(37 nodes) Negative regulation of T cell activation network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3CT91_TETNG	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1930 aa)
	H3CVR1_TETNG	Membrane-associated ring finger (C3HC4) 7. (505 aa)
	H3CXL6_TETNG	T-box transcription factor 21. (470 aa)
	Q4S5E0_TETNG	Chromosome 19 SCAF14731, whole genome shotgun sequence. (240 aa)
	H3D538_TETNG	Uncharacterized protein. (51 aa)
	H3DAT9_TETNG	Si:ch211-157b11.8. (255 aa)
	H3DCT5_TETNG	Ring finger and CCCH-type domains 1b. (981 aa)
	H3DDY8_TETNG	V-set domain containing T cell activation inhibitor 1. (277 aa)
	H3DG27_TETNG	Si:ch211-203k16.3. (243 aa)
	H3DG53_TETNG	H2.0-like homeo box 1 (Drosophila). (359 aa)
	H3DJD6_TETNG	RIPOR family member 3. (939 aa)
	H3DK59_TETNG	Glycoprotein (transmembrane) nmb. (533 aa)
	H3DK94_TETNG	RHO family interacting cell polarization regulator 2. (1070 aa)
	H3DLM4_TETNG	E3 ubiquitin-protein ligase. (823 aa)
	H3DMC2_TETNG	Fibrinogen-like 2a. (424 aa)
	H3DMU9_TETNG	Arginase. (349 aa)
	H3DNV0_TETNG	Transforming growth factor beta; Belongs to the TGF-beta family. (382 aa)
	H3DPC8_TETNG	Tumor necrosis factor receptor superfamily, member 21. (610 aa)
	Q4RDU1_TETNG	Chromosome undetermined SCAF15699, whole genome shotgun sequence. (226 aa)
	H3DQK7_TETNG	Fibrinogen C-terminal domain-containing protein. (308 aa)
	H3BXR9_TETNG	Si:dkey-206d17.12. (523 aa)
	H3BXX0_TETNG	Leucine rich repeat containing 32. (441 aa)
	SOCS1	Suppressor of cytokine signaling 1 variant 1. (220 aa)
	H3C5Z1_TETNG	C2 domain-containing protein. (200 aa)
	IRF1	Interferon regulatory factor 1b. (226 aa)
	H3C8I1_TETNG	Ig-like domain-containing protein. (234 aa)
	H3CAT4_TETNG	Fibronectin type-III domain-containing protein. (126 aa)
	H3CD43_TETNG	Arginase. (322 aa)
	Q4T454_TETNG	Chromosome undetermined SCAF9816, whole genome shotgun sequence. (91 aa)
	H3CH79_TETNG	Ring finger and CCCH-type domains 2. (958 aa)
	H3CH82_TETNG	Uncharacterized protein. (287 aa)
	H3CHC0_TETNG	Galectin. (319 aa)
	H3CHI9_TETNG	Itchy E3 ubiquitin protein ligase b. (459 aa)
	H3CIQ8_TETNG	Transmembrane 131 like. (1546 aa)
	SDC4	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family. (226 aa)
	H3CND1_TETNG	Glomulin, FKBP associated protein a. (595 aa)
	H3CS51_TETNG	Mitotic arrest deficient 1 like 1. (719 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3BXR9_TETNG	H3DCT5_TETNG	ENSTNIP00000000782	ENSTNIP00000018328	Si:dkey-206d17.12.	Ring finger and CCCH-type domains 1b.	0.557
H3BXX0_TETNG	H3DNV0_TETNG	ENSTNIP00000000833	ENSTNIP00000022199	Leucine rich repeat containing 32.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.943
H3C5Z1_TETNG	H3CHI9_TETNG	ENSTNIP00000003661	ENSTNIP00000007717	C2 domain-containing protein.	Itchy E3 ubiquitin protein ligase b.	0.730
H3C5Z1_TETNG	Q4T454_TETNG	ENSTNIP00000003661	ENSTNIP00000007034	C2 domain-containing protein.	Chromosome undetermined SCAF9816, whole genome shotgun sequence.	0.445
H3C8I1_TETNG	H3CH82_TETNG	ENSTNIP00000004553	ENSTNIP00000007610	Ig-like domain-containing protein.	Uncharacterized protein.	0.479
H3CH79_TETNG	H3DCT5_TETNG	ENSTNIP00000007607	ENSTNIP00000018328	Ring finger and CCCH-type domains 2.	Ring finger and CCCH-type domains 1b.	0.645
H3CH82_TETNG	H3C8I1_TETNG	ENSTNIP00000007610	ENSTNIP00000004553	Uncharacterized protein.	Ig-like domain-containing protein.	0.479
H3CH82_TETNG	H3CHC0_TETNG	ENSTNIP00000007610	ENSTNIP00000007648	Uncharacterized protein.	Galectin.	0.493
H3CH82_TETNG	H3DDY8_TETNG	ENSTNIP00000007610	ENSTNIP00000018731	Uncharacterized protein.	V-set domain containing T cell activation inhibitor 1.	0.479
H3CHC0_TETNG	H3CH82_TETNG	ENSTNIP00000007648	ENSTNIP00000007610	Galectin.	Uncharacterized protein.	0.493
H3CHI9_TETNG	H3C5Z1_TETNG	ENSTNIP00000007717	ENSTNIP00000003661	Itchy E3 ubiquitin protein ligase b.	C2 domain-containing protein.	0.730
H3CHI9_TETNG	Q4T454_TETNG	ENSTNIP00000007717	ENSTNIP00000007034	Itchy E3 ubiquitin protein ligase b.	Chromosome undetermined SCAF9816, whole genome shotgun sequence.	0.861
H3CXL6_TETNG	H3DG53_TETNG	ENSTNIP00000013001	ENSTNIP00000019497	T-box transcription factor 21.	H2.0-like homeo box 1 (Drosophila).	0.563
H3DCT5_TETNG	H3BXR9_TETNG	ENSTNIP00000018328	ENSTNIP00000000782	Ring finger and CCCH-type domains 1b.	Si:dkey-206d17.12.	0.557
H3DCT5_TETNG	H3CH79_TETNG	ENSTNIP00000018328	ENSTNIP00000007607	Ring finger and CCCH-type domains 1b.	Ring finger and CCCH-type domains 2.	0.645
H3DDY8_TETNG	H3CH82_TETNG	ENSTNIP00000018731	ENSTNIP00000007610	V-set domain containing T cell activation inhibitor 1.	Uncharacterized protein.	0.479
H3DG53_TETNG	H3CXL6_TETNG	ENSTNIP00000019497	ENSTNIP00000013001	H2.0-like homeo box 1 (Drosophila).	T-box transcription factor 21.	0.563
H3DK59_TETNG	SDC4	ENSTNIP00000020905	ENSTNIP00000008668	Glycoprotein (transmembrane) nmb.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.547
H3DNV0_TETNG	H3BXX0_TETNG	ENSTNIP00000022199	ENSTNIP00000000833	Transforming growth factor beta; Belongs to the TGF-beta family.	Leucine rich repeat containing 32.	0.943
H3DNV0_TETNG	SDC4	ENSTNIP00000022199	ENSTNIP00000008668	Transforming growth factor beta; Belongs to the TGF-beta family.	Syndecan; Cell surface proteoglycan; Belongs to the syndecan proteoglycan family.	0.735