STRINGSTRING
CCK CCK HTR2C HTR2C NPFFR1 NPFFR1 ADRB2 ADRB2 CYSLTR1 CYSLTR1 GABBR2 GABBR2 CHRM2 CHRM2 HTR5BP HTR5BP GRM6 GRM6 GNRHR GNRHR UCN UCN P2RY4 P2RY4 LEPR LEPR GRM7 GRM7 TAAR1 TAAR1 GRM2 GRM2 GLRA3 GLRA3 LOC100355300 LOC100355300 EDNRB EDNRB PTAFR PTAFR NMB NMB LOC100346200 LOC100346200 GALR3 GALR3 GRIA2 GRIA2 TAAR6 TAAR6 G1TGW5_RABIT G1TGW5_RABIT HTR1B HTR1B FSHB FSHB GABRR3 GABRR3 GABRG1 GABRG1 LTB4R2 LTB4R2 HRH4 HRH4 ADORA3 ADORA3 LOC100344665 LOC100344665 MC3R MC3R AVPR1A AVPR1A Tshb Tshb SSTR1 SSTR1 CYSLTR2 CYSLTR2 HTR1F HTR1F LOC100340278 LOC100340278 PRLH PRLH ADRA2B ADRA2B APLNR APLNR NPBWR1 NPBWR1 GCG GCG TAC4 TAC4 NPY2R NPY2R PTGIR PTGIR TAAR5 TAAR5 CHRNA5 CHRNA5 CORT CORT F2R F2R MC5R MC5R BRS3 BRS3 P2RX5 P2RX5 GHRL GHRL GABRD GABRD PRLR PRLR MGRA MGRA OPRM1 OPRM1 AVPR2 AVPR2 THRA THRA KNG1 KNG1 GHR GHR GRIK1 GRIK1 CRHR1 CRHR1 CHRNA4 CHRNA4 NPY5R NPY5R CHRNA6 CHRNA6 OPRK1 OPRK1 HRH2 HRH2 GRIN2A GRIN2A POMC POMC S1PR2 S1PR2 VIPR1 VIPR1 CRHR2 CRHR2 KISS1 KISS1 GLP2R GLP2R GRIA1 GRIA1 GABRB2 GABRB2 GRM8 GRM8 HTR1E HTR1E GRIA4 GRIA4 PRSS2 PRSS2 CALCB CALCB PRLHR PRLHR TSPO TSPO S1PR5 S1PR5 AVP AVP FPR2 FPR2 OXT OXT EDN3 EDN3 NR3C1 NR3C1 HTR7 HTR7 PTGER3 PTGER3 CRH CRH PARD3 PARD3 ENSOCUP00000047896 ENSOCUP00000047896 HTR4 HTR4 GABBR1 GABBR1 GRIA3 GRIA3 P2RY13 P2RY13 AGT AGT VIP VIP PTGER4 PTGER4 GABRR1 GABRR1 GABRR2 GABRR2 TACR1 TACR1 OPRD1 OPRD1 EDN2 EDN2 EDNRA EDNRA PRL PRL TSHR TSHR PLG PLG NMBR NMBR P2RX4 P2RX4 LPAR6 LPAR6 GRM4 GRM4 PTGFR PTGFR F2RL1 F2RL1 CHRNA7 CHRNA7 GLRA1 GLRA1 GRIK4 GRIK4 PMCH PMCH PTGDR PTGDR VIPR2 VIPR2 GABRB3 GABRB3 TRHR TRHR GRIK2 GRIK2 GH1 GH1 GIP GIP GLRB GLRB INSL5 INSL5 DRD1 DRD1 RXFP3 RXFP3 CHRNA3 CHRNA3 CHRNB3 CHRNB3 PDYN PDYN PTH PTH GRIK3 GRIK3 C5 C5 HCRTR1 HCRTR1 GHRH GHRH P2RY14 P2RY14 TRH TRH GPR156 GPR156 LOC100354791 LOC100354791 NPFFR2 NPFFR2 GRM1 GRM1 UTS2B UTS2B LOC100344381 LOC100344381 GHSR GHSR AVPR1B AVPR1B GRM3 GRM3 CHRNB1 CHRNB1 C3AR1 C3AR1 SST SST TAAR2 TAAR2 CHRNA2 CHRNA2 SCTR SCTR HCRTR2 HCRTR2 CCKBR CCKBR GABRQ GABRQ GABRP GABRP MTNR1B MTNR1B TAAR9 TAAR9 CGA CGA GABRA3 GABRA3 FPR1 FPR1 ADORA2A ADORA2A P2RX7 P2RX7 GRP GRP SSTR2 SSTR2 ADCYAP1 ADCYAP1 TACR3 TACR3 GABRE GABRE HTR1A HTR1A ADM ADM NPY1R NPY1R HTR2A HTR2A LEP LEP CHRNE CHRNE NTS NTS NPY NPY ADORA1 ADORA1 HTR1D HTR1D FSHR FSHR GRID2 GRID2 GLRA2 GLRA2 GABRG3 GABRG3 TRPV1 TRPV1 AGTR2 AGTR2 PTGER2 PTGER2 GRM5 GRM5 GRID1 GRID1 GRPR GRPR GABRA5 GABRA5 PYY PYY HCRT HCRT EDN1 EDN1 RLN3 RLN3 CCKAR CCKAR NMUR2 NMUR2 UCN3 UCN3 CALCRL CALCRL GNRH1 GNRH1 NPY4R NPY4R P2RY10 P2RY10 P2RX6 P2RX6 MLNR MLNR BDKRB2 BDKRB2 GABRA6 GABRA6 GRIN2B GRIN2B LOC100346285 LOC100346285 S1PR3 S1PR3 GPR83 GPR83 GABRA1 GABRA1 CHRM4 CHRM4 RXFP2 RXFP2 LPAR1 LPAR1 BDKRB1 BDKRB1 CNR2 CNR2 P2RY8 P2RY8 MC4R MC4R LPAR3 LPAR3 PTH2 PTH2 MC2R MC2R ADRB3 ADRB3 RXFP4 RXFP4 G1TX71_RABIT G1TX71_RABIT GRIN2C GRIN2C LOC100355052 LOC100355052 CHRM5 CHRM5 CHRNA9 CHRNA9 CALCR CALCR C5AR1 C5AR1 CHRM3 CHRM3 GABRA4 GABRA4 MTNR1A MTNR1A ADORA2B ADORA2B LOC100345534 LOC100345534 GRIN3A GRIN3A NPY6R NPY6R P2RX1 P2RX1 NMUR1 NMUR1 LTB4R LTB4R RELH_RABIT RELH_RABIT P2RY1 P2RY1 GABRB1 GABRB1 DRD5 DRD5 NPFF NPFF PPY PPY TACR2 TACR2 LHB LHB CHRND CHRND DRD3 DRD3 P2RY11 P2RY11 TAAR4 TAAR4 HTR5A HTR5A ADRA1B ADRA1B LHCGR LHCGR ADRA1A ADRA1A P2RX3 P2RX3 AGTR1 AGTR1 TAC3 TAC3 LOC108178086 LOC108178086
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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CCKGastrin domain-containing protein. (115 aa)
HTR2C5-hydroxytryptamine receptor 2C. (453 aa)
NPFFR1Neuropeptide FF receptor 1; Belongs to the G-protein coupled receptor 1 family. (437 aa)
ADRB2Adrenoceptor beta 2. (437 aa)
CYSLTR1Cysteinyl leukotriene receptor 1. (340 aa)
GABBR2Gamma-aminobutyric acid type B receptor subunit 2. (880 aa)
CHRM2Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (520 aa)
HTR5BPG_PROTEIN_RECEP_F1_2 domain-containing protein. (371 aa)
GRM6Metabotropic glutamate receptor 6; G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity (By similarity). Signaling stimulates TRPM1 channel activity and Ca(2+) uptake. Required for normal vision. (867 aa)
GNRHRG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (328 aa)
UCNUrocortin. (128 aa)
P2RY4Pyrimidinergic receptor P2Y4; Belongs to the G-protein coupled receptor 1 family. (416 aa)
LEPRLeptin receptor. (1164 aa)
GRM7Glutamate metabotropic receptor 7. (677 aa)
TAAR1Trace amine associated receptor 1; Belongs to the G-protein coupled receptor 1 family. (325 aa)
GRM2Glutamate metabotropic receptor 2. (872 aa)
GLRA3Glycine receptor alpha 3; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
LOC100355300G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (342 aa)
EDNRBEndothelin receptor type B; Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRB sub-subfamily. (441 aa)
PTAFRPlatelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa)
NMBUncharacterized protein. (343 aa)
LOC100346200Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (264 aa)
GALR3Galanin receptor 3; Belongs to the G-protein coupled receptor 1 family. (367 aa)
GRIA2Glutamate ionotropic receptor AMPA type subunit 2. (883 aa)
TAAR6Trace amine associated receptor 6; Belongs to the G-protein coupled receptor 1 family. (344 aa)
G1TGW5_RABITG_PROTEIN_RECEP_F1_2 domain-containing protein. (367 aa)
HTR1B5-hydroxytryptamine receptor 1B; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopami [...] (389 aa)
FSHBFollitropin subunit beta; Together with the alpha chain CGA constitutes follitropin, the follicle-stimulating hormone, and provides its biological specificity to the hormone heterodimer. Binds FSHR, a G protein-coupled receptor, on target cells to activate downstream signaling pathways. Follitropin is involved in follicle development and spermatogenesis in reproductive organs. (129 aa)
GABRR3Gamma-aminobutyric acid type A receptor rho3 subunit (gene/pseudogene); Belongs to the ligand-gated ion channel (TC 1.A.9) family. (468 aa)
GABRG1Gamma-aminobutyric acid type A receptor gamma1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
LTB4R2Leukotriene B4 receptor 2. (343 aa)
HRH4Histamine receptor H4; Belongs to the G-protein coupled receptor 1 family. (384 aa)
ADORA3Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase. (319 aa)
LOC100344665G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
MC3RMelanocortin 3 receptor. (323 aa)
AVPR1AVasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (418 aa)
TshbThyroid-stimulating hormone beta subunit. (138 aa)
SSTR1Somatostatin receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
CYSLTR2G_PROTEIN_RECEP_F1_2 domain-containing protein. (355 aa)
HTR1F5-hydroxytryptamine receptor 1F. (366 aa)
LOC100340278G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (459 aa)
PRLHProlactin releasing hormone. (87 aa)
ADRA2BAlpha-2B adrenergic receptor; Alpha-2 adrenergic receptors mediate the catecholamine- induced inhibition of adenylate cyclase through the action of G proteins. (411 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
NPBWR1Neuropeptides B and W receptor 1; Belongs to the G-protein coupled receptor 1 family. (305 aa)
GCGGlucagon; Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis (By similarity). (180 aa)
TAC4Tachykinin-4; Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. (100 aa)
NPY2RG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (419 aa)
PTGIRProstaglandin I2 receptor; Belongs to the G-protein coupled receptor 1 family. (375 aa)
TAAR5Trace amine associated receptor 5; Belongs to the G-protein coupled receptor 1 family. (337 aa)
CHRNA5Cholinergic receptor nicotinic alpha 5 subunit. (474 aa)
CORTSomatostatin domain-containing protein. (106 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (460 aa)
MC5RMelanocortin 5 receptor. (412 aa)
BRS3Bombesin receptor subtype 3; Belongs to the G-protein coupled receptor 1 family. (398 aa)
P2RX5P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (432 aa)
GHRLUncharacterized protein. (234 aa)
GABRDUncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (694 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (640 aa)
MGRAMas-related G protein-coupled receptor A; Belongs to the G-protein coupled receptor 1 family. (325 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (419 aa)
AVPR2Vasopressin V2 receptor; Involved in renal water reabsorption. Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (449 aa)
THRAThyroid hormone receptor alpha. (452 aa)
KNG1Kininogen 1. (633 aa)
GHRGrowth hormone-binding protein; Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway (By similarity). (692 aa)
GRIK1Glutamate ionotropic receptor kainate type subunit 1. (949 aa)
CRHR1Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (429 aa)
CHRNA4Cholinergic receptor nicotinic alpha 4 subunit. (620 aa)
NPY5RNeuropeptide Y receptor Y5. (455 aa)
CHRNA6Cholinergic receptor nicotinic alpha 6 subunit. (542 aa)
OPRK1Opioid receptor kappa 1; Belongs to the G-protein coupled receptor 1 family. (515 aa)
HRH2Histamine receptor H2; Belongs to the G-protein coupled receptor 1 family. (492 aa)
GRIN2AGlutamate ionotropic receptor NMDA type subunit 2A. (1087 aa)
POMCNPP domain-containing protein. (285 aa)
S1PR2G_PROTEIN_RECEP_F1_2 domain-containing protein. (353 aa)
VIPR1Vasoactive intestinal peptide receptor 1; Belongs to the G-protein coupled receptor 2 family. (457 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (431 aa)
KISS1Uncharacterized protein. (244 aa)
GLP2RGlucagon like peptide 2 receptor; Belongs to the G-protein coupled receptor 2 family. (535 aa)
GRIA1Glutamate ionotropic receptor AMPA type subunit 1. (915 aa)
GABRB2Gamma-aminobutyric acid type A receptor beta2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (512 aa)
GRM8Glutamate metabotropic receptor 8. (908 aa)
HTR1E5-hydroxytryptamine receptor 1E. (365 aa)
GRIA4Glutamate ionotropic receptor AMPA type subunit 4. (902 aa)
PRSS2Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (257 aa)
CALCBCalcitonin related polypeptide beta. (174 aa)
PRLHRProlactin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (370 aa)
TSPOUncharacterized protein. (516 aa)
S1PR5Sphingosine-1-phosphate receptor 5; Belongs to the G-protein coupled receptor 1 family. (399 aa)
AVPUncharacterized protein. (285 aa)
FPR2Formyl peptide receptor 2; Belongs to the G-protein coupled receptor 1 family. (476 aa)
OXTOxytocin; Belongs to the vasopressin/oxytocin family. (173 aa)
EDN3Endothelin-3; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family. (210 aa)
NR3C1Glucocorticoid receptor; Receptor for glucocorticoids (GC). Has a dual mode of action: as a transcription factor that binds to glucocorticoid response elements (GRE), both for nuclear and mitochondrial DNA, and as a modulator of other transcription factors. Affects inflammatory responses, cellular proliferation and differentiation in target tissues. Involved in chromatin remodeling. Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP [...] (773 aa)
HTR75-hydroxytryptamine receptor 7; Belongs to the G-protein coupled receptor 1 family. (504 aa)
PTGER3Prostaglandin E2 receptor EP3 subtype; Receptor for prostaglandin E2 (PGE2). Required for normal development of fever in response to pyrinogens, including IL1B, prostaglandin E2 and bacterial lipopolysaccharide (LPS). Required for normal potentiation of platelet aggregation by prostaglandin E2, and thus plays a role in the regulation of blood coagulation. Required for increased HCO3(-) secretion in the duodenum in response to mucosal acidification, and thereby contributes to the protection of the mucosa against acid-induced ulceration. Not required for normal kidney function, normal ur [...] (438 aa)
CRHCRF domain-containing protein. (194 aa)
PARD3Par-3 family cell polarity regulator. (1340 aa)
ENSOCUP00000047896Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
HTR45-hydroxytryptamine receptor 4; Belongs to the G-protein coupled receptor 1 family. (418 aa)
GABBR1Gamma-aminobutyric acid type B receptor subunit 1. (1043 aa)
GRIA3Glutamate ionotropic receptor AMPA type subunit 3. (894 aa)
P2RY13Purinergic receptor P2Y13; Belongs to the G-protein coupled receptor 1 family. (355 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
VIPVasoactive intestinal peptide; VIP causes vasodilation, lowers arterial blood pressure, stimulates myocardial contractility, increases glycogenolysis and relaxes the smooth muscle of trachea, stomach and gall bladder; Belongs to the glucagon family. (166 aa)
PTGER4Prostaglandin E2 receptor EP4 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. (488 aa)
GABRR1Gamma-aminobutyric acid type A receptor rho1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (479 aa)
GABRR2Gamma-aminobutyric acid type A receptor rho2 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (464 aa)
TACR1Tachykinin receptor 1; Belongs to the G-protein coupled receptor 1 family. (407 aa)
OPRD1Opioid receptor delta 1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
EDN2Endothelin-2; Endothelins are endothelium-derived vasoconstrictor peptides; Belongs to the endothelin/sarafotoxin family. (360 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
PRLProlactin; Prolactin acts primarily on the mammary gland by promoting lactation. (262 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (764 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (774 aa)
NMBRNeuromedin B receptor; Belongs to the G-protein coupled receptor 1 family. (402 aa)
P2RX4P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (387 aa)
LPAR6Lysophosphatidic acid receptor 6; Belongs to the G-protein coupled receptor 1 family. (353 aa)
GRM4Glutamate metabotropic receptor 4. (1050 aa)
PTGFRProstaglandin F receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
CHRNA7Uncharacterized protein. (513 aa)
GLRA1Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
GRIK4Glutamate ionotropic receptor kainate type subunit 4. (956 aa)
PMCHPro-melanin concentrating hormone. (165 aa)
PTGDRProstaglandin D2 receptor. (293 aa)
VIPR2Vasoactive intestinal peptide receptor 2; Belongs to the G-protein coupled receptor 2 family. (439 aa)
GABRB3Gamma-aminobutyric acid type A receptor beta3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (471 aa)
TRHRThyrotropin releasing hormone receptor; Belongs to the G-protein coupled receptor 1 family. (398 aa)
GRIK2Glutamate ionotropic receptor kainate type subunit 2. (908 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues; Belongs to the somatotropin/prolactin family. (216 aa)
GIPGastric inhibitory polypeptide. (153 aa)
GLRBGlycine receptor beta; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (497 aa)
INSL5Insulin-like 5. (136 aa)
DRD1D(1A) dopamine receptor; Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase. (448 aa)
RXFP3G_PROTEIN_RECEP_F1_2 domain-containing protein. (465 aa)
CHRNA3Cholinergic receptor nicotinic alpha 3 subunit. (500 aa)
CHRNB3Cholinergic receptor nicotinic beta 3 subunit. (475 aa)
PDYNProdynorphin. (250 aa)
PTHParathyroid hormone. (131 aa)
GRIK3Glutamate ionotropic receptor kainate type subunit 3. (880 aa)
C5Complement C5. (1678 aa)
HCRTR1Hypocretin receptor 1. (416 aa)
GHRHGrowth hormone releasing hormone. (106 aa)
P2RY14Purinergic receptor P2Y14. (338 aa)
TRHThyrotropin releasing hormone. (280 aa)
GPR156G protein-coupled receptor 156. (801 aa)
LOC100354791G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (342 aa)
NPFFR2Neuropeptide FF receptor 2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
GRM1Glutamate metabotropic receptor 1. (1203 aa)
UTS2BUrotensin 2B. (119 aa)
LOC100344381Uncharacterized protein. (450 aa)
GHSRGrowth hormone secretagogue receptor type 1; Receptor for ghrelin, coupled to G-alpha-11 proteins. Stimulates growth hormone secretion. Binds also other growth hormone releasing peptides (GHRP) (e.g. Met-enkephalin and GHRP-6) as well as non-peptide, low molecular weight secretagogues (e.g. L-692,429, MK- 0677, adenosine) (By similarity). (366 aa)
AVPR1BVasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (417 aa)
GRM3Glutamate metabotropic receptor 3. (879 aa)
CHRNB1Cholinergic receptor nicotinic beta 1 subunit. (504 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (480 aa)
SSTSomatostatin. (116 aa)
TAAR2Trace amine associated receptor 2 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (349 aa)
CHRNA2Cholinergic receptor nicotinic alpha 2 subunit. (507 aa)
SCTRSecretin receptor; Receptor for secretin (SCT), which is involved in different processes such as regulation of the pH of the duodenal content, food intake and water homeostasis. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Upon binding to secretin, regulates the pH of the duodenum by (1) inhibiting the secretion of gastric acid from the parietal cells of the stomach and (2) stimulating the production of bicarbonate (NaHCO(3)) from the ductal cells of the pancreas (By similarity). In addition to regulating the pH of the duodena [...] (445 aa)
HCRTR2Hypocretin receptor 2; Belongs to the G-protein coupled receptor 1 family. (444 aa)
CCKBRGastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (454 aa)
GABRQGamma-aminobutyric acid type A receptor theta subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (610 aa)
GABRPGamma-aminobutyric acid type A receptor pi subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (440 aa)
MTNR1BMelatonin receptor 1B; Belongs to the G-protein coupled receptor 1 family. (362 aa)
TAAR9Trace amine associated receptor 9 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (348 aa)
CGAGlycoprotein hormones alpha chain; Shared alpha chain of the active heterodimeric glycoprotein hormones thyrotropin/thyroid stimulating hormone/TSH, lutropin/luteinizing hormone/LH and follitropin/follicle stimulating hormone/FSH. These hormones bind specific receptors on target cells that in turn activate downstream signaling pathways. (120 aa)
GABRA3Gamma-aminobutyric acid type A receptor alpha3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (496 aa)
FPR1fMet-Leu-Phe receptor; High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors. Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Receptor for TAFA4, mediates its effects on chemoattracting macrophages, promoting phagocytosis and increasing ROS release (By similarity). (352 aa)
ADORA2AAdenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (409 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
GRPGastrin releasing peptide. (130 aa)
SSTR2Somatostatin receptor 2; Belongs to the G-protein coupled receptor 1 family. (366 aa)
ADCYAP1Adenylate cyclase activating polypeptide 1. (176 aa)
TACR3Neuromedin-K receptor; This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity); Belongs to the G-protein coupled receptor 1 family. (467 aa)
GABREGamma-aminobutyric acid type A receptor epsilon subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (507 aa)
HTR1AG_PROTEIN_RECEP_F1_2 domain-containing protein. (422 aa)
ADMAdrenomedullin. (187 aa)
NPY1RNeuropeptide Y receptor Y1; Belongs to the G-protein coupled receptor 1 family. (383 aa)
HTR2A5-hydroxytryptamine receptor 2A. (469 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CHRNECholinergic receptor nicotinic epsilon subunit. (491 aa)
NTSNeurotensin. (170 aa)
NPYNeuropeptide Y; NPY is implicated in the control of feeding and in secretion of gonadotrophin-release hormone. (97 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase; Belongs to the G-protein coupled receptor 1 family. (328 aa)
HTR1D5-hydroxytryptamine receptor 1D; G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Regulates the release of 5-hydroxytryptamine in the brain, and thereby affects neural activity. May also play a role in regulating the release of other neurotransmitte [...] (377 aa)
FSHRFollicle-stimulating hormone receptor; G protein-coupled receptor for follitropin, the follicle- stimulating hormone. Through cAMP production activates the downstream PI3K-AKT and ERK1/ERK2 signaling pathways. (703 aa)
GRID2Glutamate ionotropic receptor delta type subunit 2. (1007 aa)
GLRA2Glycine receptor alpha 2; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (452 aa)
GABRG3Gamma-aminobutyric acid type A receptor gamma3 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (460 aa)
TRPV1Transient receptor potential cation channel subfamily V member 1; Ligand-activated non-selective calcium permeant cation channel involved in detection of noxious chemical and thermal stimuli. Seems to mediate proton influx and may be involved in intracellular acidosis in nociceptive neurons. Involved in mediation of inflammatory pain and hyperalgesia. Sensitized by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases, which involves PKC isozymes and PCL. Can be activated by endogenous compounds, including 12-hydroperoxytetraenoic acid and bradykinin. Ac [...] (842 aa)
AGTR2Angiotensin receptor 2; Belongs to the G-protein coupled receptor 1 family. (363 aa)
PTGER2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
GRM5Glutamate metabotropic receptor 5. (988 aa)
GRID1Glutamate ionotropic receptor delta type subunit 1. (1051 aa)
GRPRGastrin releasing peptide receptor; Belongs to the G-protein coupled receptor 1 family. (425 aa)
GABRA5Gamma-aminobutyric acid type A receptor alpha5 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (463 aa)
PYYPeptide YY(3-36); This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility. (233 aa)
HCRTOrexin; Neuropeptides that play a significant role in the regulation of food intake and sleep-wakefulness, possibly by coordinating the complex behavioral and physiologic responses of these complementary homeostatic functions. A broader role in the homeostatic regulation of energy metabolism, autonomic function, hormonal balance and the regulation of body fluids, is also suggested. Belongs to the orexin family. (130 aa)
EDN1Big endothelin-1; Endothelins are endothelium-derived vasoconstrictor peptides (By similarity). Probable ligand for G-protein coupled receptors EDNRA and EDNRB which activates PTK2B, BCAR1, BCAR3 and, GTPases RAP1 and RHOA cascade in glomerular mesangial cells (By similarity). Belongs to the endothelin/sarafotoxin family. (202 aa)
RLN3Relaxin 3. (172 aa)
CCKARCholecystokinin receptor type A; Receptor for cholecystokinin. Mediates pancreatic growth and enzyme secretion, smooth muscle contraction of the gall bladder and stomach. Has a 1000-fold higher affinity for CCK rather than for gastrin. It modulates feeding and dopamine-induced behavior in the central and peripheral nervous system. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). (426 aa)
NMUR2Neuromedin U receptor 2; Belongs to the G-protein coupled receptor 1 family. (420 aa)
UCN3Urocortin 3. (167 aa)
CALCRLCalcitonin receptor like receptor; Belongs to the G-protein coupled receptor 2 family. (465 aa)
GNRH1Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
NPY4RNeuropeptide Y receptor Y4; Belongs to the G-protein coupled receptor 1 family. (375 aa)
P2RY10P2Y receptor family member 10. (340 aa)
P2RX6P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (418 aa)
MLNRMotilin receptor; Belongs to the G-protein coupled receptor 1 family. (400 aa)
BDKRB2B2 bradykinin receptor; Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. (446 aa)
GABRA6Gamma-aminobutyric acid type A receptor alpha6 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (453 aa)
GRIN2BGlutamate ionotropic receptor NMDA type subunit 2B. (1484 aa)
LOC100346285Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (367 aa)
GPR83G protein-coupled receptor 83; Belongs to the G-protein coupled receptor 1 family. (422 aa)
GABRA1Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (470 aa)
CHRM4Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (478 aa)
RXFP2Relaxin family peptide receptor 2. (745 aa)
LPAR1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (391 aa)
BDKRB1B1 bradykinin receptor; This is a receptor for bradykinin. Could be a factor in chronic pain and inflammation. (497 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (517 aa)
P2RY8P2Y receptor family member 8; Belongs to the G-protein coupled receptor 1 family. (382 aa)
MC4RMelanocortin 4 receptor. (333 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (401 aa)
PTH2Parathyroid hormone 2. (97 aa)
MC2RMelanocortin 2 receptor. (372 aa)
ADRB3G_PROTEIN_RECEP_F1_2 domain-containing protein. (407 aa)
RXFP4G_PROTEIN_RECEP_F1_2 domain-containing protein. (373 aa)
G1TX71_RABITPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (213 aa)
GRIN2CUncharacterized protein; Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. (671 aa)
LOC100355052G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (342 aa)
CHRM5Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (532 aa)
CHRNA9Cholinergic receptor nicotinic alpha 9 subunit. (479 aa)
CALCRCalcitonin receptor; This is a receptor for calcitonin. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. The calcitonin receptor is thought to couple to the heterotrimeric guanosine triphosphate-binding protein that is sensitive to cholera toxin. Isoform 2 has altered ligand binding and abolished coupling to phospholipase C. (491 aa)
C5AR1C5a anaphylatoxin chemotactic receptor 1; Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. The ligand interacts with at least two sites on the receptor: a high-affinity site on the extracellular N- terminus, and a second site in the transmembrane region which activates downstream signaling events. Receptor activation stimulates chemotaxis, granule enzyme release, intracellular calcium release and superoxide anion production (By similarity). (348 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (599 aa)
GABRA4Gamma-aminobutyric acid type A receptor alpha4 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (517 aa)
MTNR1AMelatonin receptor 1A; Belongs to the G-protein coupled receptor 1 family. (312 aa)
ADORA2BAdenosine receptor A2b; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase (By similarity). Belongs to the G-protein coupled receptor 1 family. (444 aa)
LOC100345534Gastrin domain-containing protein. (115 aa)
GRIN3AGlutamate ionotropic receptor NMDA type subunit 3A. (1115 aa)
NPY6RNeuropeptide Y receptor type 6; Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. (371 aa)
P2RX1P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (399 aa)
NMUR1Neuromedin U receptor 1; Belongs to the G-protein coupled receptor 1 family. (394 aa)
LTB4RLeukotriene B4 receptor; Belongs to the G-protein coupled receptor 1 family. (363 aa)
RELH_RABITRelaxin-like protein SQ10 A chain. (178 aa)
P2RY1Purinergic receptor P2Y1; Belongs to the G-protein coupled receptor 1 family. (373 aa)
GABRB1Neur_chan_memb domain-containing protein. (182 aa)
DRD5Dopamine receptor D5; Belongs to the G-protein coupled receptor 1 family. (483 aa)
NPFFNeuropeptide FF-amide peptide precursor. (114 aa)
PPYPancreatic hormone; Pancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions; Belongs to the NPY family. (95 aa)
TACR2Substance-K receptor; This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (384 aa)
LHBLutropin subunit beta; Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids. (141 aa)
CHRNDCholinergic receptor nicotinic delta subunit. (695 aa)
DRD3Dopamine receptor D3; Belongs to the G-protein coupled receptor 1 family. (399 aa)
P2RY11G_PROTEIN_RECEP_F1_2 domain-containing protein. (297 aa)
TAAR4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (390 aa)
HTR5A5-hydroxytryptamine receptor 5A. (358 aa)
ADRA1BG_PROTEIN_RECEP_F1_2 domain-containing protein. (494 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (732 aa)
ADRA1AAlpha-1A adrenergic receptor; This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine (PE)-stimulated ERK signaling in cardiac myocytes (By similarity); Belongs to the G-protein coupled receptor 1 family. Adrenergic receptor subfamily. ADRA1A sub-subfamily. (466 aa)
P2RX3P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (410 aa)
AGTR1Type-1 angiotensin II receptor; Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. (425 aa)
TAC3Uncharacterized protein. (281 aa)
LOC108178086Uncharacterized protein. (144 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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