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| | CDK4 | Cyclin dependent kinase 4; Belongs to the protein kinase superfamily. (392 aa) |
| | COL1A1 | Collagen alpha-1(I) chain. (1348 aa) |
| | LAMC1 | Laminin subunit gamma 1. (998 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2547 aa) |
| | RHEB | Ras homolog, mTORC1 binding. (184 aa) |
| | COL4A1 | Collagen type IV alpha 1 chain. (1637 aa) |
| | ITGA5 | Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa) |
| | ATP6V0A4 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (834 aa) |
| | COL2A1 | Fibrillar collagen NC1 domain-containing protein. (1487 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (364 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (381 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | ATP6V1F | V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa) |
| | LOC100345250 | Uncharacterized protein. (461 aa) |
| | FOXO1 | Fork-head domain-containing protein. (613 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (557 aa) |
| | ATP6V0E2 | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa) |
| | PRKCI | Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (596 aa) |
| | ITGB5 | Integrin beta; Belongs to the integrin beta chain family. (799 aa) |
| | LAMB1 | Laminin subunit beta 1. (1736 aa) |
| | ATM | Serine-protein kinase ATM; Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a single immunoglobulin heavy chain allele to enforce clonality and mo [...] (3056 aa) |
| | FZD2 | Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (668 aa) |
| | TBPL2 | TATA-box binding protein like 2. (379 aa) |
| | MAML1 | Mastermind like transcriptional coactivator 1. (932 aa) |
| | ATP6V0A1 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (832 aa) |
| | CCND2 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (431 aa) |
| | APC | APC regulator of WNT signaling pathway. (2871 aa) |
| | COL9A2 | Collagen type IX alpha 2 chain. (561 aa) |
| | CCNA1 | Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (423 aa) |
| | TCF7 | Transcription factor 7. (319 aa) |
| | PPP2CA | Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform; PP2A is the major phosphatase for microtubule-associated proteins (MAPs). PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase. Cooperates with SGO2 to protect centromeric cohesin from separase- mediated cleavage in oocytes specifically during meiosis I. Activates RAF1 by dephosphorylating it at 'Ser-259' (By similarity). (309 aa) |
| | PARD6B | Par-6 family cell polarity regulator beta. (371 aa) |
| | WNT10A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (417 aa) |
| | CDKN1A | Uncharacterized protein. (231 aa) |
| | WNT2 | Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters (By similarity). (360 aa) |
| | ATP6V1H | V-type proton ATPase subunit H; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit H activates ATPase activity of the enzyme and couples ATPase activity to proton flow. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. (483 aa) |
| | EGF | Pro-epidermal growth factor; EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. (1198 aa) |
| | NOTCH4 | Uncharacterized protein. (1854 aa) |
| | HEY1 | Hes related family bHLH transcription factor with YRPW motif 1. (452 aa) |
| | PTGS2 | Prostaglandin G/H synthase 2; Converts arachidonate to prostaglandin H2 (PGH2), a committed step in prostanoid synthesis. Constitutively expressed in some tissues in physiological conditions, such as the endothelium, kidney and brain, and in pathological conditions, such as in cancer. PTGS2 is responsible for production of inflammatory prostaglandins. Up-regulation of PTGS2 is also associated with increased cell adhesion, phenotypic changes, resistance to apoptosis and tumor angiogenesis. In cancer cells, PTGS2 is a key step in the production of prostaglandin E2 (PGE2), which plays imp [...] (604 aa) |
| | PPP2R1A | Protein phosphatase 2 scaffold subunit Aalpha. (542 aa) |
| | DLG3 | Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa) |
| | ATP6AP1 | Uncharacterized protein. (470 aa) |
| | ITGA11 | Integrin subunit alpha 11; Belongs to the integrin alpha chain family. (1151 aa) |
| | TLR3 | TIR domain-containing protein; Belongs to the Toll-like receptor family. (867 aa) |
| | EIF4EBP1 | Eukaryotic translation initiation factor 4E binding protein 1. (118 aa) |
| | TNR | Tenascin R. (1359 aa) |
| | BCAP31 | B cell receptor associated protein 31. (246 aa) |
| | LOC100346323 | Uncharacterized protein. (240 aa) |
| | IFNAR2 | Uncharacterized protein. (523 aa) |
| | FZD9 | Frizzled class receptor 9; Belongs to the G-protein coupled receptor Fz/Smo family. (560 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (397 aa) |
| | MX1 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa) |
| | LOC100355669 | Uncharacterized protein. (190 aa) |
| | LOC100354654 | Uncharacterized protein. (189 aa) |
| | UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (881 aa) |
| | FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (587 aa) |
| | MX2 | Dynamin-type G domain-containing protein; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (555 aa) |
| | LOC100357194 | Uncharacterized protein. (189 aa) |
| | TADA3 | Transcriptional adaptor 3. (432 aa) |
| | TRADD | TNFRSF1A associated via death domain. (447 aa) |
| | WNT6 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (338 aa) |
| | NRAS | NRAS proto-oncogene, GTPase. (189 aa) |
| | SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa) |
| | FZD7 | Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (575 aa) |
| | CCNA2 | Cyclin A2; Belongs to the cyclin family. (424 aa) |
| | CHD4 | Uncharacterized protein. (1940 aa) |
| | LAMA1 | Laminin subunit alpha 1. (3030 aa) |
| | IFNB1 | Interferon beta 1. (180 aa) |
| | COL6A5 | Collagen type VI alpha 5 chain. (2611 aa) |
| | PPP2R2D | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (521 aa) |
| | PIK3CD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa) |
| | TNC | Tenascin C. (2384 aa) |
| | TBP | TATA-box binding protein. (323 aa) |
| | PPP2R5B | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; As the regulatory component of the serine/threonine-protein phosphatase 2A (PP2A) holoenzyme, modulates substrate specificity, subcellular localization, and responsiveness to phosphorylation. The phosphorylated form mediates the interaction between PP2A and AKT1, leading to AKT1 dephosphorylation. (434 aa) |
| | SPP1 | Osteopontin; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction; Belongs to the osteopontin family. (311 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa) |
| | HES1 | Hes family bHLH transcription factor 1. (279 aa) |
| | ATP6V1G2 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (158 aa) |
| | LLGL2 | LLGL scribble cell polarity complex component 2. (1009 aa) |
| | WNT9A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (538 aa) |
| | WNT16 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (365 aa) |
| | COL4A5 | Collagen type IV alpha 5 chain. (1691 aa) |
| | NFKB1 | Nuclear factor kappa B subunit 1. (968 aa) |
| | VWF | Von Willebrand factor. (2788 aa) |
| | HES3 | BHLH domain-containing protein. (170 aa) |
| | VTN | Vitronectin; Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway. (475 aa) |
| | WNT1 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (370 aa) |
| | FZD3 | Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (603 aa) |
| | ATP6V1G1 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (162 aa) |
| | CDC42-2 | Uncharacterized protein. (222 aa) |
| | FZD8 | G_PROTEIN_RECEP_F2_4 domain-containing protein; Belongs to the G-protein coupled receptor Fz/Smo family. (303 aa) |
| | PIK3CA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa) |
| | BAK1 | BCL2 antagonist/killer 1. (210 aa) |
| | WNT7A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | OASL-2 | Uncharacterized protein. (538 aa) |
| | OASL | 2'-5'-oligoadenylate synthetase like. (603 aa) |
| | HEY2 | Hes related family bHLH transcription factor with YRPW motif 2. (338 aa) |
| | ITGA9 | Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (597 aa) |
| | ATP6V1C2 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (437 aa) |
| | DLG2 | Discs large MAGUK scaffold protein 2. (1011 aa) |
| | ITGA7 | Integrin subunit alpha 7; Belongs to the integrin alpha chain family. (1181 aa) |
| | PPP2R5C | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. The PP2A- PPP2R5C holoenzyme may activate TP53 and play a role in DNA damage- induced inhibition of cell proliferation. PP2A-PPP2R5C may also regulate the ERK signaling pathway through ERK dephosphorylation (By similarity). (542 aa) |
| | PPP2R2B | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (509 aa) |
| | MAP2K1 | Dual specificity mitogen-activated protein kinase kinase 1; Dual specificity protein kinase which acts as an essential component of the MAP kinase signal transduction pathway. Binding of extracellular ligands such as growth factors, cytokines and hormones to their cell-surface receptors activates RAS and this initiates RAF1 activation. RAF1 then further activates the dual-specificity protein kinases MAP2K1/MEK1 and MAP2K2/MEK2. Both MAP2K1/MEK1 and MAP2K2/MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine resid [...] (396 aa) |
| | ISG15 | ISG15 ubiquitin like modifier. (164 aa) |
| | ITGB6 | Integrin beta; Belongs to the integrin beta chain family. (787 aa) |
| | ITGA2 | Integrin subunit alpha 2; Belongs to the integrin alpha chain family. (1202 aa) |
| | ATP6V0A2 | V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (628 aa) |
| | RBPJ | Recombination signal binding protein for immunoglobulin kappa J region. (499 aa) |
| | CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (1057 aa) |
| | ITGB3 | Integrin beta; Belongs to the integrin beta chain family. (873 aa) |
| | ATP6V1D | V-type proton ATPase subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in cilium biogenesis through regulation of the transport and the localization of proteins to the cilium (By similarity). (259 aa) |
| | CREB3 | cAMP responsive element binding protein 3. (377 aa) |
| | WNT3 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa) |
| | FAS | Uncharacterized protein. (484 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | PPP2R2A | Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (447 aa) |
| | CREB5 | cAMP responsive element binding protein 5. (526 aa) |
| | TBK1 | TANK binding kinase 1. (836 aa) |
| | NOTCH2 | Notch receptor 2. (2481 aa) |
| | RAF1 | Raf-1 proto-oncogene, serine/threonine kinase. (701 aa) |
| | CASP3 | Caspase-3 subunit p12; Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Triggers cell adhesion in sympathetic neurons through RET cleavage (By similarity); Belongs to the peptidase C14A family. (346 aa) |
| | PPP2R5A | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (495 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (550 aa) |
| | PPP2R3A | Protein phosphatase 2 regulatory subunit B''alpha. (1143 aa) |
| | PTK2-2 | FERM_N_2 domain-containing protein. (121 aa) |
| | TSC1 | Uncharacterized protein. (988 aa) |
| | ITGAV | Integrin subunit alpha V; Belongs to the integrin alpha chain family. (1047 aa) |
| | CDK6 | Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (349 aa) |
| | STAT1 | Signal transducer and activator of transcription. (879 aa) |
| | STAT2 | STAT_int domain-containing protein. (205 aa) |
| | CREB3L2 | cAMP responsive element binding protein 3 like 2. (584 aa) |
| | WNT5B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (469 aa) |
| | RB1 | RB transcriptional corepressor 1. (943 aa) |
| | AKT3 | Non-specific serine/threonine protein kinase. (511 aa) |
| | MAGI1 | Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1358 aa) |
| | PPP2R1B | Protein phosphatase 2 scaffold subunit Abeta. (714 aa) |
| | GRB2 | Growth factor receptor bound protein 2. (278 aa) |
| | LOC100355380 | Ig-like domain-containing protein; Belongs to the MHC class I family. (445 aa) |
| | FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (537 aa) |
| | ITGB8 | Integrin beta-8; Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin (By similarity). It recognizes the sequence R-G-D in its ligands (By similarity). Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta- 1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (By similarity). Required during vasculogenesis (By similarity). (772 aa) |
| | CASP8 | DED domain-containing protein. (109 aa) |
| | PRKACB | Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily. (398 aa) |
| | COL4A6 | Collagen type IV alpha 6 chain. (1780 aa) |
| | IKBKG | Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (686 aa) |
| | PPP2R3B | EF-hand domain-containing protein. (577 aa) |
| | LOC100352479 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (332 aa) |
| | TNFRSF1A | TNF receptor superfamily member 1A. (472 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (431 aa) |
| | LOC100349085 | Ig-like domain-containing protein; Belongs to the MHC class I family. (418 aa) |
| | ITGA8 | Integrin subunit alpha 8; Belongs to the integrin alpha chain family. (1100 aa) |
| | MPP5 | Membrane palmitoylated protein 5; Belongs to the MAGUK family. (698 aa) |
| | PARD3 | Par-3 family cell polarity regulator. (1340 aa) |
| | IRF1 | Interferon regulatory factor. (336 aa) |
| | IFNAR1 | Interferon alpha and beta receptor subunit 1. (541 aa) |
| | WNT3A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (400 aa) |
| | GNAS | GNAS complex locus. (977 aa) |
| | ATP6V1C1 | V-type proton ATPase subunit C; Subunit of the peripheral V1 complex of vacuolar ATPase. Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (387 aa) |
| | COL4A3 | Collagen type IV alpha 3 chain. (1494 aa) |
| | ATP6V1G3 | V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (118 aa) |
| | UBR4 | Ubiquitin protein ligase E3 component n-recognin 4. (5180 aa) |
| | WNT5A | Protein Wnt-5a; Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta- catenin-induced reporter gene expression (By similarity). Suppression of the canonical pathway allows chondrogenesis to occur. Inhibits tumor formation. Stimulates cell migration. Decrease [...] (380 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (955 aa) |
| | COL6A2 | Uncharacterized protein. (425 aa) |
| | HEYL | Hes related family bHLH transcription factor with YRPW motif like. (301 aa) |
| | PTGER4 | Prostaglandin E2 receptor EP4 subtype; Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function. (488 aa) |
| | WNT8B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (351 aa) |
| | ATP6V1B2 | Vacuolar proton pump subunit B; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase; Belongs to the ATPase alpha/beta chains family. (511 aa) |
| | IBSP | Integrin binding sialoprotein. (309 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. Its pro-apoptotic activity is activated via its intera [...] (391 aa) |
| | ITGB7 | Integrin beta; Belongs to the integrin beta chain family. (798 aa) |
| | PPP2R5D | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. (553 aa) |
| | WNT11 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa) |
| | PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1147 aa) |
| | ATR | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2643 aa) |
| | COL6A6 | Collagen type VI alpha 6 chain. (2248 aa) |
| | LOC100353390 | Uncharacterized protein. (189 aa) |
| | JAG1 | Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa) |
| | ITGA10 | Integrin subunit alpha 10; Belongs to the integrin alpha chain family. (1169 aa) |
| | LOC100353390-2 | Uncharacterized protein. (190 aa) |
| | ITGA2B | Integrin_alpha2 domain-containing protein; Belongs to the integrin alpha chain family. (1008 aa) |
| | MFNG | MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase. (360 aa) |
| | PPP2R5E | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment; Belongs to the phosphatase 2A regulatory subunit B56 family. (467 aa) |
| | ITGB1 | Integrin beta; Belongs to the integrin beta chain family. (830 aa) |
| | TRAF3 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (568 aa) |
| | THBS1 | Thrombospondin 1. (1171 aa) |
| | LAMB3 | Laminin subunit beta 3. (1157 aa) |
| | CREBBP | CREB binding protein. (2403 aa) |
| | PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa) |
| | LAMB2 | Laminin subunit beta 2. (1802 aa) |
| | PIK3R1 | Phosphoinositide-3-kinase regulatory subunit 1. (724 aa) |
| | WNT8A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa) |
| | CCNE2 | Cyclin E2; Belongs to the cyclin family. (405 aa) |
| | CREB1 | cAMP responsive element binding protein 1. (341 aa) |
| | PPP2R3C | Protein phosphatase 2 regulatory subunit B''gamma. (453 aa) |
| | RBL1 | RB transcriptional corepressor like 1. (1068 aa) |
| | ATP6V0B | ATPase H+ transporting V0 subunit b; Belongs to the V-ATPase proteolipid subunit family. (283 aa) |
| | SOS2 | SOS Ras/Rho guanine nucleotide exchange factor 2. (1321 aa) |
| | ATP6V0E1 | V-type proton ATPase subunit; Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (81 aa) |
| | PSMC1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | JAK1 | Tyrosine-protein kinase. (1151 aa) |
| | RBL2 | RB transcriptional corepressor like 2. (1140 aa) |
| | BAX | BCL2 associated X, apoptosis regulator. (192 aa) |
| | G1SR88_RABIT | Ig-like domain-containing protein; Belongs to the MHC class I family. (264 aa) |
| | TNF | Tumor necrosis factor, membrane form; Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation (By similarity). Induces insulin resistance in adipocytes via inhibition of insulin-induced IRS1 tyrosine phosphorylation and insulin-induced glucose uptake. Induces [...] (234 aa) |
| | ATP6V1E1 | ATPase H+ transporting V1 subunit E1. (226 aa) |
| | TNXB | Uncharacterized protein. (862 aa) |
| | TBPL1 | Uncharacterized protein. (363 aa) |
| | ATP6V0C | V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (265 aa) |
| | IKBKB | Inhibitor of nuclear factor kappa B kinase subunit beta. (756 aa) |
| | EIF2AK2 | Interferon-induced double-stranded RNA-activated protein kinase. (547 aa) |
| | COL4A4 | Collagen alpha-4(IV) chain; Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. (1687 aa) |
| | COL6A3 | Uncharacterized protein. (562 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | NFX1 | Nuclear transcription factor, X-box binding 1. (1079 aa) |
| | PARD6A | Par-6 family cell polarity regulator alpha. (346 aa) |
| | RELN | Uncharacterized protein. (1813 aa) |
| | FZD6 | Frizzled class receptor 6; Belongs to the G-protein coupled receptor Fz/Smo family. (712 aa) |
| | THBS4 | Thrombospondin 4. (997 aa) |
| | MAML3 | Mastermind like transcriptional coactivator 3. (1124 aa) |
| | LAMA2 | Laminin subunit alpha 2. (3126 aa) |
| | SLC35E3 | Uncharacterized protein. (767 aa) |
| | WNT10B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (389 aa) |
| | LAMA4 | Laminin subunit alpha 4. (1732 aa) |
| | LAMA3 | Laminin subunit alpha 3. (3340 aa) |
| | THBS3 | Thrombospondin 3. (911 aa) |
| | FN1 | Fibronectin; Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization. Participates in the regulation of type I collagen deposition by osteoblasts (By similarity). (2427 aa) |
| | ATP6V0D2 | V-type proton ATPase subunit; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. Belongs to the V-ATPase V0D/AC39 subunit family. (350 aa) |
| | DLG1 | Discs large MAGUK scaffold protein 1; Belongs to the MAGUK family. (927 aa) |
| | EGFR | Receptor protein-tyrosine kinase. (1193 aa) |
| | MAML2 | Mastermind like transcriptional coactivator 2. (1137 aa) |
| | ITGA1 | Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1178 aa) |
| | EP300 | E1A binding protein p300. (2418 aa) |
| | VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (398 aa) |
| | CREB3L4 | cAMP responsive element binding protein 3 like 4. (395 aa) |
| | ATP6V0D1 | ATPase H+ transporting V0 subunit d1. (541 aa) |
| | KRAS | KRAS proto-oncogene, GTPase. (189 aa) |
| | COL1A2 | Collagen alpha-2(I) chain; Type I collagen is a member of group I collagen (fibrillar forming collagen); Belongs to the fibrillar collagen family. (1364 aa) |
| | COL9A1 | Collagen type IX alpha 1 chain. (921 aa) |
