(31 nodes) Skeletal muscle fiber development network (Urocitellus parryii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ACTA1	Actin alpha 1, skeletal muscle. (377 aa)
	SMO	Smoothened, frizzled class receptor. (788 aa)
	RCAN1	Regulator of calcineurin 1. (249 aa)
	SKI	SKI proto-oncogene. (728 aa)
	DNER	Delta/notch like EGF repeat containing. (749 aa)
	RIPOR2	RHO family interacting cell polarization regulator 2. (1077 aa)
	MYORG	Myogenesis regulating glycosidase (putative). (714 aa)
	MYOD1	Myogenic differentiation 1. (318 aa)
	CAV2	Caveolin 2. (162 aa)
	MYOG	Myogenin. (249 aa)
	SIX1	SIX homeobox 1. (284 aa)
	WNT10B	Wnt family member 10B. (389 aa)
	KLHL41	Kelch like family member 41. (606 aa)
	CNTNAP1	Contactin associated protein 1. (1381 aa)
	KEL	Kell metallo-endopeptidase (Kell blood group). (713 aa)
	SPG11	SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
	CACNA1S	Calcium voltage-gated channel subunit alpha1 S. (1875 aa)
	RYR1	Ryanodine receptor 1. (5060 aa)
	PPP3CB	Protein phosphatase 3 catalytic subunit beta. (552 aa)
	KLHL40	Kelch like family member 40. (623 aa)
	PPP3CA	Protein phosphatase 3 catalytic subunit alpha. (521 aa)
	HOMER1	Homer scaffold protein 1. (354 aa)
	R3HDM2	R3H domain containing 2. (1042 aa)
	XK	X-linked Kx blood group. (443 aa)
	BIN3	Bridging integrator 3. (287 aa)
	ENSUPAP00010027520	annotation not available (555 aa)
	LMOD3	Leiomodin 3. (562 aa)
	GPX1	Glutathione peroxidase 1. (201 aa)
	PMP22	Peripheral myelin protein 22. (160 aa)
	P2RX2	Purinergic receptor P2X 2. (413 aa)
	NFATC3	Nuclear factor of activated T cells 3. (1161 aa)

Your Current Organism:

Urocitellus parryii

NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTA1	CAV2	ENSUPAP00010000340	ENSUPAP00010009554	Actin alpha 1, skeletal muscle.	Caveolin 2.	0.518
ACTA1	LMOD3	ENSUPAP00010000340	ENSUPAP00010027746	Actin alpha 1, skeletal muscle.	Leiomodin 3.	0.595
CACNA1S	CAV2	ENSUPAP00010012488	ENSUPAP00010009554	Calcium voltage-gated channel subunit alpha1 S.	Caveolin 2.	0.688
CACNA1S	PPP3CA	ENSUPAP00010012488	ENSUPAP00010015770	Calcium voltage-gated channel subunit alpha1 S.	Protein phosphatase 3 catalytic subunit alpha.	0.647
CACNA1S	PPP3CB	ENSUPAP00010012488	ENSUPAP00010013529	Calcium voltage-gated channel subunit alpha1 S.	Protein phosphatase 3 catalytic subunit beta.	0.647
CACNA1S	R3HDM2	ENSUPAP00010012488	ENSUPAP00010021479	Calcium voltage-gated channel subunit alpha1 S.	R3H domain containing 2.	0.821
CACNA1S	RYR1	ENSUPAP00010012488	ENSUPAP00010013069	Calcium voltage-gated channel subunit alpha1 S.	Ryanodine receptor 1.	0.970
CAV2	ACTA1	ENSUPAP00010009554	ENSUPAP00010000340	Caveolin 2.	Actin alpha 1, skeletal muscle.	0.518
CAV2	CACNA1S	ENSUPAP00010009554	ENSUPAP00010012488	Caveolin 2.	Calcium voltage-gated channel subunit alpha1 S.	0.688
ENSUPAP00010027520	RYR1	ENSUPAP00010027520	ENSUPAP00010013069	annotation not available	Ryanodine receptor 1.	0.541
HOMER1	PPP3CA	ENSUPAP00010016824	ENSUPAP00010015770	Homer scaffold protein 1.	Protein phosphatase 3 catalytic subunit alpha.	0.419
HOMER1	PPP3CB	ENSUPAP00010016824	ENSUPAP00010013529	Homer scaffold protein 1.	Protein phosphatase 3 catalytic subunit beta.	0.415
HOMER1	RYR1	ENSUPAP00010016824	ENSUPAP00010013069	Homer scaffold protein 1.	Ryanodine receptor 1.	0.411
KEL	XK	ENSUPAP00010012299	ENSUPAP00010021914	Kell metallo-endopeptidase (Kell blood group).	X-linked Kx blood group.	0.863
KLHL40	KLHL41	ENSUPAP00010015161	ENSUPAP00010011837	Kelch like family member 40.	Kelch like family member 41.	0.898
KLHL40	LMOD3	ENSUPAP00010015161	ENSUPAP00010027746	Kelch like family member 40.	Leiomodin 3.	0.642
KLHL40	SMO	ENSUPAP00010015161	ENSUPAP00010001940	Kelch like family member 40.	Smoothened, frizzled class receptor.	0.613
KLHL41	KLHL40	ENSUPAP00010011837	ENSUPAP00010015161	Kelch like family member 41.	Kelch like family member 40.	0.898
KLHL41	LMOD3	ENSUPAP00010011837	ENSUPAP00010027746	Kelch like family member 41.	Leiomodin 3.	0.677
KLHL41	SMO	ENSUPAP00010011837	ENSUPAP00010001940	Kelch like family member 41.	Smoothened, frizzled class receptor.	0.613