(28 nodes) Non-canonical Wnt signaling pathway network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

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co-expression

protein homology

Your Input:
	H3DMV1_TETNG	Receptor like tyrosine kinase. (554 aa)
	FZD7	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family. (567 aa)
	H3CNT3_TETNG	Secreted frizzled-related protein 2. (299 aa)
	H3CG66_TETNG	Vang-like protein. (590 aa)
	Q4SZI5_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (111 aa)
	H3CMU3_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
	H3BZ76_TETNG	FZ domain-containing protein. (124 aa)
	H3C3G0_TETNG	FZ domain-containing protein. (270 aa)
	Q4TCC7_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (58 aa)
	H3D0V4_TETNG	Uncharacterized protein. (544 aa)
	H3D0I7_TETNG	Dishevelled segment polarity protein 3a. (688 aa)
	H3CZ50_TETNG	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (524 aa)
	VANGL1	Vang-like protein. (528 aa)
	H3CXR9_TETNG	Dishevelled segment polarity protein 2. (740 aa)
	Q4SMQ6_TETNG	Chromosome 8 SCAF14545, whole genome shotgun sequence. (191 aa)
	H3CQI9_TETNG	Intraflagellar transport 80 homolog (Chlamydomonas). (777 aa)
	H3CPQ8_TETNG	Uncharacterized protein. (400 aa)
	VANGL2	Vang-like protein. (586 aa)
	H3CNY4_TETNG	Uncharacterized protein; Belongs to the G-protein coupled receptor Fz/Smo family. (299 aa)
	H3CB26_TETNG	Adhesion G protein-coupled receptor A3; Belongs to the G-protein coupled receptor 2 family. (1233 aa)
	WNT11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (191 aa)
	Q4RJT5_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	H3DMN4_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (363 aa)
	H3DP02_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
	H3D2B1_TETNG	Frizzled class receptor 2; Belongs to the G-protein coupled receptor Fz/Smo family. (549 aa)
	H3D4S3_TETNG	Dishevelled segment polarity protein 1a. (706 aa)
	PTK7	Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1066 aa)
	H3DC17_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (378 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FZD7	H3CMU3_TETNG	ENSTNIP00000006381	ENSTNIP00000009574	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.781
FZD7	H3CNT3_TETNG	ENSTNIP00000006381	ENSTNIP00000009916	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Secreted frizzled-related protein 2.	0.909
FZD7	H3CXR9_TETNG	ENSTNIP00000006381	ENSTNIP00000013054	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Dishevelled segment polarity protein 2.	0.466
FZD7	H3D0I7_TETNG	ENSTNIP00000006381	ENSTNIP00000014023	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Dishevelled segment polarity protein 3a.	0.944
FZD7	H3D0V4_TETNG	ENSTNIP00000006381	ENSTNIP00000014140	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Uncharacterized protein.	0.466
FZD7	H3D4S3_TETNG	ENSTNIP00000006381	ENSTNIP00000015512	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Dishevelled segment polarity protein 1a.	0.466
FZD7	H3DC17_TETNG	ENSTNIP00000006381	ENSTNIP00000018060	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.954
FZD7	H3DMN4_TETNG	ENSTNIP00000006381	ENSTNIP00000021782	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.644
FZD7	H3DP02_TETNG	ENSTNIP00000006381	ENSTNIP00000022251	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.781
FZD7	Q4RJT5_TETNG	ENSTNIP00000006381	ENSTNIP00000021096	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.781
FZD7	Q4SZI5_TETNG	ENSTNIP00000006381	ENSTNIP00000008134	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.548
FZD7	Q4TCC7_TETNG	ENSTNIP00000006381	ENSTNIP00000005017	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.548
FZD7	WNT11	ENSTNIP00000006381	ENSTNIP00000005592	Frizzled class receptor 7; Belongs to the G-protein coupled receptor Fz/Smo family.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.952
H3BZ76_TETNG	H3CMU3_TETNG	ENSTNIP00000001292	ENSTNIP00000009574	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.523
H3BZ76_TETNG	H3CXR9_TETNG	ENSTNIP00000001292	ENSTNIP00000013054	FZ domain-containing protein.	Dishevelled segment polarity protein 2.	0.509
H3BZ76_TETNG	H3D0I7_TETNG	ENSTNIP00000001292	ENSTNIP00000014023	FZ domain-containing protein.	Dishevelled segment polarity protein 3a.	0.466
H3BZ76_TETNG	H3D0V4_TETNG	ENSTNIP00000001292	ENSTNIP00000014140	FZ domain-containing protein.	Uncharacterized protein.	0.466
H3BZ76_TETNG	H3D4S3_TETNG	ENSTNIP00000001292	ENSTNIP00000015512	FZ domain-containing protein.	Dishevelled segment polarity protein 1a.	0.466
H3BZ76_TETNG	H3DC17_TETNG	ENSTNIP00000001292	ENSTNIP00000018060	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.599
H3BZ76_TETNG	H3DMN4_TETNG	ENSTNIP00000001292	ENSTNIP00000021782	FZ domain-containing protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.599