(33 nodes) Nervous system development network (Botrytis cinerea T4)

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Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	G2YV41_BOTF4	Similar to actin-depolymerizing factor 1; Belongs to the actin-binding proteins ADF family. (138 aa)
	G2YVS2_BOTF4	Similar to allantoinase. (539 aa)
	G2XND8_BOTF4	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1681 aa)
	G2YRP8_BOTF4	Similar to AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family. (437 aa)
	G2YV40_BOTF4	ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (91 aa)
	G2YK00_BOTF4	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (234 aa)
	G2YKA0_BOTF4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (733 aa)
	G2YNV9_BOTF4	Ricin B-type lectin domain-containing protein. (153 aa)
	G2YI85_BOTF4	Similar to polyubiquitin protein. (305 aa)
	G2YHW0_BOTF4	BcMKK1, mitogen-activated protein kinase; Belongs to the protein kinase superfamily. (494 aa)
	G2YEH0_BOTF4	BOS5, mitogen-activated protein kinase kinase. (641 aa)
	G2YD64_BOTF4	BcPG3, endopolygalacturonase 3. (514 aa)
	G2YCA3_BOTF4	PH domain-containing protein. (445 aa)
	SLX4	Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (934 aa)
	G2Y5H8_BOTF4	Uncharacterized protein. (656 aa)
	G2Y348_BOTF4	Uncharacterized protein. (429 aa)
	G2Y347_BOTF4	Uncharacterized protein. (1168 aa)
	G2Y346_BOTF4	Uncharacterized protein. (156 aa)
	G2Y1I4_BOTF4	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (1004 aa)
	G2Y069_BOTF4	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (161 aa)
	G2XZW5_BOTF4	HET domain-containing protein. (281 aa)
	G2XZC9_BOTF4	Jacalin-type lectin domain-containing protein. (367 aa)
	G2XXY7_BOTF4	Ubiquitin-like domain-containing protein. (323 aa)
	G2XXL3_BOTF4	Similar to MAP kinase kinase Ste7. (520 aa)
	G2YYF7_BOTF4	Similar to isoaspartyl dipeptidase. (489 aa)
	G2YY48_BOTF4	BcRAC, Rac-like GTPase. (199 aa)
	G2YVT7_BOTF4	BcPG6, endopolygalacturonase 6. (370 aa)
	G2XWD2_BOTF4	Similar to transcription factor Homeo. (322 aa)
	G2XWD1_BOTF4	Uncharacterized protein. (101 aa)
	G2XUA8_BOTF4	Similar to transcription factor Cys6. (896 aa)
	G2XS80_BOTF4	Protein related to plant expansins. (137 aa)
	G2XRG1_BOTF4	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration. (742 aa)
	G2XRF8_BOTF4	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (355 aa)

Your Current Organism:

Botrytis cinerea T4

NCBI taxonomy Id: 999810
Other names: B. cinerea T4, Botryotinia fuckeliana T4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
G2XND8_BOTF4	G2XRF8_BOTF4	G2XND8	G2XRF8	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.641
G2XND8_BOTF4	G2XRG1_BOTF4	G2XND8	G2XRG1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.955
G2XND8_BOTF4	G2XUA8_BOTF4	G2XND8	G2XUA8	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Similar to transcription factor Cys6.	0.602
G2XND8_BOTF4	G2XXY7_BOTF4	G2XND8	G2XXY7	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Ubiquitin-like domain-containing protein.	0.955
G2XND8_BOTF4	G2Y069_BOTF4	G2XND8	G2Y069	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.925
G2XND8_BOTF4	G2Y1I4_BOTF4	G2XND8	G2Y1I4	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.901
G2XND8_BOTF4	G2Y346_BOTF4	G2XND8	G2Y346	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.678
G2XND8_BOTF4	G2Y347_BOTF4	G2XND8	G2Y347	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.678
G2XND8_BOTF4	G2Y348_BOTF4	G2XND8	G2Y348	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.678
G2XND8_BOTF4	G2Y5H8_BOTF4	G2XND8	G2Y5H8	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Uncharacterized protein.	0.864
G2XND8_BOTF4	G2YCA3_BOTF4	G2XND8	G2YCA3	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	PH domain-containing protein.	0.627
G2XND8_BOTF4	G2YD64_BOTF4	G2XND8	G2YD64	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	BcPG3, endopolygalacturonase 3.	0.678
G2XND8_BOTF4	G2YI85_BOTF4	G2XND8	G2YI85	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Similar to polyubiquitin protein.	0.717
G2XND8_BOTF4	G2YK00_BOTF4	G2XND8	G2YK00	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.999
G2XND8_BOTF4	G2YKA0_BOTF4	G2XND8	G2YKA0	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.955
G2XND8_BOTF4	G2YRP8_BOTF4	G2XND8	G2YRP8	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	Similar to AP-2 complex subunit mu-1; Belongs to the adaptor complexes medium subunit family.	0.941
G2XND8_BOTF4	G2YVT7_BOTF4	G2XND8	G2YVT7	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	BcPG6, endopolygalacturonase 6.	0.678
G2XND8_BOTF4	G2YY48_BOTF4	G2XND8	G2YY48	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	BcRAC, Rac-like GTPase.	0.788
G2XRF8_BOTF4	G2XND8_BOTF4	G2XRF8	G2XND8	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.641
G2XRF8_BOTF4	G2XRG1_BOTF4	G2XRF8	G2XRG1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	AP complex subunit beta; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration.	0.526