STRINGSTRING
POLR2L POLR2L POLR3A POLR3A MAVS MAVS STING1 STING1 CHUK CHUK POLR3B POLR3B POLR3E POLR3E TBK1 TBK1 IKBKG IKBKG ADAR ADAR CASP1 CASP1 IRF7 IRF7 LOC100353390 LOC100353390 CCL5 CCL5 POLR3C POLR3C LOC100353390-2 LOC100353390-2 PYCARD PYCARD IL18 IL18 POLR1C POLR1C POLR3GL POLR3GL POLR2H POLR2H IKBKB IKBKB POLR3H POLR3H RIPK1 RIPK1 POLR2F POLR2F POLR3K POLR3K IL33 IL33 POLR3F POLR3F NFKBIA NFKBIA CXCL10 CXCL10 POLR2K-2 POLR2K-2 POLR3D POLR3D LOC100355669 LOC100355669 IL6 IL6 LOC100354654 LOC100354654 NFKBIB NFKBIB LOC100357194 LOC100357194 POLR3G POLR3G DDX58 DDX58 TREX1 TREX1 IFNB1 IFNB1 IL1B IL1B NFKB1 NFKB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
POLR2LUncharacterized protein. (62 aa)
POLR3ADNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1402 aa)
MAVSMitochondrial antiviral signaling protein. (541 aa)
STING1Transmembrane protein 173. (426 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (1057 aa)
POLR3BDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1620 aa)
POLR3ERNA polymerase III subunit E. (721 aa)
TBK1TANK binding kinase 1. (836 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (686 aa)
ADARAdenosine deaminase RNA specific. (1182 aa)
CASP1Uncharacterized protein; Belongs to the peptidase C14A family. (418 aa)
IRF7Interferon regulatory factor 7. (438 aa)
LOC100353390Uncharacterized protein. (189 aa)
CCL5C-C motif chemokine. (91 aa)
POLR3CRNA polymerase III subunit C3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (554 aa)
LOC100353390-2Uncharacterized protein. (190 aa)
PYCARDPYD and CARD domain containing. (196 aa)
IL18Uncharacterized protein. (408 aa)
POLR1CRNA polymerase I and III subunit C. (344 aa)
POLR3GLDNA-directed RNA polymerase III subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. (217 aa)
POLR2HDNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (150 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
POLR3HRNA polymerase III subunit H. (268 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (670 aa)
POLR2FRNA polymerase II subunit F. (127 aa)
POLR3KDNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (108 aa)
IL33Uncharacterized protein. (142 aa)
POLR3FDNA-directed RNA polymerase III subunit RPC6; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs; Belongs to the eukaryotic RPC34/RPC39 RNA polymerase subunit family. (316 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
CXCL10C-X-C motif chemokine. (98 aa)
POLR2K-2Uncharacterized protein. (58 aa)
POLR3DRNA polymerase III subunit D. (398 aa)
LOC100355669Uncharacterized protein. (190 aa)
IL6Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa)
LOC100354654Uncharacterized protein. (189 aa)
NFKBIBNFKB inhibitor beta. (356 aa)
LOC100357194Uncharacterized protein. (189 aa)
POLR3GUncharacterized protein. (223 aa)
DDX58DExD/H-box helicase 58. (954 aa)
TREX1Three prime repair exonuclease 1. (314 aa)
IFNB1Interferon beta 1. (180 aa)
IL1BInterleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa)
NFKB1Nuclear factor kappa B subunit 1. (968 aa)
Your Current Organism:
Oryctolagus cuniculus
NCBI taxonomy Id: 9986
Other names: European rabbit, Japanese white rabbit, Lepus cuniculus, New Zealand rabbit, O. cuniculus, domestic rabbit, rabbit, rabbits
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