(95 nodes) Positive regulation of transmembrane transport network (Tetraodon nigroviridis)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	H3CFE1_TETNG	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (186 aa)
	H3BVT6_TETNG	Uncharacterized protein. (107 aa)
	H3BWI3_TETNG	Si:dkey-52j6.3. (328 aa)
	H3BWI9_TETNG	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (242 aa)
	H3BYQ3_TETNG	Si:dkey-194e6.1. (216 aa)
	H3BYW0_TETNG	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1273 aa)
	H3C147_TETNG	Uncharacterized protein. (535 aa)
	H3C163_TETNG	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (278 aa)
	H3C1E5_TETNG	Cytochrome c oxidase copper chaperone COX17. (69 aa)
	H3C1K0_TETNG	Endothelin receptor type Aa. (466 aa)
	H3C1V4_TETNG	R3H domain containing 2. (1069 aa)
	RAMP3	Receptor activity modifying protein 3. (165 aa)
	H3C502_TETNG	Uncharacterized protein. (184 aa)
	H3C5C3_TETNG	Uncharacterized protein. (63 aa)
	H3C631_TETNG	Uncharacterized protein. (173 aa)
	H3C7M0_TETNG	Uncharacterized protein. (323 aa)
	H3C8C9_TETNG	Uncharacterized protein. (1061 aa)
	H3C8R9_TETNG	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1241 aa)
	H3C8Z0_TETNG	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (239 aa)
	Q4TEP5_TETNG	Chromosome undetermined SCAF5205, whole genome shotgun sequence. (173 aa)
	H3C9D6_TETNG	Amino acid transporter. (485 aa)
	H3CAE8_TETNG	Opsin 3. (381 aa)
	H3CBN4_TETNG	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (325 aa)
	H3CCH1_TETNG	cAMP responsive element binding protein-like 2. (120 aa)
	H3CCM6_TETNG	Ion_trans domain-containing protein; Belongs to the potassium channel family. (338 aa)
	AMIGO3	Adhesion molecule with Ig like domain 3. (350 aa)
	H3CDZ8_TETNG	Phosphoinositide phospholipase C. (895 aa)
	H3CE48_TETNG	Uncharacterized protein. (114 aa)
	Q4T533_TETNG	Chromosome undetermined SCAF9444, whole genome shotgun sequence. (78 aa)
	Q4T278_TETNG	Chromosome undetermined SCAF10320, whole genome shotgun sequence. (162 aa)
	H3CIA9_TETNG	Antizyme inhibitor 1a; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (448 aa)
	H3CJR1_TETNG	Ig-like domain-containing protein. (500 aa)
	H3CLF7_TETNG	Stromal interaction molecule 1b. (503 aa)
	H3CLG9_TETNG	FATP synthase c subunit lysine N-methyltransferase. (208 aa)
	H3CM08_TETNG	Leucine rich repeat containing 38a. (273 aa)
	H3CM50_TETNG	Dopamine receptor D4a; Belongs to the G-protein coupled receptor 1 family. (374 aa)
	H3CM77_TETNG	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (615 aa)
	H3CNM1_TETNG	NDUFA4 mitochondrial complex associated like 2b. (84 aa)
	STAC3	SH3 and cysteine rich domain 3. (347 aa)
	H3CQ48_TETNG	Protein kinase domain-containing protein. (720 aa)
	H3CQX7_TETNG	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (279 aa)
	H3CQZ5_TETNG	LRRNT domain-containing protein. (301 aa)
	H3CRZ7_TETNG	Chemokine (C-X-C motif) receptor 3, tandem duplicate 3; Belongs to the G-protein coupled receptor 1 family. (372 aa)
	DRD4	Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (373 aa)
	H3CSU8_TETNG	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (232 aa)
	H3CSZ1_TETNG	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (384 aa)
	H3CT01_TETNG	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. (395 aa)
	Q4SJD6_TETNG	Chromosome 4 SCAF14575, whole genome shotgun sequence. (216 aa)
	H3CUN0_TETNG	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family. (356 aa)
	H3CUU9_TETNG	Antizyme inhibitor 1b; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (431 aa)
	H3CVU4_TETNG	Angiotensin-converting enzyme. (808 aa)
	H3CW35_TETNG	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (578 aa)
	H3CW43_TETNG	Amino acid transporter. (552 aa)
	H3CYD3_TETNG	R3H domain containing 1. (954 aa)
	H3D040_TETNG	Uncharacterized protein. (316 aa)
	H3D104_TETNG	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (424 aa)
	CACNG2	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (320 aa)
	H3D1D4_TETNG	Solute carrier family 1 member 2b. (576 aa)
	Q4S9I7_TETNG	Chromosome undetermined SCAF14696, whole genome shotgun sequence. (314 aa)
	STAC2	SH3 and cysteine rich domain 2. (365 aa)
	H3D2J0_TETNG	Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (256 aa)
	H3D377_TETNG	SH3 and cysteine rich domain 3. (335 aa)
	H3D3C4_TETNG	Huntingtin. (3115 aa)
	H3D3J0_TETNG	WNK lysine deficient protein kinase 1a. (617 aa)
	H3D3L9_TETNG	Solute carrier family 17 member 8. (584 aa)
	H3D3T0_TETNG	Leucine rich repeat containing 38b. (273 aa)
	H3D4B9_TETNG	Cytochrome c oxidase assembly factor 8. (147 aa)
	H3D4F5_TETNG	PTEN induced kinase 1. (562 aa)
	H3D5E9_TETNG	Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family. (784 aa)
	H3D630_TETNG	Stromal interaction molecule 2b. (664 aa)
	GCA	Grancalcin. (213 aa)
	H3D7N8_TETNG	Occludin a. (500 aa)
	H3D8U4_TETNG	PDZ domain containing 1. (521 aa)
	H3D9M0_TETNG	Zgc:153993. (182 aa)
	H3DAA9_TETNG	Protein kinase domain-containing protein. (180 aa)
	H3DAB0_TETNG	Uncharacterized protein. (296 aa)
	H3DB25_TETNG	WNK lysine deficient protein kinase 2. (1954 aa)
	NDUFA4	Chromosome 3 SCAF14987, whole genome shotgun sequence. (82 aa)
	WNK3	WNK lysine deficient protein kinase 3. (1670 aa)
	H3DCF0_TETNG	Adhesion molecule with Ig-like domain 1. (480 aa)
	H3DCW3_TETNG	Calpain 10; Belongs to the peptidase C2 family. (667 aa)
	H3DDA2_TETNG	Coagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family. (336 aa)
	Q4RTY1_TETNG	Chromosome 12 SCAF14996, whole genome shotgun sequence. (220 aa)
	RELN	Reelin. (3194 aa)
	H3DFQ2_TETNG	Stromal interaction molecule 1a. (658 aa)
	H3DH48_TETNG	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (557 aa)
	H3DHT7_TETNG	Nuclear factor, erythroid 2-like 2a. (599 aa)
	H3DHV5_TETNG	Uncharacterized protein. (466 aa)
	H3DIT6_TETNG	SH3 and cysteine rich domain. (413 aa)
	H3DKJ7_TETNG	Ig-like domain-containing protein. (420 aa)
	H3DMA7_TETNG	Anoctamin. (862 aa)
	H3DNB0_TETNG	Voltage-dependent calcium channel gamma-2 subunit; Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state; Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily. (323 aa)
	H3DNL4_TETNG	NADH:ubiquinone oxidoreductase subunit A4. (85 aa)
	H3DPG2_TETNG	C2 calcium dependent domain containing 5. (1012 aa)
	H3DPV7_TETNG	Calcineurin-like EF-hand protein 1. (194 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GCA	H3DCW3_TETNG	ENSTNIP00000016264	ENSTNIP00000018356	Grancalcin.	Calpain 10; Belongs to the peptidase C2 family.	0.417
H3C1K0_TETNG	H3CM77_TETNG	ENSTNIP00000002116	ENSTNIP00000009358	Endothelin receptor type Aa.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.488
H3C502_TETNG	H3DCW3_TETNG	ENSTNIP00000003321	ENSTNIP00000018356	Uncharacterized protein.	Calpain 10; Belongs to the peptidase C2 family.	0.417
H3C5C3_TETNG	H3DPG2_TETNG	ENSTNIP00000003442	ENSTNIP00000022411	Uncharacterized protein.	C2 calcium dependent domain containing 5.	0.583
H3C8C9_TETNG	H3D040_TETNG	ENSTNIP00000004501	ENSTNIP00000013876	Uncharacterized protein.	Uncharacterized protein.	0.578
H3CBN4_TETNG	H3CUN0_TETNG	ENSTNIP00000005656	ENSTNIP00000011964	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family.	0.906
H3CCM6_TETNG	H3CW35_TETNG	ENSTNIP00000005999	ENSTNIP00000012469	Ion_trans domain-containing protein; Belongs to the potassium channel family.	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	0.901
H3CLF7_TETNG	H3D5E9_TETNG	ENSTNIP00000009086	ENSTNIP00000015738	Stromal interaction molecule 1b.	Transient receptor potential cation channel, subfamily C, member 1; Belongs to the transient receptor (TC 1.A.4) family.	0.724
H3CM77_TETNG	H3C1K0_TETNG	ENSTNIP00000009358	ENSTNIP00000002116	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Endothelin receptor type Aa.	0.488
H3CM77_TETNG	H3D104_TETNG	ENSTNIP00000009358	ENSTNIP00000014190	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	0.488
H3CM77_TETNG	H3DDA2_TETNG	ENSTNIP00000009358	ENSTNIP00000018495	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor II (thrombin) receptor; Belongs to the G-protein coupled receptor 1 family.	0.978
H3CSU8_TETNG	H3DPG2_TETNG	ENSTNIP00000011332	ENSTNIP00000022411	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	C2 calcium dependent domain containing 5.	0.583
H3CSZ1_TETNG	H3CT01_TETNG	ENSTNIP00000011375	ENSTNIP00000011385	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.627
H3CSZ1_TETNG	H3DH48_TETNG	ENSTNIP00000011375	ENSTNIP00000019842	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.499
H3CT01_TETNG	H3CSZ1_TETNG	ENSTNIP00000011385	ENSTNIP00000011375	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	0.627
H3CT01_TETNG	H3DH48_TETNG	ENSTNIP00000011385	ENSTNIP00000019842	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel.	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	0.675
H3CUN0_TETNG	H3CBN4_TETNG	ENSTNIP00000011964	ENSTNIP00000005656	Apelin receptor b; Belongs to the G-protein coupled receptor 1 family.	Apelin receptor a; Belongs to the G-protein coupled receptor 1 family.	0.906
H3CW35_TETNG	H3CCM6_TETNG	ENSTNIP00000012469	ENSTNIP00000005999	Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family.	Ion_trans domain-containing protein; Belongs to the potassium channel family.	0.901
H3D040_TETNG	H3C8C9_TETNG	ENSTNIP00000013876	ENSTNIP00000004501	Uncharacterized protein.	Uncharacterized protein.	0.578
H3D104_TETNG	H3CM77_TETNG	ENSTNIP00000014190	ENSTNIP00000009358	Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.488