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| | CD40LG | CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (261 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (955 aa) |
| | GNAI1 | G protein subunit alpha i1. (349 aa) |
| | IL10RB | Interleukin 10 receptor subunit beta. (384 aa) |
| | MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (606 aa) |
| | NOS2 | Nitric oxide synthase, inducible; Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S- nitrosylation of GAPDH implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in i [...] (1146 aa) |
| | PDPK1 | 3-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (325 aa) |
| | TLR4 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (839 aa) |
| | HLA-DQB2 | Major histocompatibility complex, class II, DQ beta 1. (305 aa) |
| | BCL2L1 | Bcl-X. (233 aa) |
| | BIRC7 | Baculoviral IAP repeat containing 7. (278 aa) |
| | TLR2 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (784 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (830 aa) |
| | LAMB3 | Laminin subunit beta 3. (1157 aa) |
| | LAMB2 | Laminin subunit beta 2. (1802 aa) |
| | TGFB2 | Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa) |
| | ALOX5 | Arachidonate 5-lipoxygenase. (674 aa) |
| | GNAI3 | G protein subunit alpha i3. (354 aa) |
| | JAK1 | Tyrosine-protein kinase. (1151 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | MAP2K6 | Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (334 aa) |
| | HLA-DPB1 | RLA class II histocompatibility antigen, DP beta chain. (253 aa) |
| | HLA-DRA | Integral membrane protein; Belongs to the MHC class II family. (255 aa) |
| | LAMA2 | Laminin subunit alpha 2. (3126 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1732 aa) |
| | LAMA3 | Laminin subunit alpha 3. (3340 aa) |
| | BIRC3 | Baculoviral IAP repeat containing 3. (591 aa) |
| | MAPK10 | Mitogen-activated protein kinase. (467 aa) |
| | STAT3 | Signal transducer and activator of transcription. (770 aa) |
| | TGFB3 | Transforming growth factor beta 3. (458 aa) |
| | HSPA2 | Heat shock protein family A (Hsp70) member 2; Belongs to the heat shock protein 70 family. (635 aa) |
| | TAB2 | TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (693 aa) |
| | PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (142 aa) |
| | PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1102 aa) |
| | LAMC1 | Laminin subunit gamma 1. (998 aa) |
| | IFNGR1 | Interferon gamma receptor 1. (471 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (381 aa) |
| | LAMB1 | Laminin subunit beta 1. (1736 aa) |
| | NFKBIA | NFKB inhibitor alpha. (314 aa) |
| | IL12B | Interleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (324 aa) |
| | G1TC56_RABIT | TGFb_propeptide domain-containing protein. (168 aa) |
| | JAK2 | Tyrosine-protein kinase. (1132 aa) |
| | LOC100354468 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | TAB1 | TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (504 aa) |
| | HLA-DMA | Major histocompatibility complex, class II, DM alpha; Belongs to the MHC class II family. (234 aa) |
| | LOC100341515 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | NFKBIB | NFKB inhibitor beta. (356 aa) |
| | CCR5 | C-C chemokine receptor type 5; Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation (By similarity). (352 aa) |
| | LOC100347922 | TIR domain-containing protein. (940 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | CYCS | Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | IL10 | Interleukin-10; Major immune regulatory cytokine that acts on many cells of the immune system where it has profound anti-inflammatory functions, limiting excessive tissue disruption caused by inflammation. Mechanistically, IL10 binds to its heterotetrameric receptor comprising IL10RA and IL10RB leading to JAK1 and STAT2-mediated phosphorylation of STAT3. In turn, STAT3 translocates to the nucleus where it drives expression of anti-inflammatory mediators. Targets antigen-presenting cells (APCs) such as macrophages and monocytes and inhibits their release of pro-inflammatory cytokines in [...] (304 aa) |
| | GNAI2 | G protein subunit alpha i2. (355 aa) |
| | LOC100353673 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (153 aa) |
| | LAMA1 | Laminin subunit alpha 1. (3030 aa) |
| | G1TUQ7_RABIT | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | LOC108178730 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | RLA-DMB | Ig-like domain-containing protein. (257 aa) |
| | LOC100357840 | Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (105 aa) |
| | PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (880 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | IRGM | Uncharacterized protein. (420 aa) |
| | IFNGR2 | Interferon gamma receptor 2. (449 aa) |
| | TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (552 aa) |
| | IL10RA | Interleukin 10 receptor subunit alpha. (540 aa) |
| | XIAP | RING-type domain-containing protein. (633 aa) |
| | HSPA8 | Uncharacterized protein. (917 aa) |
| | CIITA | Class II major histocompatibility complex transactivator. (1175 aa) |
| | IRAK1 | Interleukin 1 receptor associated kinase 1. (534 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (439 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (1057 aa) |
| | IRAK4 | Interleukin 1 receptor associated kinase 4. (464 aa) |
| | LOC103345451 | TGFb_propeptide domain-containing protein. (203 aa) |
| | MAPK12 | Mitogen-activated protein kinase. (416 aa) |
| | CD40 | Uncharacterized protein. (494 aa) |
| | MYD88 | Uncharacterized protein. (476 aa) |
| | BCL2 | BH4_2 domain-containing protein. (389 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (346 aa) |
| | ENSOCUP00000037329 | TGFb_propeptide domain-containing protein. (263 aa) |
| | STAT1 | Signal transducer and activator of transcription. (879 aa) |
| | HSPA1L | Heat shock protein family A (Hsp70) member 1 like. (414 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | LOC100349667 | Ig-like domain-containing protein. (292 aa) |
| | ENSOCUP00000044284 | TGFb_propeptide domain-containing protein. (260 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (686 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (472 aa) |
| | ENSOCUP00000046413 | MHC_II_beta domain-containing protein. (169 aa) |
| | HLA-DOB | Major histocompatibility complex, class II, DO beta. (265 aa) |
| | CASP9 | Caspase 9; Belongs to the peptidase C14A family. (466 aa) |
| | MAPK13 | Mitogen-activated protein kinase. (399 aa) |
| | PIK3R6 | Phosphoinositide-3-kinase regulatory subunit 6. (777 aa) |
| | CASP8 | DED domain-containing protein. (109 aa) |
