Tyrosine-protein kinase.	Ig-like domain-containing protein.	0.545
BTK	IGLL1	ENSOCUP00000009153	ENSOCUP00000015640	Tyrosine-protein kinase.	Lambda5.	0.651
BTK	IL4	ENSOCUP00000009153	ENSOCUP00000025135	Tyrosine-protein kinase.	Interleukin-4; Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4; Belongs to the IL- [...]	0.451
BTK	KIT	ENSOCUP00000009153	ENSOCUP00000034895	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.479
BTK	LYN	ENSOCUP00000009153	ENSOCUP00000002661	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.984