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| | RAC1 | Rac family small GTPase 1. (199 aa) |
| | MSN | FERM domain-containing protein. (577 aa) |
| | CLDN23 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (298 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
| | GNAI1 | G protein subunit alpha i1. (349 aa) |
| | CXCR4 | C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (366 aa) |
| | ITK | Tyrosine-protein kinase. (611 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (830 aa) |
| | PTPN11 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | OCLN | Occludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (521 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | CLDN11 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | CLDN7 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | TXK | Tyrosine-protein kinase. (556 aa) |
| | CTNNA1 | Catenin alpha-1; Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and [...] (993 aa) |
| | THY1 | Thy-1 cell surface antigen. (161 aa) |
| | CLDN8 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (235 aa) |
| | CLDN10 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa) |
| | CDH5 | Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (974 aa) |
| | CLDN15 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa) |
| | CLDN4 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa) |
| | CLDN1 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa) |
| | CLDN16 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (292 aa) |
| | CLDN20 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | LOC100345250 | Uncharacterized protein. (461 aa) |
| | ITGAL | Integrin subunit alpha L; Belongs to the integrin alpha chain family. (1241 aa) |
| | MYL12A | Myosin light chain 12A. (172 aa) |
| | RAPGEF4 | Rap guanine nucleotide exchange factor 4. (1011 aa) |
| | PECAM1 | Platelet and endothelial cell adhesion molecule 1. (768 aa) |
| | CD99L2 | CD99 molecule like 2. (267 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1415 aa) |
| | CLDN6 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa) |
| | MYLPF | Myosin regulatory light chain 2, skeletal muscle isoform type 2. (200 aa) |
| | LOC100356250 | Uncharacterized protein. (292 aa) |
| | LOC100346856 | Uncharacterized protein. (316 aa) |
| | CLDN17 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (223 aa) |
| | CLDN14 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (236 aa) |
| | PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (996 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | NCF4 | P40-phox. (340 aa) |
| | CLDN2 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (306 aa) |
| | ARHGAP5 | Rho GTPase activating protein 5. (1503 aa) |
| | CLDN25 | Claudin 25. (229 aa) |
| | LOC100348967 | Uncharacterized protein. (316 aa) |
| | MYL10 | Myosin light chain 10. (167 aa) |
| | ACTN4 | Actinin alpha 4. (653 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1266 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa) |
| | LOC108175401 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | CLDN22 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa) |
| | RAPGEF3 | Ras-GEF domain-containing protein. (195 aa) |
| | CLDN19 | Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (313 aa) |
| | MMP9 | Matrix metalloproteinase-9; Could play a role in bone osteoclastic resorption. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments (By similarity). (707 aa) |
| | JAM2 | Junctional adhesion molecule 2. (297 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | ICAM1 | Intercellular adhesion molecule 1. (534 aa) |
| | ITGAM | Integrin subunit alpha M; Belongs to the integrin alpha chain family. (1258 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa) |
| | VASP | WH1 domain-containing protein. (147 aa) |
| | CTNNA2 | Catenin alpha 2. (953 aa) |
| | CTNNA3 | Catenin alpha 3. (895 aa) |
| | RASSF5 | Ras association domain family member 5. (324 aa) |
| | CLDN34 | Uncharacterized protein. (223 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (416 aa) |
| | ROCK1 | Rho-associated protein kinase 1; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity (By similarity). Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, TPPP, PFN1 and PPP1R12A (By similarity). Phosphorylates FHOD1 and acts synergistically with it to promote SRC- dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 [...] (1352 aa) |
| | VAV3 | Vav guanine nucleotide exchange factor 3. (964 aa) |
| | BCAR1 | BCAR1 scaffold protein, Cas family member. (869 aa) |
| | PTK2-2 | FERM_N_2 domain-containing protein. (121 aa) |
| | F11R | F11 receptor. (314 aa) |
| | VCL | Vinculin. (1241 aa) |
| | ACTN1 | Actinin alpha 1. (1038 aa) |
| | EZR | Ezrin; Probably involved in connections of major cytoskeletal structures to the plasma membrane (By similarity). In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis (By similarity). (653 aa) |
| | ITGB2 | Integrin beta. (1009 aa) |
| | CTNND1 | Catenin delta 1. (967 aa) |
| | RAP1A | Uncharacterized protein. (184 aa) |
| | RAP1B | Uncharacterized protein. (184 aa) |
| | JAM3 | Junctional adhesion molecule 3. (405 aa) |
| | ACTB | Uncharacterized protein. (357 aa) |
| | PRKCB | Protein kinase C beta type; Calcium-activated, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase involved in various cellular processes such as regulation of the B-cell receptor (BCR) signalosome, oxidative stress-induced apoptosis, androgen receptor-dependent transcription regulation, insulin signaling and endothelial cells proliferation. Plays a key role in B-cell activation by regulating BCR- induced NF-kappa-B activation. Mediates the activation of the canonical NF-kappa-B pathway (NFKB1) by direct phosphorylation of CARD11/CARMA1 at 'Ser-559', 'Ser- [...] (638 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (399 aa) |
| | NCF2 | Uncharacterized protein. (542 aa) |
