(33 nodes) Receptor signaling pathway via STAT, and Long hematopoietin receptor, soluble alpha chain, conserved site network (Tetraodon nigroviridis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	H3BVT4_TETNG	Uncharacterized protein. (798 aa)
	SOCS1	Suppressor of cytokine signaling 1 variant 1. (220 aa)
	H3C1X4_TETNG	Suppressor of cytokine signaling 3a. (201 aa)
	H3C521_TETNG	Tumor protein p53 binding protein, 2a. (1104 aa)
	H3C641_TETNG	Interleukin 11a. (200 aa)
	CRFA3	Class I helical cytokine receptor member 3. (250 aa)
	H3C7E1_TETNG	Uncharacterized protein. (366 aa)
	CRFA21	Class I helical cytokine receptor number 21. (528 aa)
	CRFA25	Class I helical cytokine receptor number 25. (813 aa)
	CRFA26	Class I helical cytokine receptor number 26. (870 aa)
	H3C837_TETNG	Tyrosine-protein kinase. (1011 aa)
	H3C9U7_TETNG	IRF tryptophan pentad repeat domain-containing protein. (289 aa)
	H3CCE6_TETNG	AAA domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (392 aa)
	H3CGU9_TETNG	Suppressor of cytokine signaling 3. (213 aa)
	H3CH80_TETNG	Tyrosine-protein kinase. (1139 aa)
	H3CHJ3_TETNG	Uncharacterized protein. (332 aa)
	H3CK24_TETNG	AAA domain-containing protein. (380 aa)
	Q4SV14_TETNG	Chromosome undetermined SCAF13826, whole genome shotgun sequence. (51 aa)
	H3CPB0_TETNG	Interleukin 10. (184 aa)
	H3CTG4_TETNG	Interferon regulatory factor 9. (337 aa)
	H3CXH8_TETNG	Tyrosine-protein kinase. (1098 aa)
	H3D2B9_TETNG	Signal transducer and activator of transcription 3 (acute-phase response factor). (321 aa)
	H3D2C0_TETNG	Signal transducer and activator of transcription. (785 aa)
	H3DAR7_TETNG	Signal transducer and activator of transcription. (747 aa)
	H3DCB5_TETNG	Signal transducer and activator of transcription. (764 aa)
	H3DG19_TETNG	Protein phosphatase 1, regulatory subunit 13Bb. (1075 aa)
	H3DIF3_TETNG	Signal transducer and activator of transcription. (758 aa)
	H3DKH3_TETNG	Signal transducer and activator of transcription. (736 aa)
	H3DKH4_TETNG	Signal transducer and activator of transcription. (671 aa)
	H3DL74_TETNG	Tyrosine-protein kinase. (1162 aa)
	H3DMJ5_TETNG	Tyrosine kinase 2. (957 aa)
	H3DPE4_TETNG	Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (699 aa)
	STAT3	Signal transducer and activator of transcription 3. (290 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRFA21	CRFA25	ENSTNIP00000004165	ENSTNIP00000004169	Class I helical cytokine receptor number 21.	Class I helical cytokine receptor number 25.	0.566
CRFA21	CRFA26	ENSTNIP00000004165	ENSTNIP00000004170	Class I helical cytokine receptor number 21.	Class I helical cytokine receptor number 26.	0.965
CRFA21	H3BVT4_TETNG	ENSTNIP00000004165	ENSTNIP00000000096	Class I helical cytokine receptor number 21.	Uncharacterized protein.	0.694
CRFA21	H3C1X4_TETNG	ENSTNIP00000004165	ENSTNIP00000002241	Class I helical cytokine receptor number 21.	Suppressor of cytokine signaling 3a.	0.612
CRFA21	H3C641_TETNG	ENSTNIP00000004165	ENSTNIP00000003711	Class I helical cytokine receptor number 21.	Interleukin 11a.	0.784
CRFA21	H3C837_TETNG	ENSTNIP00000004165	ENSTNIP00000004409	Class I helical cytokine receptor number 21.	Tyrosine-protein kinase.	0.444
CRFA21	H3CCE6_TETNG	ENSTNIP00000004165	ENSTNIP00000005918	Class I helical cytokine receptor number 21.	AAA domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family.	0.524
CRFA21	H3CGU9_TETNG	ENSTNIP00000004165	ENSTNIP00000007477	Class I helical cytokine receptor number 21.	Suppressor of cytokine signaling 3.	0.612
CRFA21	H3CH80_TETNG	ENSTNIP00000004165	ENSTNIP00000007608	Class I helical cytokine receptor number 21.	Tyrosine-protein kinase.	0.444
CRFA21	H3CK24_TETNG	ENSTNIP00000004165	ENSTNIP00000008603	Class I helical cytokine receptor number 21.	AAA domain-containing protein.	0.524
CRFA21	H3CPB0_TETNG	ENSTNIP00000004165	ENSTNIP00000010093	Class I helical cytokine receptor number 21.	Interleukin 10.	0.495
CRFA21	H3CXH8_TETNG	ENSTNIP00000004165	ENSTNIP00000012963	Class I helical cytokine receptor number 21.	Tyrosine-protein kinase.	0.444
CRFA21	H3D2B9_TETNG	ENSTNIP00000004165	ENSTNIP00000014657	Class I helical cytokine receptor number 21.	Signal transducer and activator of transcription 3 (acute-phase response factor).	0.431
CRFA21	H3DAR7_TETNG	ENSTNIP00000004165	ENSTNIP00000017609	Class I helical cytokine receptor number 21.	Signal transducer and activator of transcription.	0.431
CRFA21	H3DIF3_TETNG	ENSTNIP00000004165	ENSTNIP00000020297	Class I helical cytokine receptor number 21.	Signal transducer and activator of transcription.	0.431
CRFA21	H3DKH3_TETNG	ENSTNIP00000004165	ENSTNIP00000021019	Class I helical cytokine receptor number 21.	Signal transducer and activator of transcription.	0.431
CRFA21	H3DL74_TETNG	ENSTNIP00000004165	ENSTNIP00000021272	Class I helical cytokine receptor number 21.	Tyrosine-protein kinase.	0.444
CRFA21	H3DMJ5_TETNG	ENSTNIP00000004165	ENSTNIP00000021743	Class I helical cytokine receptor number 21.	Tyrosine kinase 2.	0.444
CRFA21	Q4SV14_TETNG	ENSTNIP00000004165	ENSTNIP00000009182	Class I helical cytokine receptor number 21.	Chromosome undetermined SCAF13826, whole genome shotgun sequence.	0.431
CRFA21	STAT3	ENSTNIP00000004165	ENSTNIP00000022932	Class I helical cytokine receptor number 21.	Signal transducer and activator of transcription 3.	0.431