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| | G1TUQ7_RABIT | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CASP8 | DED domain-containing protein. (109 aa) |
| | LEF1 | Lymphoid enhancer binding factor 1. (414 aa) |
| | PAK3 | Non-specific serine/threonine protein kinase. (652 aa) |
| | TLR9 | TIR domain-containing protein. (1027 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (399 aa) |
| | FLNC | Filamin C. (2628 aa) |
| | DYNC2H1 | Dynein cytoplasmic 2 heavy chain 1. (4313 aa) |
| | ACTB | Uncharacterized protein. (357 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (472 aa) |
| | KLC4 | Kinesin light chain 4. (674 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (686 aa) |
| | GAPDH | Glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubu [...] (333 aa) |
| | WASF3 | WASP family member 3. (502 aa) |
| | PFN4 | Uncharacterized protein; Belongs to the profilin family. (201 aa) |
| | ENSOCUP00000042214 | Dynein light chain. (73 aa) |
| | CYFIP2 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1278 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | JUN | BZIP domain-containing protein; Belongs to the bZIP family. (352 aa) |
| | DNM2 | Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (846 aa) |
| | EXOC5 | Uncharacterized protein. (192 aa) |
| | ELMO2 | Engulfment and cell motility 2. (732 aa) |
| | TXN | Thioredoxin; Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions (By similarity). Plays a role in the reversible S-nitrosylation of cysteine residues in target proteins, and thereby contributes to the response to intracellular nitric oxide. Nitrosylates the active site Cys of CASP3 in response to nitric oxide (NO), and thereby inhibits caspase-3 activity. Induces the FOS/JUN AP-1 DNA binding activity in ionizing radiation (IR) cells through its oxidation/reduction status [...] (105 aa) |
| | RHOB | Ras homolog family member B. (196 aa) |
| | KPNA3 | Importin subunit alpha; Functions in nuclear protein import. (530 aa) |
| | PAK1 | Non-specific serine/threonine protein kinase. (585 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (346 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (701 aa) |
| | TXN2 | Thioredoxin 2. (166 aa) |
| | BCL2 | BH4_2 domain-containing protein. (389 aa) |
| | ARHGEF26 | Rho guanine nucleotide exchange factor 26. (937 aa) |
| | MAP2K4 | Mitogen-activated protein kinase kinase 4. (520 aa) |
| | KLC1 | Uncharacterized protein. (808 aa) |
| | DYNC1I2 | Dynein cytoplasmic 1 intermediate chain 2. (638 aa) |
| | MYD88 | Uncharacterized protein. (476 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (416 aa) |
| | FLNB | Filamin-B; Connects cell membrane constituents to the actin cytoskeleton. May promote orthogonal branching of actin filaments and links actin filaments to membrane glycoproteins. Anchors various transmembrane proteins to the actin cytoskeleton (By similarity). (2695 aa) |
| | TIRAP | TIR domain containing adaptor protein. (234 aa) |
| | NCKAP1 | NCK associated protein 1. (1134 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (464 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (1057 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (439 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (534 aa) |
| | RAB7B | Uncharacterized protein. (280 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (899 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (396 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1673 aa) |
| | ARPC1A | Actin related protein 2/3 complex subunit 1A. (508 aa) |
| | BRK1 | BRICK1 subunit of SCAR/WAVE actin nucleating complex. (75 aa) |
| | MYL2 | Myosin regulatory light chain 2, ventricular/cardiac muscle isoform; Contractile protein that plays a role in heart development and function (By similarity). Following phosphorylation, plays a role in cross-bridge cycling kinetics and cardiac muscle contraction by increasing myosin lever arm stiffness and promoting myosin head diffusion; as a consequence of the increase in maximum contraction force and calcium sensitivity of contraction force. These events altogether slow down myosin kinetics and prolong duty cycle resulting in accumulated myosins being cooperatively recruited to actin [...] (232 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (210 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | AHNAK | Uncharacterized protein. (2159 aa) |
| | LOC100343501 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (196 aa) |
| | ARPC4 | Actin-related protein 2/3 complex subunit 4; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament; Belongs to the ARPC4 family. (187 aa) |
| | DYNLL1 | Dynein light chain 1, cytoplasmic; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures (By similarity). Promotes transactivation functions of ESR1 and plays a role in the nuclear localization of ESR1. (89 aa) |
| | SNX33 | Sorting nexin 33. (536 aa) |
| | VPS39 | VPS39 subunit of HOPS complex. (885 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1686 aa) |
| | ARF1-2 | Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | RHOH | Ras homolog family member H. (191 aa) |
| | MYO6 | Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1285 aa) |
| | STX10 | Syntaxin 10; Belongs to the syntaxin family. (358 aa) |
| | B7NZQ1_RABIT | FLNA protein (Predicted). (780 aa) |
| | RALA-2 | Uncharacterized protein. (206 aa) |
| | FBXO22 | F-box protein 22. (299 aa) |
| | LOC100357840 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | CYTH1 | Cytohesin 1. (416 aa) |
| | IL1B | Interleukin-1 beta; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells; Belongs to the IL-1 family. (234 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | LOC108178730 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | DYNLRB1 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | MYL10 | Myosin light chain 10. (167 aa) |
| | LOC100348967 | Uncharacterized protein. (316 aa) |
| | SKP1 | Uncharacterized protein; Belongs to the SKP1 family. (163 aa) |
| | LOC100353673 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC100356070 | Profilin; Belongs to the profilin family. (153 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CXCL8 | Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa) |
| | FHOD1 | Formin homology 2 domain containing 1. (1137 aa) |
| | TRADD | TNFRSF1A associated via death domain. (447 aa) |
| | RPS3 | Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family. (281 aa) |
| | MAP2K7 | Mitogen-activated protein kinase kinase 7. (435 aa) |
| | LOC100341515 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC100340957 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (734 aa) |
| | IL6 | Interleukin-6; Cytokine with a wide variety of biological functions. It is a potent inducer of the acute phase response. Plays an essential role in the final differentiation of B-cells into Ig-secreting cells Involved in lymphocyte and monocyte differentiation. Acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. Required for the generation of T(H)17 cells. Also acts as a myokine. It is discharged into the bloodstream after muscle contraction and acts to increase the breakdown of fats and to improve insulin resistance. It induces myeloma and plasm [...] (241 aa) |
| | VPS11 | Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (941 aa) |
| | LOC100346856 | Uncharacterized protein. (316 aa) |
| | CYTH4 | Cytohesin 4. (394 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | LOC100354468 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC100356250 | Uncharacterized protein. (292 aa) |
| | MYLPF | Myosin regulatory light chain 2, skeletal muscle isoform type 2. (200 aa) |
| | GCC2 | GRIP and coiled-coil domain containing 2. (1684 aa) |
| | M6PR | Mannose-6-phosphate receptor, cation dependent. (285 aa) |
| | RHOG | Ras homolog family member G. (191 aa) |
| | DYNLL2 | Dynein light chain. (168 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (917 aa) |
| | HSP90B1 | Endoplasmin; Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors. Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity. (802 aa) |
| | TCF7 | Transcription factor 7. (319 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | HSP90AB1 | Heat shock protein HSP 90-beta; Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co- chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Engages with a range of client protein classes via its interact [...] (726 aa) |
| | TNFSF10 | Tumor necrosis factor ligand superfamily member. (304 aa) |
| | PIK3C2G | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1501 aa) |
| | MYL12A | Myosin light chain 12A. (172 aa) |
| | ACBD3 | Acyl-CoA binding domain containing 3. (528 aa) |
| | MYC | Myc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (438 aa) |
| | RAB5B | RAB5B, member RAS oncogene family. (290 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (381 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (364 aa) |
| | NCKAP1L | NCK associated protein 1 like. (1181 aa) |
| | RHOA | Ras homolog family member A. (193 aa) |
| | RAB5C | Uncharacterized protein. (216 aa) |
| | DYNLT1 | Dynein light chain Tctex-type 1. (113 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | VPS16 | Vacuolar protein sorting-associated protein 16 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS16 family. (839 aa) |
| | DYNC1I1 | Dynein cytoplasmic 1 intermediate chain 1. (653 aa) |
| | RAB5A | Uncharacterized protein. (215 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1310 aa) |
| | ARPC3 | Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (178 aa) |
| | RIPK1 | Receptor interacting serine/threonine kinase 1. (670 aa) |
| | CASP7 | Caspase 7; Belongs to the peptidase C14A family. (303 aa) |
| | CYFIP1 | Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1272 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (591 aa) |
| | RAC1 | Rac family small GTPase 1. (199 aa) |
| | DYNLT3 | Uncharacterized protein. (161 aa) |
| | DYNLRB2 | Dynein light chain roadblock; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. (96 aa) |
| | PLEKHM1 | Pleckstrin homology and RUN domain containing M1. (1156 aa) |
| | WASL | WASP like actin nucleation promoting factor. (512 aa) |
| | TAB3 | TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (730 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | CASP4 | Uncharacterized protein; Belongs to the peptidase C14A family. (361 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | PFN2 | Profilin; Belongs to the profilin family. (91 aa) |
| | TLR6 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (795 aa) |
| | ARPC2 | Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (322 aa) |
| | CSE1L | Chromosome segregation 1 like. (1038 aa) |
| | NLRP3 | NLR family pyrin domain containing 3. (1046 aa) |
| | RHOJ | Ras homolog family member J. (214 aa) |
| | DYNC2LI1 | Dynein cytoplasmic 2 light intermediate chain 1. (352 aa) |
| | NOD1 | Nucleotide binding oligomerization domain containing 1. (953 aa) |
| | IL18 | Uncharacterized protein. (408 aa) |
| | S100a10 | Protein S100-A10; Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine-specific kinase. (198 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | VPS18 | VPS18 core subunit of CORVET and HOPS complexes. (973 aa) |
| | DYNC1LI2 | Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (628 aa) |
| | PLEKHM2 | Pleckstrin homology and RUN domain containing M2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (1157 aa) |
| | PYCARD | PYD and CARD domain containing. (196 aa) |
| | FYCO1 | FYVE and coiled-coil domain containing 1. (1470 aa) |
| | CD14 | Monocyte differentiation antigen CD14; Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell su [...] (372 aa) |
| | TLR2 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (784 aa) |
| | ELMO1 | Engulfment and cell motility 1. (742 aa) |
| | ARPC5L | Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (153 aa) |
| | KPNA1 | Importin subunit alpha; Functions in nuclear protein import. (538 aa) |
| | VPS33A | Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family. (595 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa) |
| | GSDMD | Gasdermin D. (471 aa) |
| | KPNA4 | Importin subunit alpha; Functions in nuclear protein import. (523 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | RAB7A | Ras-related protein Rab-7a; Key regulator in endo-lysosomal trafficking. Governs early- to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positioning, and endosome-lysosome transport through different protein-protein interaction cascades (By similarity). Plays a central role, not only in endosomal traffic, but also in many other cellular and physiological events, such as growth- factor-mediated cell signaling, nutrient-transportor mediated nutrient uptake, neurotrophin transport in the axons of neurons and lipid metabolism (By simi [...] (207 aa) |
| | RIPK2 | Receptor-interacting serine/threonine-protein kinase 2; Serine/threonine/tyrosine kinase that plays an essential role in modulation of innate and adaptive immune responses. Upon stimulation by bacterial peptidoglycans, NOD1 and NOD2 are activated, oligomerize and recruit RIPK2 through CARD-CARD domains. (538 aa) |
| | PFN1 | Profilin; Belongs to the profilin family. (104 aa) |
| | CASP1 | Uncharacterized protein; Belongs to the peptidase C14A family. (418 aa) |
| | FLNA | Uncharacterized protein. (2617 aa) |
| | MYL9 | Myosin light chain 9. (172 aa) |
