(29 nodes) Mixed, incl. NuRD complex, and Methyl-CpG binding protein 2/3, C-terminal domain network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3C0V6_TETNG	Uncharacterized protein. (1805 aa)
	H3C944_TETNG	GATA zinc finger domain containing 2B. (617 aa)
	H3C9P4_TETNG	Amino_oxidase domain-containing protein. (114 aa)
	H3CA65_TETNG	REST corepressor 1. (387 aa)
	H3CDI5_TETNG	MBD domain-containing protein. (265 aa)
	H3CFF7_TETNG	Chromodomain helicase DNA binding protein 5. (997 aa)
	H3CG45_TETNG	Metastasis associated 1 family, member 2. (665 aa)
	H3CHK5_TETNG	REST corepressor 3. (525 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (490 aa)
	H3CID8_TETNG	Metastasis associated 1 family, member 3. (578 aa)
	H3CKU8_TETNG	DUF1086 domain-containing protein. (70 aa)
	H3CLJ0_TETNG	RE1-silencing transcription factor. (859 aa)
	H3CRG9_TETNG	Uncharacterized protein. (1833 aa)
	H3CSR2_TETNG	High mobility group 20A. (294 aa)
	H3CV52_TETNG	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (440 aa)
	H3CZ55_TETNG	Methyl-CpG binding domain protein 3a. (274 aa)
	H3CZ58_TETNG	High mobility group 20B. (297 aa)
	H3D1Y3_TETNG	Amine oxidase. (524 aa)
	H3D637_TETNG	Chromodomain helicase DNA binding protein 3. (1911 aa)
	H3D6P2_TETNG	GATA zinc finger domain containing 2Ab. (639 aa)
	H3D8B6_TETNG	PHD finger protein 21Ab. (660 aa)
	H3D8I8_TETNG	REST corepressor 2. (528 aa)
	H3DCS2_TETNG	Autoimmune regulator. (548 aa)
	H3DCX8_TETNG	Uncharacterized protein. (639 aa)
	H3DCZ4_TETNG	Uncharacterized protein. (244 aa)
	H3DIP9_TETNG	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (840 aa)
	H3DPM5_TETNG	Metastasis associated 1. (551 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)
	H3DQL8_TETNG	CHDCT2 domain-containing protein. (294 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP2	H3C9P4_TETNG	ENSTNIP00000022625	ENSTNIP00000004966	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Amino_oxidase domain-containing protein.	0.451
CTBP2	H3CV52_TETNG	ENSTNIP00000022625	ENSTNIP00000012136	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
CTBP2	H3DIP9_TETNG	ENSTNIP00000022625	ENSTNIP00000020393	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.451
CTBP2	HDAC2	ENSTNIP00000022625	ENSTNIP00000007837	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
H3C0V6_TETNG	H3C944_TETNG	ENSTNIP00000001872	ENSTNIP00000004766	Uncharacterized protein.	GATA zinc finger domain containing 2B.	0.599
H3C0V6_TETNG	H3C9P4_TETNG	ENSTNIP00000001872	ENSTNIP00000004966	Uncharacterized protein.	Amino_oxidase domain-containing protein.	0.545
H3C0V6_TETNG	H3CA65_TETNG	ENSTNIP00000001872	ENSTNIP00000005137	Uncharacterized protein.	REST corepressor 1.	0.561
H3C0V6_TETNG	H3CDI5_TETNG	ENSTNIP00000001872	ENSTNIP00000006308	Uncharacterized protein.	MBD domain-containing protein.	0.600
H3C0V6_TETNG	H3CG45_TETNG	ENSTNIP00000001872	ENSTNIP00000007222	Uncharacterized protein.	Metastasis associated 1 family, member 2.	0.630
H3C0V6_TETNG	H3CHK5_TETNG	ENSTNIP00000001872	ENSTNIP00000007733	Uncharacterized protein.	REST corepressor 3.	0.561
H3C0V6_TETNG	H3CID8_TETNG	ENSTNIP00000001872	ENSTNIP00000008016	Uncharacterized protein.	Metastasis associated 1 family, member 3.	0.601
H3C0V6_TETNG	H3CLJ0_TETNG	ENSTNIP00000001872	ENSTNIP00000009119	Uncharacterized protein.	RE1-silencing transcription factor.	0.400
H3C0V6_TETNG	H3CV52_TETNG	ENSTNIP00000001872	ENSTNIP00000012136	Uncharacterized protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.549
H3C0V6_TETNG	H3CZ55_TETNG	ENSTNIP00000001872	ENSTNIP00000013540	Uncharacterized protein.	Methyl-CpG binding domain protein 3a.	0.600
H3C0V6_TETNG	H3CZ58_TETNG	ENSTNIP00000001872	ENSTNIP00000013543	Uncharacterized protein.	High mobility group 20B.	0.423
H3C0V6_TETNG	H3D1Y3_TETNG	ENSTNIP00000001872	ENSTNIP00000014521	Uncharacterized protein.	Amine oxidase.	0.482
H3C0V6_TETNG	H3D6P2_TETNG	ENSTNIP00000001872	ENSTNIP00000016183	Uncharacterized protein.	GATA zinc finger domain containing 2Ab.	0.599
H3C0V6_TETNG	H3D8B6_TETNG	ENSTNIP00000001872	ENSTNIP00000016757	Uncharacterized protein.	PHD finger protein 21Ab.	0.400
H3C0V6_TETNG	H3D8I8_TETNG	ENSTNIP00000001872	ENSTNIP00000016829	Uncharacterized protein.	REST corepressor 2.	0.561
H3C0V6_TETNG	H3DCX8_TETNG	ENSTNIP00000001872	ENSTNIP00000018371	Uncharacterized protein.	Uncharacterized protein.	0.599