STRINGSTRING
RASGRP3 RASGRP3 RAC3 RAC3 NFATC2 NFATC2 NFKBIA NFKBIA Cd79b Cd79b ENSUPAP00010001529 ENSUPAP00010001529 IGHM IGHM ENSUPAP00010002510 ENSUPAP00010002510 LYN LYN ERAS ERAS NFATC1 NFATC1 VAV3 VAV3 SOS1 SOS1 NFKBIE NFKBIE ENSUPAP00010005521 ENSUPAP00010005521 RAC2 RAC2 ENSUPAP00010005811 ENSUPAP00010005811 ENSUPAP00010007589 ENSUPAP00010007589 RAC1 RAC1 ENSUPAP00010008974 ENSUPAP00010008974 ENSUPAP00010009568 ENSUPAP00010009568 PIK3CB PIK3CB ENSUPAP00010009681 ENSUPAP00010009681 SOS2 SOS2 PLCG2 PLCG2 VAV2 VAV2 ENSUPAP00010011264 ENSUPAP00010011264 ENSUPAP00010011329 ENSUPAP00010011329 ENSUPAP00010011624 ENSUPAP00010011624 RELA RELA NFKBIB NFKBIB MAPK3 MAPK3 BTK BTK INPP5D INPP5D ENSUPAP00010013159 ENSUPAP00010013159 IKBKG IKBKG PPP3CB PPP3CB CD22 CD22 CD19 CD19 BCL10 BCL10 PTPN6 PTPN6 MALT1 MALT1 NFKB1 NFKB1 PPP3CA PPP3CA DAPP1 DAPP1 MAPK1 MAPK1 CARD11 CARD11 FOS FOS BLNK BLNK PIK3AP1 PIK3AP1 KRAS KRAS ENSUPAP00010020469 ENSUPAP00010020469 PPP3CC PPP3CC CD72 CD72 MAP2K1 MAP2K1 AKT3 AKT3 CHUK CHUK AKT1 AKT1 ENSUPAP00010023672 ENSUPAP00010023672 ENSUPAP00010023723 ENSUPAP00010023723 ENSUPAP00010023777 ENSUPAP00010023777 ENSUPAP00010023785 ENSUPAP00010023785 VAV1 VAV1 ENSUPAP00010024792 ENSUPAP00010024792 INPPL1 INPPL1 GSK3B GSK3B ENSUPAP00010025995 ENSUPAP00010025995 ENSUPAP00010026094 ENSUPAP00010026094 ENSUPAP00010026110 ENSUPAP00010026110 ENSUPAP00010026125 ENSUPAP00010026125 JUN JUN PIK3R1 PIK3R1 CD81 CD81 CD79A CD79A NRAS NRAS CSDE1 CSDE1 AKT2 AKT2 IKBKB IKBKB PIK3CA PIK3CA HRAS HRAS NFATC3 NFATC3 GRB2 GRB2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RASGRP3RAS guanyl releasing protein 3. (636 aa)
RAC3Rac family small GTPase 3. (192 aa)
NFATC2Nuclear factor of activated T cells 2. (917 aa)
NFKBIANFKB inhibitor alpha. (314 aa)
Cd79bCD79b molecule. (230 aa)
ENSUPAP00010001529annotation not available (226 aa)
IGHMImmunoglobulin heavy constant mu. (448 aa)
ENSUPAP00010002510annotation not available (1046 aa)
LYNLYN proto-oncogene, Src family tyrosine kinase. (512 aa)
ERASES cell expressed Ras. (227 aa)
NFATC1Nuclear factor of activated T cells 1. (904 aa)
VAV3Vav guanine nucleotide exchange factor 3. (501 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
NFKBIENFKB inhibitor epsilon. (362 aa)
ENSUPAP00010005521annotation not available (177 aa)
RAC2Rac family small GTPase 2. (192 aa)
ENSUPAP00010005811annotation not available (127 aa)
ENSUPAP00010007589annotation not available (113 aa)
RAC1Rac family small GTPase 1. (212 aa)
ENSUPAP00010008974annotation not available (186 aa)
ENSUPAP00010009568annotation not available (506 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta. (1070 aa)
ENSUPAP00010009681annotation not available (142 aa)
SOS2SOS Ras/Rho guanine nucleotide exchange factor 2. (1327 aa)
PLCG2Phospholipase C gamma 2. (1266 aa)
VAV2Vav guanine nucleotide exchange factor 2. (862 aa)
ENSUPAP00010011264annotation not available (287 aa)
ENSUPAP00010011329annotation not available (169 aa)
ENSUPAP00010011624annotation not available (400 aa)
RELARELA proto-oncogene, NF-kB subunit. (554 aa)
NFKBIBNFKB inhibitor beta. (360 aa)
MAPK3Mitogen-activated protein kinase 3. (265 aa)
BTKBruton tyrosine kinase. (659 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1197 aa)
ENSUPAP00010013159annotation not available (170 aa)
IKBKGInhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (428 aa)
PPP3CBProtein phosphatase 3 catalytic subunit beta. (552 aa)
CD22CD22 molecule. (888 aa)
CD19CD19 molecule. (543 aa)
BCL10BCL10 immune signaling adaptor. (232 aa)
PTPN6Protein tyrosine phosphatase non-receptor type 6. (597 aa)
MALT1MALT1 paracaspase. (834 aa)
NFKB1Nuclear factor kappa B subunit 1. (972 aa)
PPP3CAProtein phosphatase 3 catalytic subunit alpha. (521 aa)
DAPP1Dual adaptor of phosphotyrosine and 3-phosphoinositides 1. (280 aa)
MAPK1Mitogen-activated protein kinase 1. (360 aa)
CARD11Caspase recruitment domain family member 11. (1152 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
BLNKB cell linker. (457 aa)
PIK3AP1Phosphoinositide-3-kinase adaptor protein 1. (806 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
ENSUPAP00010020469annotation not available (1408 aa)
PPP3CCProtein phosphatase 3 catalytic subunit gamma. (509 aa)
CD72CD72 molecule. (363 aa)
MAP2K1Mitogen-activated protein kinase kinase 1. (393 aa)
AKT3AKT serine/threonine kinase 3. (479 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (744 aa)
AKT1AKT serine/threonine kinase 1. (480 aa)
ENSUPAP00010023672annotation not available (445 aa)
ENSUPAP00010023723annotation not available (724 aa)
ENSUPAP00010023777annotation not available (175 aa)
ENSUPAP00010023785annotation not available (84 aa)
VAV1Vav guanine nucleotide exchange factor 1. (845 aa)
ENSUPAP00010024792annotation not available (341 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
GSK3BGlycogen synthase kinase 3 beta. (433 aa)
ENSUPAP00010025995annotation not available (461 aa)
ENSUPAP00010026094annotation not available (126 aa)
ENSUPAP00010026110annotation not available (155 aa)
ENSUPAP00010026125annotation not available (173 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit. (335 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CD81CD81 molecule. (236 aa)
CD79ACD79a molecule. (222 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
CSDE1Cold shock domain containing E1. (843 aa)
AKT2AKT serine/threonine kinase 2. (501 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
PIK3CAPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha. (1068 aa)
HRASHRas proto-oncogene, GTPase. (197 aa)
NFATC3Nuclear factor of activated T cells 3. (1161 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
Your Current Organism:
Urocitellus parryii
NCBI taxonomy Id: 9999
Other names: Arctic ground squirrel, Citellus parryii, Spermophilus parryi, Spermophilus parryii, U. parryii
Server load: low (34%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.