STRINGSTRING
SOCS4 SOCS4 SH3BP2 SH3BP2 JAK2 JAK2 SYK SYK BMX BMX CISH CISH PLCG1 PLCG1 SH2D5 SH2D5 SH2D3C SH2D3C GRB7 GRB7 VAV1 VAV1 SH2B1 SH2B1 NCK2 NCK2 VAV3 VAV3 TYK2 TYK2 FER FER INPP5D INPP5D TNS1 TNS1 STAT5A STAT5A SH2B2 SH2B2 SH2D1A SH2D1A FES FES BLK BLK SH2D2A SH2D2A TNS4 TNS4 ITK ITK HSH2D HSH2D SOCS2 SOCS2 FRK FRK LCK LCK ABL1 ABL1 CLNK CLNK LYN LYN GRB14 GRB14 SLA2 SLA2 SH2B3 SH2B3 RASA1 RASA1 YWHAE YWHAE CHN1 CHN1 SRC SRC GRB2 GRB2 SHF SHF PTPN6 PTPN6 SHC3 SHC3 STAT1 STAT1 SOCS6 SOCS6 STAT5B STAT5B PIK3R1 PIK3R1 CBLB CBLB RIN3 RIN3 ZAP70 ZAP70 YES1 YES1 JAK1 JAK1 SHC4 SHC4 TXK TXK TEC TEC NCK1 NCK1 STAT6 STAT6 STAP1 STAP1 ABL2 ABL2 FGR FGR HCK HCK PTPN11 PTPN11 STAT4 STAT4 SLA SLA SHB SHB SH2D1B SH2D1B BTK BTK STAT3 STAT3 GRAP2 GRAP2 PLCG2 PLCG2 LOC100345250 LOC100345250 GRB10 GRB10 BCAR3 BCAR3 RIN2 RIN2 SH2D4B SH2D4B SOCS7 SOCS7 FYN FYN GRAP GRAP SHC1 SHC1 SHE SHE SH2D4A SH2D4A LCP2 LCP2 CRKL CRKL SUPT6H SUPT6H DAPP1 DAPP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS4Suppressor of cytokine signaling 4. (441 aa)
SH3BP2SH3 domain binding protein 2. (556 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
SYKTyrosine-protein kinase. (630 aa)
BMXTyrosine-protein kinase. (655 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa)
SH2D5SH2 domain containing 5. (421 aa)
SH2D3CSH2 domain-containing protein. (580 aa)
GRB7Growth factor receptor bound protein 7. (529 aa)
VAV1Vav guanine nucleotide exchange factor 1. (681 aa)
SH2B1SH2 domain-containing protein. (337 aa)
NCK2Cytoplasmic protein. (380 aa)
VAV3Vav guanine nucleotide exchange factor 3. (964 aa)
TYK2Non-specific protein-tyrosine kinase. (1065 aa)
FERTyrosine-protein kinase. (452 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (910 aa)
TNS1Tensin 1. (1773 aa)
STAT5ASignal transducer and activator of transcription. (793 aa)
SH2B2SH2B adaptor protein 2. (625 aa)
SH2D1ASH2 domain containing 1A. (132 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (857 aa)
BLKTyrosine-protein kinase. (525 aa)
SH2D2ASH2 domain-containing protein. (667 aa)
TNS4Tensin 4. (722 aa)
ITKTyrosine-protein kinase. (611 aa)
HSH2DHematopoietic SH2 domain containing. (335 aa)
SOCS2Suppressor of cytokine signaling 2. (307 aa)
FRKFyn related Src family tyrosine kinase. (389 aa)
LCKTyrosine-protein kinase. (637 aa)
ABL1Tyrosine-protein kinase. (1118 aa)
CLNKCytokine dependent hematopoietic cell linker. (430 aa)
LYNTyrosine-protein kinase. (636 aa)
GRB14Growth factor receptor bound protein 14. (540 aa)
SLA2Src like adaptor 2. (277 aa)
SH2B3SH2B adaptor protein 3. (354 aa)
RASA1RAS p21 protein activator 1. (967 aa)
YWHAETyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (436 aa)
CHN1Chimerin 1. (531 aa)
SRCTyrosine-protein kinase. (589 aa)
GRB2Growth factor receptor bound protein 2. (278 aa)
SHFSrc homology 2 domain containing F. (267 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (561 aa)
SHC3SHC adaptor protein 3. (458 aa)
STAT1Signal transducer and activator of transcription. (879 aa)
SOCS6Suppressor of cytokine signaling 6. (512 aa)
STAT5BSignal transducer and activator of transcription. (786 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CBLBCbl proto-oncogene B. (983 aa)
RIN3Ras and Rab interactor 3. (941 aa)
ZAP70Tyrosine-protein kinase. (623 aa)
YES1Tyrosine-protein kinase. (543 aa)
JAK1Tyrosine-protein kinase. (1151 aa)
SHC4SHC adaptor protein 4. (630 aa)
TXKTyrosine-protein kinase. (556 aa)
TECTyrosine-protein kinase. (631 aa)
NCK1Cytoplasmic protein. (377 aa)
STAT6Signal transducer and activator of transcription. (842 aa)
STAP1Signal transducing adaptor family member 1. (273 aa)
ABL2Tyrosine-protein kinase. (1146 aa)
FGRTyrosine-protein kinase. (527 aa)
HCKTyrosine-protein kinase. (525 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
STAT4Signal transducer and activator of transcription. (752 aa)
SLASrc like adaptor. (315 aa)
SHBSH2 domain-containing protein. (607 aa)
SH2D1BUncharacterized protein. (174 aa)
BTKTyrosine-protein kinase. (659 aa)
STAT3Signal transducer and activator of transcription. (770 aa)
GRAP2GRB2 related adaptor protein 2. (267 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
LOC100345250Uncharacterized protein. (461 aa)
GRB10Growth factor receptor bound protein 10. (550 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (827 aa)
RIN2Ras and Rab interactor 2. (895 aa)
SH2D4BSH2 domain containing 4B. (431 aa)
SOCS7Suppressor of cytokine signaling 7. (583 aa)
FYNTyrosine-protein kinase. (537 aa)
GRAPGRB2 related adaptor protein. (342 aa)
SHC1SHC adaptor protein 1. (474 aa)
SHESrc homology 2 domain containing E. (499 aa)
SH2D4ASH2 domain containing 4A. (450 aa)
LCP2Lymphocyte cytosolic protein 2. (534 aa)
CRKLCRK like proto-oncogene, adaptor protein. (303 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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