(104 nodes) Mixed, incl. Homeobox domain, metazoa, and Homeobox KN domain network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3BWC6_TETNG	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (267 aa)
	H3BWZ3_TETNG	Homeobox B13a. (320 aa)
	H3BZT7_TETNG	Zinc finger E-box binding homeobox 1b. (960 aa)
	H3C2L6_TETNG	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (471 aa)
	LPIN2	Lipin 2. (891 aa)
	H3C575_TETNG	Homeobox B2a. (416 aa)
	H3C5U7_TETNG	Homeobox A11b. (286 aa)
	H3C6Z5_TETNG	Homeobox C10a. (352 aa)
	H3C790_TETNG	Homeobox domain-containing protein. (363 aa)
	H3C791_TETNG	Homeobox A4a. (417 aa)
	HOXA4	Homeobox A4. (257 aa)
	H3C793_TETNG	Homeobox A5a. (275 aa)
	H3C794_TETNG	Homeobox B3a. (479 aa)
	H3C795_TETNG	Homeobox B4a. (286 aa)
	H3C799_TETNG	Homeobox C4a. (265 aa)
	H3C7A0_TETNG	Homeobox C5a. (205 aa)
	H3C7A1_TETNG	Homeobox C6a. (236 aa)
	H3C7A2_TETNG	Homeobox C8a. (214 aa)
	H3C7A3_TETNG	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (263 aa)
	H3C7A4_TETNG	Homeobox D3a. (408 aa)
	H3C7A5_TETNG	Homeobox D4a. (235 aa)
	H3C7A7_TETNG	Homeobox domain-containing protein. (359 aa)
	H3C7A8_TETNG	Homeobox A11a. (281 aa)
	H3C7A9_TETNG	Homeobox A2b. (337 aa)
	H3C7B2_TETNG	Homeobox B5b. (279 aa)
	H3C7B3_TETNG	Homeobox B6b. (234 aa)
	H3C7B4_TETNG	Homeobox domain-containing protein. (372 aa)
	H3C7B5_TETNG	Homeobox C11a. (319 aa)
	H3C7B6_TETNG	Homeobox C12a. (277 aa)
	H3C7B8_TETNG	Homeobox D10a. (333 aa)
	H3C7C1_TETNG	Homeobox domain-containing protein. (249 aa)
	H3C7C2_TETNG	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (301 aa)
	H3C7C3_TETNG	Homeobox A10b. (327 aa)
	H3C7C5_TETNG	Homeobox domain-containing protein. (266 aa)
	Q4TAD6_TETNG	Chromosome 17 SCAF7369, whole genome shotgun sequence. (247 aa)
	H3CCF5_TETNG	Homeobox B1a. (396 aa)
	H3CE35_TETNG	Pre-B-cell leukemia homeobox 2. (401 aa)
	H3CEI1_TETNG	Homeobox domain-containing protein. (265 aa)
	H3CF45_TETNG	Pbx/knotted 1 homeobox 1.1. (446 aa)
	Q4T4U0_TETNG	Chromosome undetermined SCAF9550, whole genome shotgun sequence. (1195 aa)
	H3CFE8_TETNG	Homeobox domain-containing protein. (434 aa)
	H3CFX8_TETNG	Homeobox domain-containing protein. (364 aa)
	Q4T268_TETNG	Chromosome undetermined SCAF10325, whole genome shotgun sequence. (188 aa)
	Q4T265_TETNG	Chromosome undetermined SCAF10326, whole genome shotgun sequence. (228 aa)
	H3CHF0_TETNG	POU domain protein. (375 aa)
	H3CHF4_TETNG	Homeobox B8b. (98 aa)
	H3CHI2_TETNG	Homeobox domain-containing protein. (158 aa)
	H3CHI3_TETNG	Uncharacterized protein. (142 aa)
	H3CJ08_TETNG	Paired related homeobox 1a. (244 aa)
	H3CJ28_TETNG	Protein tweety homolog; Probable chloride channel; Belongs to the tweety family. (525 aa)
	H3CM41_TETNG	Pre-B-cell leukemia homeobox 1b. (322 aa)
	H3CNQ2_TETNG	NGFI-A binding protein 2 (EGR1 binding protein 2). (456 aa)
	H3CPU0_TETNG	SIX homeobox 2a. (289 aa)
	H3CPU1_TETNG	SIX homeobox 3a. (303 aa)
	H3CQ55_TETNG	Leucine-rich repeats and transmembrane domains 2a. (323 aa)
	H3CQQ9_TETNG	Short stature homeobox 2. (299 aa)
	H3CR17_TETNG	Mohawk homeobox b. (287 aa)
	H3CSV2_TETNG	Gastrulation brain homeobox 1. (320 aa)
	H3CT65_TETNG	Pbx/knotted 1 homeobox 2. (431 aa)
	Q4SKS6_TETNG	Chromosome undetermined SCAF14565, whole genome shotgun sequence. (403 aa)
	Q4SIW5_TETNG	Chromosome 21 SCAF14577, whole genome shotgun sequence. (301 aa)
	Q4SIN4_TETNG	Chromosome 21 SCAF14577, whole genome shotgun sequence. (368 aa)
	ALX4	ALX homeobox 4. (368 aa)
	E2F3	E2F transcription factor 3. (439 aa)
	H3CWD6_TETNG	T-box transcription factor 18. (523 aa)
	H3CWT3_TETNG	Meis homeobox 1 b. (245 aa)
	H3CWU5_TETNG	Orthodenticle homeobox 1. (323 aa)
	H3CXK4_TETNG	Homeobox domain-containing protein. (273 aa)
	H3CXK5_TETNG	Homeobox domain-containing protein. (274 aa)
	Q4SFD6_TETNG	Chromosome 2 SCAF14604, whole genome shotgun sequence. (284 aa)
	HMX1	Homeobox domain-containing protein. (133 aa)
	H3CZQ6_TETNG	Early growth response 3. (402 aa)
	Q4SCK5_TETNG	Chromosome undetermined SCAF14653, whole genome shotgun sequence. (317 aa)
	H3CZR4_TETNG	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (279 aa)
	H3D0R4_TETNG	Homeobox domain-containing protein. (294 aa)
	H3D330_TETNG	Hyperpolarization activated cyclic nucleotide-gated potassium channel 4. (1160 aa)
	H3D3B9_TETNG	Homeobox domain-containing protein. (260 aa)
	H3D3W5_TETNG	Family with sequence similarity 110 member C. (305 aa)
	Q4S5I2_TETNG	Chromosome 3 SCAF14730, whole genome shotgun sequence. (52 aa)
	H3D695_TETNG	Ladybird homeobox 2. (265 aa)
	H3D7U9_TETNG	Posterior neuron-specific homeobox. (133 aa)
	Q4S1Q2_TETNG	Chromosome 5 SCAF14766, whole genome shotgun sequence. (452 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (837 aa)
	H3DA70_TETNG	T-box transcription factor 4. (540 aa)
	H3DBC7_TETNG	Forkhead box J3. (578 aa)
	Q4RWE9_TETNG	Chromosome 2 SCAF14990, whole genome shotgun sequence. (162 aa)
	H3DCI2_TETNG	Retinol binding protein 7a, cellular; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (134 aa)
	H3DCP8_TETNG	PBC domain-containing protein. (98 aa)
	H3DCZ0_TETNG	One cut domain family member. (467 aa)
	H3DE90_TETNG	Tenomodulin. (257 aa)
	H3DFA1_TETNG	Homeobox protein. (315 aa)
	Q4RPQ9_TETNG	Chromosome 12 SCAF15007, whole genome shotgun sequence. (462 aa)
	H3DHT4_TETNG	Homeobox D11a. (273 aa)
	H3DHT5_TETNG	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (270 aa)
	H3DIG0_TETNG	Homeobox domain-containing protein. (346 aa)
	H3DIN3_TETNG	Meis homeobox 2a. (399 aa)
	H3DLM1_TETNG	Growth differentiation factor 11. (387 aa)
	Q4RHF6_TETNG	Chromosome 3 SCAF15050, whole genome shotgun sequence. (509 aa)
	EGR2	Early growth response 2. (248 aa)
	H3DMZ4_TETNG	Homeobox domain-containing protein. (241 aa)
	H3DNE4_TETNG	Uncharacterized protein. (271 aa)
	H3DP32_TETNG	Scleraxis bHLH transcription factor a. (213 aa)
	H3DPN6_TETNG	Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (297 aa)
	H3DPN7_TETNG	Paired box 9. (329 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALX4	H3CPU1_TETNG	ENSTNIP00000012256	ENSTNIP00000010274	ALX homeobox 4.	SIX homeobox 3a.	0.478
ALX4	H3DLM1_TETNG	ENSTNIP00000012256	ENSTNIP00000021419	ALX homeobox 4.	Growth differentiation factor 11.	0.461
E2F3	EGR2	ENSTNIP00000012496	ENSTNIP00000021859	E2F transcription factor 3.	Early growth response 2.	0.714
E2F3	H3DBC7_TETNG	ENSTNIP00000012496	ENSTNIP00000017819	E2F transcription factor 3.	Forkhead box J3.	0.654
E2F3	LPIN2	ENSTNIP00000012496	ENSTNIP00000003244	E2F transcription factor 3.	Lipin 2.	0.464
EGR2	E2F3	ENSTNIP00000021859	ENSTNIP00000012496	Early growth response 2.	E2F transcription factor 3.	0.714
EGR2	H3CZQ6_TETNG	ENSTNIP00000021859	ENSTNIP00000013742	Early growth response 2.	Early growth response 3.	0.902
EGR2	H3DBC7_TETNG	ENSTNIP00000021859	ENSTNIP00000017819	Early growth response 2.	Forkhead box J3.	0.647
EGR2	H3DFA1_TETNG	ENSTNIP00000021859	ENSTNIP00000019195	Early growth response 2.	Homeobox protein.	0.452
EGR2	LPIN2	ENSTNIP00000021859	ENSTNIP00000003244	Early growth response 2.	Lipin 2.	0.423
EGR2	Q4T265_TETNG	ENSTNIP00000021859	ENSTNIP00000007495	Early growth response 2.	Chromosome undetermined SCAF10326, whole genome shotgun sequence.	0.903
H3BWC6_TETNG	H3C790_TETNG	ENSTNIP00000000288	ENSTNIP00000004111	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox domain-containing protein.	0.470
H3BWC6_TETNG	H3C791_TETNG	ENSTNIP00000000288	ENSTNIP00000004112	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox A4a.	0.480
H3BWC6_TETNG	H3C799_TETNG	ENSTNIP00000000288	ENSTNIP00000004120	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox C4a.	0.415
H3BWC6_TETNG	H3C7A7_TETNG	ENSTNIP00000000288	ENSTNIP00000004128	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox domain-containing protein.	0.859
H3BWC6_TETNG	H3C7A9_TETNG	ENSTNIP00000000288	ENSTNIP00000004130	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox A2b.	0.450
H3BWC6_TETNG	H3C7C3_TETNG	ENSTNIP00000000288	ENSTNIP00000004144	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox A10b.	0.852
H3BWC6_TETNG	H3CE35_TETNG	ENSTNIP00000000288	ENSTNIP00000006509	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Pre-B-cell leukemia homeobox 2.	0.454
H3BWC6_TETNG	H3CFE8_TETNG	ENSTNIP00000000288	ENSTNIP00000006972	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Homeobox domain-containing protein.	0.454
H3BWC6_TETNG	H3CM41_TETNG	ENSTNIP00000000288	ENSTNIP00000009321	Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family.	Pre-B-cell leukemia homeobox 1b.	0.454