(17 nodes) Lung morphogenesis network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3CNK3_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (350 aa)
	H3CLW2_TETNG	TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (563 aa)
	H3CI64_TETNG	Dystroglycan 1. (774 aa)
	H3CB68_TETNG	MADS-box domain-containing protein. (500 aa)
	H3CAP3_TETNG	HPS1 biogenesis of lysosomal organelles complex 3 subunit 1. (713 aa)
	H3C9F4_TETNG	Uncharacterized protein. (137 aa)
	H3BZU8_TETNG	Sprouty RTK signaling antagonist 2. (277 aa)
	H3CNP4_TETNG	Cathepsin Z; Belongs to the peptidase C1 family. (306 aa)
	H3CT91_TETNG	Discs, large homolog 5a (Drosophila); Belongs to the MAGUK family. (1930 aa)
	H3D3R8_TETNG	Serine/threonine kinase 40. (435 aa)
	H3D694_TETNG	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family. (301 aa)
	H3D7C3_TETNG	Serum response factor b. (514 aa)
	TGFBR2	Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (517 aa)
	H3DC48_TETNG	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (386 aa)
	H3DK23_TETNG	Hedgehog interacting protein. (696 aa)
	H3DKJ9_TETNG	Peptidase S72 domain-containing protein. (876 aa)
	H3DPJ7_TETNG	Cathepsin H; Belongs to the peptidase C1 family. (330 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3CI64_TETNG	H3DKJ9_TETNG	ENSTNIP00000007942	ENSTNIP00000021045	Dystroglycan 1.	Peptidase S72 domain-containing protein.	0.901
H3CNP4_TETNG	H3DPJ7_TETNG	ENSTNIP00000009877	ENSTNIP00000022446	Cathepsin Z; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.483
H3D694_TETNG	H3DPJ7_TETNG	ENSTNIP00000016034	ENSTNIP00000022446	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	Cathepsin H; Belongs to the peptidase C1 family.	0.483
H3DKJ9_TETNG	H3CI64_TETNG	ENSTNIP00000021045	ENSTNIP00000007942	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.901
H3DPJ7_TETNG	H3CNP4_TETNG	ENSTNIP00000022446	ENSTNIP00000009877	Cathepsin H; Belongs to the peptidase C1 family.	Cathepsin Z; Belongs to the peptidase C1 family.	0.483
H3DPJ7_TETNG	H3D694_TETNG	ENSTNIP00000022446	ENSTNIP00000016034	Cathepsin H; Belongs to the peptidase C1 family.	Pept_C1 domain-containing protein; Belongs to the peptidase C1 family.	0.483