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| | RAC1 | Rac family small GTPase 1. (199 aa) |
| | CFL2 | Cofilin 2; Belongs to the actin-binding proteins ADF family. (195 aa) |
| | TRPC5 | Short transient receptor potential channel 5; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Has also been shown to be calcium-selective. May also be activated by intracellular calcium store depletion. (974 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) |
| | RGS3 | Regulator of G protein signaling 3. (1006 aa) |
| | PAK2 | Serine/threonine-protein kinase PAK 2; Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell motility, cell cycle progression, apoptosis or proliferation. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Full-length PAK2 stimulates cell survival and cell growth. Phosphorylates MAPK4 and MAPK6 and activates the downstream targ [...] (524 aa) |
| | SEMA3G | Semaphorin 3G; Belongs to the semaphorin family. (777 aa) |
| | SEMA6D | Semaphorin 6D; Belongs to the semaphorin family. (1086 aa) |
| | NCK1 | Cytoplasmic protein. (377 aa) |
| | EPHB6 | EPH receptor B6. (1015 aa) |
| | UNC5B | Unc-5 netrin receptor B. (946 aa) |
| | EPHA4 | EPH receptor A4. (986 aa) |
| | SEMA5B | Semaphorin 5B. (1077 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | SEMA4F | Ssemaphorin 4F; Belongs to the semaphorin family. (721 aa) |
| | RASA1 | RAS p21 protein activator 1. (967 aa) |
| | NRP1 | Neuropilin; Belongs to the neuropilin family. (950 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | EFNA1 | Ephrin A1; Belongs to the ephrin family. (205 aa) |
| | EPHB1 | Receptor protein-tyrosine kinase. (984 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (830 aa) |
| | MET | Hepatocyte growth factor receptor; Receptor tyrosine kinase that transduces signals from the extracellular matrix into the cytoplasm by binding to hepatocyte growth factor/HGF ligand. Regulates many physiological processes including proliferation, scattering, morphogenesis and survival. Ligand binding at the cell surface induces autophosphorylation of MET on its intracellular domain that provides docking sites for downstream signaling molecules. Following activation by ligand, interacts with the PI3-kinase subunit PIK3R1, PLCG1, SRC, GRB2, STAT3 or the adapter GAB1. Recruitment of thes [...] (1540 aa) |
| | PLXNA2 | Plexin A2. (1897 aa) |
| | SEMA4C | Semaphorin 4C; Belongs to the semaphorin family. (832 aa) |
| | PTCH1 | Patched 1. (1321 aa) |
| | SEMA4G | Semaphorin 4G; Belongs to the semaphorin family. (843 aa) |
| | SEMA6C | Sema domain-containing protein; Belongs to the semaphorin family. (948 aa) |
| | ROBO3 | Roundabout guidance receptor 3. (1397 aa) |
| | ROBO1 | Roundabout guidance receptor 1. (1651 aa) |
| | SEMA3B | Semaphorin 3B; Belongs to the semaphorin family. (757 aa) |
| | PLXNB1 | Plexin B1. (2118 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | GNAI1 | G protein subunit alpha i1. (349 aa) |
| | EPHA7 | EPH receptor A7. (998 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | PDK1 | Protein-serine/threonine kinase. (396 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (325 aa) |
| | PAK3 | Non-specific serine/threonine protein kinase. (652 aa) |
| | PARD3 | Par-3 family cell polarity regulator. (1340 aa) |
| | DPYSL5 | Dihydropyrimidinase like 5. (662 aa) |
| | SLIT3 | Slit guidance ligand 3. (1530 aa) |
| | ILK | Integrin linked kinase. (510 aa) |
| | SSH2 | Slingshot protein phosphatase 2. (1446 aa) |
| | PPP3CA | Serine/threonine-protein phosphatase. (695 aa) |
| | NFATC2 | Nuclear factor of activated T cells 2. (900 aa) |
| | NTN4 | Netrin 4. (697 aa) |
| | BMPR1B | Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (543 aa) |
| | EFNB2 | Ephrin B2; Belongs to the ephrin family. (332 aa) |
| | SEMA3C | Semaphorin 3C; Belongs to the semaphorin family. (751 aa) |
| | DCC | DCC netrin 1 receptor. (1425 aa) |
| | EFNA3 | Ephrin RBD domain-containing protein; Belongs to the ephrin family. (330 aa) |
| | ARHGEF12 | Rho guanine nucleotide exchange factor 12. (1544 aa) |
| | PLXNA3 | Sema domain-containing protein. (1995 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (469 aa) |
| | NTNG2 | Netrin G2. (618 aa) |
| | ABL1 | Tyrosine-protein kinase. (1118 aa) |
| | PTK2-2 | FERM_N_2 domain-containing protein. (121 aa) |
| | EFNA4 | Ephrin A4; Belongs to the ephrin family. (204 aa) |
| | SEMA4A | Semaphorin 4A; Belongs to the semaphorin family. (977 aa) |
| | EFNB1 | Ephrin B1; Belongs to the ephrin family. (370 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1060 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (585 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (701 aa) |
| | SEMA6A | Semaphorin 6A; Belongs to the semaphorin family. (1038 aa) |
| | EPHB4 | EPH receptor B4. (1011 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity (By similarity). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A (By similarity). Phosphorylates FHOD1 and acts synergistically with it to promote SRC- dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 [...] (1352 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (857 aa) |
| | ABLIM3 | Actin binding LIM protein family member 3. (684 aa) |
| | PAK4 | P21 (RAC1) activated kinase 4. (726 aa) |
| | SEMA7A | Sema domain-containing protein; Belongs to the semaphorin family. (408 aa) |
| | EPHA1 | EPH receptor A1. (948 aa) |
| | NFATC4 | Nuclear factor of activated T cells 4. (933 aa) |
| | UNC5D | Unc-5 netrin receptor D. (958 aa) |
| | PLXNA4 | Plexin A4. (1912 aa) |
| | PPP3CC | Serine/threonine-protein phosphatase. (574 aa) |
| | LIMK2 | LIM domain kinase 2. (693 aa) |
| | SMO | Smoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (787 aa) |
| | EPHA6 | EPH receptor A6. (1130 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | DPYSL2 | Dihydropyrimidinase like 2. (572 aa) |
| | UNC5C | Unc-5 netrin receptor C. (931 aa) |
| | RND1 | Rho family GTPase 1. (232 aa) |
| | NTNG1 | Netrin G1. (539 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (603 aa) |
| | TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (929 aa) |
| | NCK2 | Cytoplasmic protein. (380 aa) |
| | TRPC3 | Transient receptor potential cation channel subfamily C member 3. (991 aa) |
| | PAK6 | Non-specific serine/threonine protein kinase. (681 aa) |
| | G1U2H9_RABIT | F-BAR domain-containing protein. (334 aa) |
| | CDK5 | Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa) |
| | ABLIM1 | Actin binding LIM protein 1. (831 aa) |
| | LIMK1 | LIM domain kinase 1. (645 aa) |
| | RYK | Receptor like tyrosine kinase. (553 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | LOC100348967 | Uncharacterized protein. (316 aa) |
| | PPP3CB | Serine/threonine-protein phosphatase. (518 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | L1CAM | Uncharacterized protein. (1256 aa) |
| | GDF7 | Growth differentiation factor 7. (546 aa) |
| | NTN1 | Netrin 1. (533 aa) |
| | EPHA2 | EPH receptor A2. (1031 aa) |
| | LOC100346856 | Uncharacterized protein. (316 aa) |
| | LOC100356250 | Uncharacterized protein. (292 aa) |
| | CAMK2A | Calcium/calmodulin dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (469 aa) |
| | TRPC1 | Short transient receptor potential channel 1; Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Seems to be also activated by intracellular calcium store depletion; Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC1 sub-subfamily. (793 aa) |
| | EPHA5 | Uncharacterized protein. (958 aa) |
| | LRRC4C | Leucine rich repeat containing 4C. (640 aa) |
| | PLXNC1 | Plexin_cytopl domain-containing protein. (428 aa) |
| | SHH | Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (451 aa) |
| | EFNA5 | Ephrin A5; Belongs to the ephrin family. (228 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (371 aa) |
| | FYN | Tyrosine-protein kinase. (537 aa) |
| | EPHA8 | EPH receptor A8. (973 aa) |
| | SEMA4B | Semaphorin 4B; Belongs to the semaphorin family. (832 aa) |
| | MYL12A | Myosin light chain 12A. (172 aa) |
| | LOC100345250 | Uncharacterized protein. (461 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (381 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (364 aa) |
| | EPHB2 | EPH receptor B2. (966 aa) |
| | SSH1 | Slingshot protein phosphatase 1. (1196 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | SEMA4D | Semaphorin 4D; Belongs to the semaphorin family. (864 aa) |
| | EPHB3 | EPH receptor B3. (1075 aa) |
| | TRPC4 | Transient receptor potential cation channel subfamily C member 4; Belongs to the transient receptor (TC 1.A.4) family. (982 aa) |
| | SRGAP2 | Uncharacterized protein. (998 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | SEMA3D | Semaphorin 3D; Belongs to the semaphorin family. (777 aa) |
| | SEMA3A | Semaphorin 3A; Belongs to the semaphorin family. (770 aa) |
| | SEMA3F | Semaphorin 3F; Belongs to the semaphorin family. (784 aa) |
| | BOC | BOC cell adhesion associated, oncogene regulated. (1111 aa) |
| | PAK5 | Non-specific serine/threonine protein kinase. (719 aa) |
| | EPHA3 | EPH receptor A3. (984 aa) |
| | NFATC3 | Nuclear factor of activated T cells 3. (1070 aa) |
| | SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1. (1085 aa) |
