(11 nodes) Mixed, incl. Telomeric repeat-containing RNA binding, and Protein decrotonylase activity network (Tetraodon nigroviridis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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experimentally determined

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gene neighborhood

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Your Input:
	H3C9P4_TETNG	Amino_oxidase domain-containing protein. (114 aa)
	H3CA65_TETNG	REST corepressor 1. (387 aa)
	H3CHK5_TETNG	REST corepressor 3. (525 aa)
	HDAC2	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (490 aa)
	H3CLJ0_TETNG	RE1-silencing transcription factor. (859 aa)
	H3CSR2_TETNG	High mobility group 20A. (294 aa)
	H3CV52_TETNG	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (440 aa)
	H3CZ58_TETNG	High mobility group 20B. (297 aa)
	H3D8B6_TETNG	PHD finger protein 21Ab. (660 aa)
	H3DIP9_TETNG	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family. (840 aa)
	CTBP2	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (441 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTBP2	H3C9P4_TETNG	ENSTNIP00000022625	ENSTNIP00000004966	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Amino_oxidase domain-containing protein.	0.451
CTBP2	H3CV52_TETNG	ENSTNIP00000022625	ENSTNIP00000012136	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
CTBP2	H3DIP9_TETNG	ENSTNIP00000022625	ENSTNIP00000020393	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.451
CTBP2	HDAC2	ENSTNIP00000022625	ENSTNIP00000007837	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.893
H3C9P4_TETNG	CTBP2	ENSTNIP00000004966	ENSTNIP00000022625	Amino_oxidase domain-containing protein.	C-terminal binding protein 2; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.	0.451
H3C9P4_TETNG	H3CA65_TETNG	ENSTNIP00000004966	ENSTNIP00000005137	Amino_oxidase domain-containing protein.	REST corepressor 1.	0.906
H3C9P4_TETNG	H3CHK5_TETNG	ENSTNIP00000004966	ENSTNIP00000007733	Amino_oxidase domain-containing protein.	REST corepressor 3.	0.864
H3C9P4_TETNG	H3CLJ0_TETNG	ENSTNIP00000004966	ENSTNIP00000009119	Amino_oxidase domain-containing protein.	RE1-silencing transcription factor.	0.812
H3C9P4_TETNG	H3CSR2_TETNG	ENSTNIP00000004966	ENSTNIP00000011296	Amino_oxidase domain-containing protein.	High mobility group 20A.	0.725
H3C9P4_TETNG	H3CV52_TETNG	ENSTNIP00000004966	ENSTNIP00000012136	Amino_oxidase domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.770
H3C9P4_TETNG	H3CZ58_TETNG	ENSTNIP00000004966	ENSTNIP00000013543	Amino_oxidase domain-containing protein.	High mobility group 20B.	0.922
H3C9P4_TETNG	H3D8B6_TETNG	ENSTNIP00000004966	ENSTNIP00000016757	Amino_oxidase domain-containing protein.	PHD finger protein 21Ab.	0.907
H3C9P4_TETNG	HDAC2	ENSTNIP00000004966	ENSTNIP00000007837	Amino_oxidase domain-containing protein.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.737
H3CA65_TETNG	H3C9P4_TETNG	ENSTNIP00000005137	ENSTNIP00000004966	REST corepressor 1.	Amino_oxidase domain-containing protein.	0.906
H3CA65_TETNG	H3CLJ0_TETNG	ENSTNIP00000005137	ENSTNIP00000009119	REST corepressor 1.	RE1-silencing transcription factor.	0.839
H3CA65_TETNG	H3CSR2_TETNG	ENSTNIP00000005137	ENSTNIP00000011296	REST corepressor 1.	High mobility group 20A.	0.575
H3CA65_TETNG	H3CV52_TETNG	ENSTNIP00000005137	ENSTNIP00000012136	REST corepressor 1.	Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.	0.771
H3CA65_TETNG	H3CZ58_TETNG	ENSTNIP00000005137	ENSTNIP00000013543	REST corepressor 1.	High mobility group 20B.	0.766
H3CA65_TETNG	H3D8B6_TETNG	ENSTNIP00000005137	ENSTNIP00000016757	REST corepressor 1.	PHD finger protein 21Ab.	0.763
H3CA65_TETNG	H3DIP9_TETNG	ENSTNIP00000005137	ENSTNIP00000020393	REST corepressor 1.	Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.	0.906