STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for nuclear migration during vegetative growth as well as development. Required for retrograde early endosome (EE) transport from the hyphal tip. Required for localization of dynein to the mitotic spindle poles. Recruits additional proteins to the dynein complex at SPBs; Belongs to the WD repeat LIS1/nudF family. (464 aa)    
Predicted Functional Partners:
A0A1Y2XDN1
Uncharacterized protein.
    
 0.996
A0A1Y2WVR2
NUDE_C domain-containing protein.
    
 
 0.949
A0A1Y2X8R7
CS domain-containing protein.
   
 0.946
A0A1Y2WMV6
Uncharacterized protein.
   
 0.945
A0A1Y2WNN2
CAP-Gly domain-containing protein.
    
 0.933
K445DRAFT_9441
Uncharacterized protein.
    
 0.927
A0A1Y2X993
Uncharacterized protein.
    
 0.923
A0A1Y2X703
Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures.
    
 0.911
A0A1Y2WMA0
Uncharacterized protein.
    
 0.855
A0A1Y2X1N5
Uncharacterized protein.
   
 0.849
Your Current Organism:
Daldinia sp. EC12
NCBI taxonomy Id: 1001832
Other names: D. sp. EC12
Server load: low (16%) [HD]