STRINGSTRING
AEA64970.1 AEA64970.1 AEA58816.1 AEA58816.1 argC argC argJ argJ AEA60142.1 AEA60142.1 AEA60144.1 AEA60144.1 AEA60158.1 AEA60158.1 AEA60166.1 AEA60166.1 AEA60587.1 AEA60587.1 AEA60951.1 AEA60951.1 ilvD ilvD AEA61043.1 AEA61043.1 AEA61265.1 AEA61265.1 argA argA leuA leuA ilvC ilvC AEA61555.1 AEA61555.1 AEA61556.1 AEA61556.1 AEA61645.1 AEA61645.1 ilvD-2 ilvD-2 argD-2 argD-2 AEA61835.1 AEA61835.1 AEA61836.1 AEA61836.1 AEA61847.1 AEA61847.1 leuA-2 leuA-2 argB argB ilvE ilvE AEA62960.1 AEA62960.1 argC-2 argC-2 AEA63583.1 AEA63583.1 leuD leuD leuC leuC AEA64255.1 AEA64255.1 leuB leuB leuD-2 leuD-2 leuC-2 leuC-2 AEA64263.1 AEA64263.1 AEA64274.1 AEA64274.1 AEA64657.1 AEA64657.1 AEA64839.1 AEA64839.1 AEA64860.1 AEA64860.1 AEA64900.1 AEA64900.1 AEA64950.1 AEA64950.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AEA64970.1Acetylornithine deacetylase. (392 aa)
AEA58816.1Acetolactate synthase, large subunit, putative; Belongs to the TPP enzyme family. (573 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (315 aa)
argJArginine biosynthesis protein ArgJ; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (413 aa)
AEA60142.1Diaminobutyrate/2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (418 aa)
AEA60144.1Acetolactate synthase, large subunit, biosynthetic type. (587 aa)
AEA60158.1Citrate synthase. (268 aa)
AEA60166.1Hypothetical protein. (534 aa)
AEA60587.1Bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Belongs to the aconitase/IPM isomerase family. (861 aa)
AEA60951.1Aminotransferase, classes I and II. (412 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (619 aa)
AEA61043.1Acetylornithine deacetylase. (406 aa)
AEA61265.1Aspartate kinase, monofunctional class; Belongs to the aspartokinase family. (416 aa)
argAAmino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. (455 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (513 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
AEA61555.1Acetolactate synthase III small subunit. (163 aa)
AEA61556.1Acetolactate synthase, large subunit, biosynthetic type. (610 aa)
AEA61645.1Aminotransferase family protein. (391 aa)
ilvD-2Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (557 aa)
argD-2Bifunctional N-succinyldiaminopimelate- aminotransferase/acetylornithine transaminase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (412 aa)
AEA61835.1Isocitrate dehydrogenase, NADP-dependent; Belongs to the monomeric-type IDH family. (742 aa)
AEA61836.1Isocitrate dehydrogenase. (417 aa)
AEA61847.1Citrate synthase. (418 aa)
leuA-22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (550 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (299 aa)
ilvEBranched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (329 aa)
AEA62960.1Branched-chain amino acid aminotransferase. (366 aa)
argC-2N-acetyl-gamma-glutamyl-phosphate reductase, subtype; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. (309 aa)
AEA63583.1Hypothetical protein; Belongs to the TPP enzyme family. (557 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (212 aa)
leuC3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (468 aa)
AEA64255.1Aspartate-semialdehyde dehydrogenase; Belongs to the aspartate-semialdehyde dehydrogenase family. (363 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (355 aa)
leuD-2Isopropylmalate isomerase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (216 aa)
leuC-2Isopropylmalate isomerase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
AEA64263.1Citrate synthase I; Belongs to the citrate synthase family. (434 aa)
AEA64274.1Aconitase A; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (905 aa)
AEA64657.1Hypothetical protein; Belongs to the TPP enzyme family. (546 aa)
AEA64839.1Aconitate hydratase domain-containing protein. (872 aa)
AEA64860.1Acetylornithine deacetylase. (389 aa)
AEA64900.1Putative transcriptional regulator, GntR family protein. (408 aa)
AEA64950.1Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (590 aa)
Your Current Organism:
Burkholderia gladioli
NCBI taxonomy Id: 999541
Other names: B. gladioli BSR3, Burkholderia gladioli BSR3, Burkholderia gladioli str. BSR3, Burkholderia gladioli strain BSR3
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