(55 nodes) Mixed, incl. RUNX1 regulates transcription of genes involved in differentiation of HSCs, and Pointed domain network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3BVW8_TETNG	Fli-1 proto-oncogene, ETS transcription factor b. (228 aa)
	H3BVZ1_TETNG	T-cell acute lymphocytic leukemia 1. (370 aa)
	H3BX30_TETNG	SH2B adaptor protein 3. (497 aa)
	H3BXD9_TETNG	Pax2_C domain-containing protein. (186 aa)
	H3BXP8_TETNG	Si:ch211-246m6.4. (119 aa)
	H3BZB7_TETNG	RUNX family transcription factor 1. (221 aa)
	H3C0I9_TETNG	Inhibitor of DNA binding 3. (123 aa)
	H3C201_TETNG	BHLH domain-containing protein. (46 aa)
	H3C2K3_TETNG	Runt-related transcription factor. (421 aa)
	H3C5X3_TETNG	Inhibitor of DNA binding 1, HLH protein. (141 aa)
	H3CED3_TETNG	LIM domain binding 1a. (404 aa)
	SSBP4	Single stranded DNA binding protein 4. (385 aa)
	H3CFM3_TETNG	Transcription factor 3b. (494 aa)
	H3CGY0_TETNG	Uncharacterized protein. (440 aa)
	H3CGZ5_TETNG	LIM-domain binding 1b. (346 aa)
	Q4SZT4_TETNG	Chromosome 2 SCAF11499, whole genome shotgun sequence. (218 aa)
	H3CIK8_TETNG	Uncharacterized protein. (406 aa)
	H3CKQ9_TETNG	Uncharacterized protein; Belongs to the tropomyosin family. (251 aa)
	H3CKU9_TETNG	BHLH domain-containing protein. (331 aa)
	H3CP48_TETNG	LIM domain only 3. (156 aa)
	H3CPE0_TETNG	GATA binding protein 1a. (417 aa)
	H3CRY0_TETNG	Musculin (activated B-cell factor-1). (145 aa)
	H3CRZ2_TETNG	ETS domain-containing protein. (118 aa)
	ISL2	Chromosome 13 SCAF14555, whole genome shotgun sequence. (360 aa)
	H3CUF1_TETNG	Paired box 8. (445 aa)
	H3CVA9_TETNG	Transcription factor 12. (695 aa)
	H3CVG1_TETNG	LIM domain only 1. (157 aa)
	H3CVJ3_TETNG	Spi-1 proto-oncogene b. (288 aa)
	H3CWW0_TETNG	Runt domain-containing protein. (301 aa)
	H3CXU1_TETNG	LIM homeobox 9. (361 aa)
	H3CY89_TETNG	Fli-1 proto-oncogene, ETS transcription factor a. (451 aa)
	H3CY90_TETNG	V-ets avian erythroblastosis virus E26 oncogene homolog 1. (440 aa)
	TCF4	Transcription factor 4. (531 aa)
	H3D0L5_TETNG	GATA binding protein 2a. (457 aa)
	ISL2-2	ISL LIM homeobox 2b. (362 aa)
	H3D1D9_TETNG	Achaete-scute family bHLH transcription factor 1b. (168 aa)
	H3D683_TETNG	LIM domain binding 2a. (328 aa)
	H3D864_TETNG	BHLH domain-containing protein. (510 aa)
	H3D8A4_TETNG	Uncharacterized protein. (159 aa)
	GATA2	Chromosome 11 SCAF14979, whole genome shotgun sequence. (456 aa)
	ALX3	ALX homeobox 3. (225 aa)
	ZNF521	Zinc finger protein 521. (1231 aa)
	H3DDH9_TETNG	LIM homeobox 4. (376 aa)
	H3DET1_TETNG	Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family. (1194 aa)
	H3DF36_TETNG	ALX homeobox 4b. (364 aa)
	H3DF37_TETNG	LIM domain only 2 (rhombotin-like 1). (159 aa)
	H3DFW9_TETNG	V-myb avian myeloblastosis viral oncogene homolog. (594 aa)
	H3DI34_TETNG	FEV transcription factor, ETS family member. (207 aa)
	H3DIJ5_TETNG	LisH domain-containing protein. (387 aa)
	H3DIV2_TETNG	Inhibitor of DNA binding 2a. (136 aa)
	Q4RKE8_TETNG	Chromosome 21 SCAF15029, whole genome shotgun sequence. (134 aa)
	H3DL03_TETNG	Tet methylcytosine dioxygenase 2. (795 aa)
	H3DMT3_TETNG	Uncharacterized protein. (163 aa)
	LHX3	LIM homeobox 3. (405 aa)
	ENSTNIP00000023027	LIM domain-binding protein 1. (74 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX3	ENSTNIP00000023027	ENSTNIP00000018185	ENSTNIP00000023027	ALX homeobox 3.	LIM domain-binding protein 1.	0.578
ALX3	H3CED3_TETNG	ENSTNIP00000018185	ENSTNIP00000006607	ALX homeobox 3.	LIM domain binding 1a.	0.578
ALX3	H3CGZ5_TETNG	ENSTNIP00000018185	ENSTNIP00000007523	ALX homeobox 3.	LIM-domain binding 1b.	0.578
ALX3	H3CVA9_TETNG	ENSTNIP00000018185	ENSTNIP00000012193	ALX homeobox 3.	Transcription factor 12.	0.479
ALX3	H3D1D9_TETNG	ENSTNIP00000018185	ENSTNIP00000014325	ALX homeobox 3.	Achaete-scute family bHLH transcription factor 1b.	0.477
ALX3	H3D683_TETNG	ENSTNIP00000018185	ENSTNIP00000016023	ALX homeobox 3.	LIM domain binding 2a.	0.578
ALX3	H3DDH9_TETNG	ENSTNIP00000018185	ENSTNIP00000018572	ALX homeobox 3.	LIM homeobox 4.	0.729
ALX3	H3DET1_TETNG	ENSTNIP00000018185	ENSTNIP00000019024	ALX homeobox 3.	Integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor), tandem duplicate 2; Belongs to the integrin alpha chain family.	0.571
ALX3	LHX3	ENSTNIP00000018185	ENSTNIP00000021913	ALX homeobox 3.	LIM homeobox 3.	0.729
ENSTNIP00000023027	ALX3	ENSTNIP00000023027	ENSTNIP00000018185	LIM domain-binding protein 1.	ALX homeobox 3.	0.578
ENSTNIP00000023027	GATA2	ENSTNIP00000023027	ENSTNIP00000017630	LIM domain-binding protein 1.	Chromosome 11 SCAF14979, whole genome shotgun sequence.	0.500
ENSTNIP00000023027	H3BVZ1_TETNG	ENSTNIP00000023027	ENSTNIP00000000153	LIM domain-binding protein 1.	T-cell acute lymphocytic leukemia 1.	0.867
ENSTNIP00000023027	H3BXP8_TETNG	ENSTNIP00000023027	ENSTNIP00000000761	LIM domain-binding protein 1.	Si:ch211-246m6.4.	0.414
ENSTNIP00000023027	H3BZB7_TETNG	ENSTNIP00000023027	ENSTNIP00000001333	LIM domain-binding protein 1.	RUNX family transcription factor 1.	0.540
ENSTNIP00000023027	H3C2K3_TETNG	ENSTNIP00000023027	ENSTNIP00000002471	LIM domain-binding protein 1.	Runt-related transcription factor.	0.412
ENSTNIP00000023027	H3CFM3_TETNG	ENSTNIP00000023027	ENSTNIP00000007050	LIM domain-binding protein 1.	Transcription factor 3b.	0.483
ENSTNIP00000023027	H3CKU9_TETNG	ENSTNIP00000023027	ENSTNIP00000008878	LIM domain-binding protein 1.	BHLH domain-containing protein.	0.561
ENSTNIP00000023027	H3CP48_TETNG	ENSTNIP00000023027	ENSTNIP00000010031	LIM domain-binding protein 1.	LIM domain only 3.	0.794
ENSTNIP00000023027	H3CPE0_TETNG	ENSTNIP00000023027	ENSTNIP00000010123	LIM domain-binding protein 1.	GATA binding protein 1a.	0.593
ENSTNIP00000023027	H3CRY0_TETNG	ENSTNIP00000023027	ENSTNIP00000011014	LIM domain-binding protein 1.	Musculin (activated B-cell factor-1).	0.414