STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
V6HXA2_9LEPTUnannotated protein. (305 aa)    
Predicted Functional Partners:
V6IB99_9LEPT
Unannotated protein.
  
 0.993
dnaK
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.940
grpE
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depe [...]
  
 
 0.871
V6IFY0_9LEPT
Unannotated protein.
  
 0.856
V6HZS4_9LEPT
Unannotated protein.
  
 0.856
V6HYM6_9LEPT
Unannotated protein.
       0.838
rplQ
Unannotated protein.
  
   0.783
rplM
Unannotated protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.774
rplK
Unannotated protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.771
V6IB73_9LEPT
Unannotated protein.
   
 0.769
Your Current Organism:
Leptospira alexanderi
NCBI taxonomy Id: 100053
Other names: ATCC 700520, L. alexanderi, Leptospira genomosp. 2, Leptospira genomospecies 2, Leptospira genospecies 2, strain L 60
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.