(33 nodes) Folate biosynthesis, and Melanin biosynthesis network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3BWX6_TETNG	GTP_cyclohydroI domain-containing protein. (164 aa)
	H3BZP5_TETNG	Dopachrome tautomerase. (519 aa)
	TPH1	Tryptophan hydroxylase 1 (tryptophan 5-monooxygenase) a. (485 aa)
	H3C4X2_TETNG	Premelanosome protein b. (708 aa)
	SLC45A4	Solute carrier family 45 member 4. (785 aa)
	H3CD74_TETNG	GTP cyclohydrolase 2. (244 aa)
	H3CJD0_TETNG	Tyrosinase_Cu-bd domain-containing protein. (419 aa)
	Q4SSZ9_TETNG	6-pyruvoyl tetrahydrobiopterin synthase. (148 aa)
	H3CNU1_TETNG	Sorbin and SH3 domain containing 2a. (650 aa)
	H3CPE5_TETNG	Transcription factor binding to IGHM enhancer 3b. (437 aa)
	H3CPI2_TETNG	Melanocyte inducing transcription factor a. (403 aa)
	Q4SQA7_TETNG	Chromosome 4 SCAF14533, whole genome shotgun sequence. (569 aa)
	H3CUG6_TETNG	Uncharacterized protein. (112 aa)
	H3CVW4_TETNG	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (513 aa)
	Q4SG74_TETNG	Chromosome 17 SCAF14597, whole genome shotgun sequence; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
	TYR	Tyrosinase. (540 aa)
	H3CXW2_TETNG	GTP_cyclohydroI domain-containing protein. (174 aa)
	TYRP1	Tyrosinase related protein 1. (529 aa)
	H3D3S4_TETNG	Alkaline phosphatase. (528 aa)
	MITF	Melanocyte inducing transcription factor b. (466 aa)
	H3D551_TETNG	Tyrosine hydroxylase 2. (472 aa)
	H3D552_TETNG	Phenylalanine hydroxylase. (459 aa)
	H3D682_TETNG	Quinoid dihydropteridine reductase a. (241 aa)
	ZSWIM6	Zinc finger SWIM-type containing 6. (793 aa)
	Q4RYZ7_TETNG	Alkaline phosphatase. (472 aa)
	H3DBD8_TETNG	Solute carrier family 45 member 1. (503 aa)
	PCBD2	Chromosome 7 SCAF15001, whole genome shotgun sequence. (137 aa)
	H3DJA1_TETNG	GTP cyclohydrolase I feedback regulator. (86 aa)
	H3DLL7_TETNG	Premelanosome protein a. (615 aa)
	H3DM08_TETNG	Solute carrier family 45 member 4b. (741 aa)
	Q4RGI4_TETNG	Chromosome undetermined SCAF15099, whole genome shotgun sequence. (217 aa)
	H3DQZ5_TETNG	Uncharacterized protein. (202 aa)
	SPR	Sepiapterin reductase. (270 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3BWX6_TETNG	H3CNU1_TETNG	ENSTNIP00000000489	ENSTNIP00000009924	GTP_cyclohydroI domain-containing protein.	Sorbin and SH3 domain containing 2a.	0.546
H3BWX6_TETNG	H3D682_TETNG	ENSTNIP00000000489	ENSTNIP00000016022	GTP_cyclohydroI domain-containing protein.	Quinoid dihydropteridine reductase a.	0.400
H3BWX6_TETNG	H3DJA1_TETNG	ENSTNIP00000000489	ENSTNIP00000020597	GTP_cyclohydroI domain-containing protein.	GTP cyclohydrolase I feedback regulator.	0.911
H3BWX6_TETNG	PCBD2	ENSTNIP00000000489	ENSTNIP00000019194	GTP_cyclohydroI domain-containing protein.	Chromosome 7 SCAF15001, whole genome shotgun sequence.	0.417
H3BWX6_TETNG	Q4SSZ9_TETNG	ENSTNIP00000000489	ENSTNIP00000009657	GTP_cyclohydroI domain-containing protein.	6-pyruvoyl tetrahydrobiopterin synthase.	0.872
H3BZP5_TETNG	H3CPI2_TETNG	ENSTNIP00000001461	ENSTNIP00000010165	Dopachrome tautomerase.	Melanocyte inducing transcription factor a.	0.719
H3BZP5_TETNG	H3CUG6_TETNG	ENSTNIP00000001461	ENSTNIP00000011900	Dopachrome tautomerase.	Uncharacterized protein.	0.469
H3BZP5_TETNG	H3CVW4_TETNG	ENSTNIP00000001461	ENSTNIP00000012398	Dopachrome tautomerase.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.626
H3BZP5_TETNG	H3DLL7_TETNG	ENSTNIP00000001461	ENSTNIP00000021415	Dopachrome tautomerase.	Premelanosome protein a.	0.687
H3BZP5_TETNG	MITF	ENSTNIP00000001461	ENSTNIP00000015533	Dopachrome tautomerase.	Melanocyte inducing transcription factor b.	0.548
H3BZP5_TETNG	Q4SQA7_TETNG	ENSTNIP00000001461	ENSTNIP00000010351	Dopachrome tautomerase.	Chromosome 4 SCAF14533, whole genome shotgun sequence.	0.609
H3BZP5_TETNG	TYRP1	ENSTNIP00000001461	ENSTNIP00000014259	Dopachrome tautomerase.	Tyrosinase related protein 1.	0.904
H3C4X2_TETNG	H3CJD0_TETNG	ENSTNIP00000003291	ENSTNIP00000008359	Premelanosome protein b.	Tyrosinase_Cu-bd domain-containing protein.	0.437
H3C4X2_TETNG	H3CUG6_TETNG	ENSTNIP00000003291	ENSTNIP00000011900	Premelanosome protein b.	Uncharacterized protein.	0.838
H3C4X2_TETNG	H3CVW4_TETNG	ENSTNIP00000003291	ENSTNIP00000012398	Premelanosome protein b.	Solute carrier family 24 member 5; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.466
H3C4X2_TETNG	TYR	ENSTNIP00000003291	ENSTNIP00000012844	Premelanosome protein b.	Tyrosinase.	0.805
H3CD74_TETNG	H3CNU1_TETNG	ENSTNIP00000006197	ENSTNIP00000009924	GTP cyclohydrolase 2.	Sorbin and SH3 domain containing 2a.	0.546
H3CD74_TETNG	H3CXW2_TETNG	ENSTNIP00000006197	ENSTNIP00000013097	GTP cyclohydrolase 2.	GTP_cyclohydroI domain-containing protein.	0.902
H3CD74_TETNG	H3D3S4_TETNG	ENSTNIP00000006197	ENSTNIP00000015162	GTP cyclohydrolase 2.	Alkaline phosphatase.	0.900
H3CD74_TETNG	H3D682_TETNG	ENSTNIP00000006197	ENSTNIP00000016022	GTP cyclohydrolase 2.	Quinoid dihydropteridine reductase a.	0.400