(59 nodes) Signaling by SCF-KIT network (Tetraodon nigroviridis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	H3CV34_TETNG	Growth factor receptor-bound protein 10a. (598 aa)
	H3D876_TETNG	Kit ligand a. (274 aa)
	H3DCD6_TETNG	Matrix metallopeptidase 9. (535 aa)
	GRB14	Chromosome 2 SCAF15004, whole genome shotgun sequence. (376 aa)
	YES1	Tyrosine-protein kinase. (550 aa)
	H3DIF3_TETNG	Signal transducer and activator of transcription. (758 aa)
	H3DIL2_TETNG	Tyrosine-protein kinase. (536 aa)
	H3DIL4_TETNG	Tyrosine-protein kinase. (469 aa)
	H3DJR0_TETNG	Tyrosine-protein kinase. (513 aa)
	H3DLN8_TETNG	Tyrosine-protein kinase. (543 aa)
	H3DMS7_TETNG	YES proto-oncogene 1, Src family tyrosine kinase. (232 aa)
	H3C8V0_TETNG	PI3K-RBD domain-containing protein; Belongs to the PI3/PI4-kinase family. (149 aa)
	H3C837_TETNG	Tyrosine-protein kinase. (1011 aa)
	H3C6E3_TETNG	Fibronectin type III domain containing 3A. (1220 aa)
	H3C5M3_TETNG	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (986 aa)
	H3C3C1_TETNG	Fibronectin type-III domain-containing protein. (356 aa)
	H3BZE4_TETNG	Protein tyrosine phosphatase receptor type Ua. (1404 aa)
	H3BYV0_TETNG	Tyrosine-protein kinase. (510 aa)
	H3BX30_TETNG	SH2B adaptor protein 3. (497 aa)
	H3DNG4_TETNG	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (729 aa)
	H3DNY4_TETNG	GRB2-associated binding protein 2. (673 aa)
	H3DP66_TETNG	Growth factor receptor-bound protein 10b. (425 aa)
	H3DQ93_TETNG	Uncharacterized protein. (307 aa)
	H3C9Q4_TETNG	Zgc:55558. (152 aa)
	H3CB06_TETNG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1066 aa)
	Q4T8G2_TETNG	Chromosome undetermined SCAF7799, whole genome shotgun sequence. (117 aa)
	H3CDU6_TETNG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (876 aa)
	H3CEB3_TETNG	Growth factor receptor-bound protein 2b. (153 aa)
	H3CEC8_TETNG	Uncharacterized protein. (378 aa)
	H3CEP5_TETNG	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (971 aa)
	H3CGC1_TETNG	GRB2 related adaptor protein b. (214 aa)
	H3CH80_TETNG	Tyrosine-protein kinase. (1139 aa)
	H3CIZ7_TETNG	MAM domain-containing protein. (99 aa)
	FYN	Tyrosine-protein kinase. (464 aa)
	H3CMG4_TETNG	Fibronectin type III domain containing 3Ba. (842 aa)
	H3CMT6_TETNG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (1070 aa)
	H3CNB1_TETNG	Uncharacterized protein. (459 aa)
	H3CP25_TETNG	Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (356 aa)
	H3CQS3_TETNG	Cbl proto-oncogene, E3 ubiquitin protein ligase. (892 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
	H3CRH0_TETNG	Protein tyrosine phosphatase non-receptor type 6. (584 aa)
	Q4S292_TETNG	Chromosome undetermined SCAF14764, whole genome shotgun sequence. (170 aa)
	H3CV78_TETNG	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (825 aa)
	H3CWB7_TETNG	Protein tyrosine phosphatase receptor type Ub. (1396 aa)
	H3CX90_TETNG	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (470 aa)
	H3CXW1_TETNG	Uncharacterized protein. (406 aa)
	H3CY46_TETNG	Uncharacterized protein. (835 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (261 aa)
	H3CZX7_TETNG	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (590 aa)
	H3D0H0_TETNG	Phosphoinositide-3-kinase, regulatory subunit 2 (beta). (731 aa)
	H3D2C0_TETNG	Signal transducer and activator of transcription. (785 aa)
	H3D2S5_TETNG	Growth factor receptor bound protein 7. (497 aa)
	Q4S7E9_TETNG	Chromosome 13 SCAF14715, whole genome shotgun sequence. (189 aa)
	H3D6U1_TETNG	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (828 aa)
	H3D112_TETNG	GRB2 related adaptor protein 2a. (325 aa)
	Q4SAD9_TETNG	Chromosome 13 SCAF14688, whole genome shotgun sequence. (189 aa)
	H3D217_TETNG	GRB2 related adaptor protein a. (216 aa)
	H3DQF3_TETNG	Tyrosine-protein kinase. (489 aa)
	Q4RBV9_TETNG	Chromosome undetermined SCAF20514, whole genome shotgun sequence. (102 aa)

Your Current Organism:

Tetraodon nigroviridis

NCBI taxonomy Id: 99883
Other names: T. nigroviridis, spotted green pufferfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSDE1	H3C8V0_TETNG	ENSTNIP00000013808	ENSTNIP00000004672	Cold shock domain containing E1, RNA-binding.	PI3K-RBD domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.404
CSDE1	H3CB06_TETNG	ENSTNIP00000013808	ENSTNIP00000005428	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.404
CSDE1	H3CDU6_TETNG	ENSTNIP00000013808	ENSTNIP00000006420	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.404
CSDE1	H3CEB3_TETNG	ENSTNIP00000013808	ENSTNIP00000006587	Cold shock domain containing E1, RNA-binding.	Growth factor receptor-bound protein 2b.	0.672
CSDE1	H3CMT6_TETNG	ENSTNIP00000013808	ENSTNIP00000009567	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.404
CSDE1	H3CP25_TETNG	ENSTNIP00000013808	ENSTNIP00000010008	Cold shock domain containing E1, RNA-binding.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.404
CSDE1	H3CRH0_TETNG	ENSTNIP00000013808	ENSTNIP00000010854	Cold shock domain containing E1, RNA-binding.	Protein tyrosine phosphatase non-receptor type 6.	0.487
CSDE1	H3CZX7_TETNG	ENSTNIP00000013808	ENSTNIP00000013813	Cold shock domain containing E1, RNA-binding.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.487
CSDE1	H3D876_TETNG	ENSTNIP00000013808	ENSTNIP00000016717	Cold shock domain containing E1, RNA-binding.	Kit ligand a.	0.431
CSDE1	PIK3CA	ENSTNIP00000013808	ENSTNIP00000010637	Cold shock domain containing E1, RNA-binding.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.404
FYN	H3CEB3_TETNG	ENSTNIP00000008433	ENSTNIP00000006587	Tyrosine-protein kinase.	Growth factor receptor-bound protein 2b.	0.550
FYN	H3CQS3_TETNG	ENSTNIP00000008433	ENSTNIP00000010607	Tyrosine-protein kinase.	Cbl proto-oncogene, E3 ubiquitin protein ligase.	0.490
FYN	H3CRH0_TETNG	ENSTNIP00000008433	ENSTNIP00000010854	Tyrosine-protein kinase.	Protein tyrosine phosphatase non-receptor type 6.	0.469
FYN	H3CV78_TETNG	ENSTNIP00000008433	ENSTNIP00000012162	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.403
FYN	H3CY46_TETNG	ENSTNIP00000008433	ENSTNIP00000013181	Tyrosine-protein kinase.	Uncharacterized protein.	0.490
FYN	H3CZX7_TETNG	ENSTNIP00000008433	ENSTNIP00000013813	Tyrosine-protein kinase.	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily.	0.469
FYN	H3D112_TETNG	ENSTNIP00000008433	ENSTNIP00000014198	Tyrosine-protein kinase.	GRB2 related adaptor protein 2a.	0.558
FYN	H3D2C0_TETNG	ENSTNIP00000008433	ENSTNIP00000014658	Tyrosine-protein kinase.	Signal transducer and activator of transcription.	0.436
FYN	Q4RBV9_TETNG	ENSTNIP00000008433	ENSTNIP00000022797	Tyrosine-protein kinase.	Chromosome undetermined SCAF20514, whole genome shotgun sequence.	0.490
FYN	Q4SAD9_TETNG	ENSTNIP00000008433	ENSTNIP00000014330	Tyrosine-protein kinase.	Chromosome 13 SCAF14688, whole genome shotgun sequence.	0.436