(17 nodes) Regulation of store-operated calcium entry network (Urocitellus parryii)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NFATC3	Nuclear factor of activated T cells 3. (1161 aa)
	CRACR2B	Calcium release activated channel regulator 2B. (400 aa)
	STC2	Stanniocalcin 2. (296 aa)
	SARAF	Store-operated calcium entry associated regulatory factor. (320 aa)
	STIM1	Stromal interaction molecule 1. (817 aa)
	CD84	CD84 molecule. (355 aa)
	SPINK1	Serine peptidase inhibitor, Kazal type 1. (77 aa)
	SPG11	SPG11 vesicle trafficking associated, spatacsin. (2443 aa)
	TRPC4	Transient receptor potential cation channel subfamily C member 4. (977 aa)
	SLC8B1	Solute carrier family 8 member B1. (581 aa)
	GRAMD2A	GRAM domain containing 2A. (311 aa)
	HOMER1	Homer scaffold protein 1. (354 aa)
	ENSUPAP00010022996	annotation not available (359 aa)
	HOMER2	Homer scaffold protein 2. (371 aa)
	EFHB	EF-hand domain family member B. (670 aa)
	CASQ1	Calsequestrin 1. (404 aa)
	JPH4	Junctophilin 4. (628 aa)

Your Current Organism:

Urocitellus parryii

NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASQ1	JPH4	ENSUPAP00010013897	ENSUPAP00010013005	Calsequestrin 1.	Junctophilin 4.	0.664
CRACR2B	STIM1	ENSUPAP00010028990	ENSUPAP00010024279	Calcium release activated channel regulator 2B.	Stromal interaction molecule 1.	0.539
EFHB	SARAF	ENSUPAP00010021055	ENSUPAP00010026048	EF-hand domain family member B.	Store-operated calcium entry associated regulatory factor.	0.543
ENSUPAP00010022996	HOMER1	ENSUPAP00010022996	ENSUPAP00010016824	annotation not available	Homer scaffold protein 1.	0.981
ENSUPAP00010022996	HOMER2	ENSUPAP00010022996	ENSUPAP00010017904	annotation not available	Homer scaffold protein 2.	0.962
HOMER1	ENSUPAP00010022996	ENSUPAP00010016824	ENSUPAP00010022996	Homer scaffold protein 1.	annotation not available	0.981
HOMER1	HOMER2	ENSUPAP00010016824	ENSUPAP00010017904	Homer scaffold protein 1.	Homer scaffold protein 2.	0.974
HOMER1	STIM1	ENSUPAP00010016824	ENSUPAP00010024279	Homer scaffold protein 1.	Stromal interaction molecule 1.	0.408
HOMER2	ENSUPAP00010022996	ENSUPAP00010017904	ENSUPAP00010022996	Homer scaffold protein 2.	annotation not available	0.962
HOMER2	HOMER1	ENSUPAP00010017904	ENSUPAP00010016824	Homer scaffold protein 2.	Homer scaffold protein 1.	0.974
JPH4	CASQ1	ENSUPAP00010013005	ENSUPAP00010013897	Junctophilin 4.	Calsequestrin 1.	0.664
SARAF	EFHB	ENSUPAP00010026048	ENSUPAP00010021055	Store-operated calcium entry associated regulatory factor.	EF-hand domain family member B.	0.543
SARAF	STIM1	ENSUPAP00010026048	ENSUPAP00010024279	Store-operated calcium entry associated regulatory factor.	Stromal interaction molecule 1.	0.705
STIM1	CRACR2B	ENSUPAP00010024279	ENSUPAP00010028990	Stromal interaction molecule 1.	Calcium release activated channel regulator 2B.	0.539
STIM1	HOMER1	ENSUPAP00010024279	ENSUPAP00010016824	Stromal interaction molecule 1.	Homer scaffold protein 1.	0.408
STIM1	SARAF	ENSUPAP00010024279	ENSUPAP00010026048	Stromal interaction molecule 1.	Store-operated calcium entry associated regulatory factor.	0.705
STIM1	TRPC4	ENSUPAP00010024279	ENSUPAP00010011720	Stromal interaction molecule 1.	Transient receptor potential cation channel subfamily C member 4.	0.825
TRPC4	STIM1	ENSUPAP00010011720	ENSUPAP00010024279	Transient receptor potential cation channel subfamily C member 4.	Stromal interaction molecule 1.	0.825