A0A1Y2WVY5 protein (Daldinia sp. EC12) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

A0A1Y2WVY5

Uncharacterized protein. (340 aa)

Predicted Functional Partners:

A0A1Y2XDK5

0.990

A0A1Y2WWE6

0.922

A0A1Y2XCD3

0.922

A0A1Y2WSM7

0.894

A0A1Y2WVF8

0.894

A0A1Y2X105

0.894

A0A1Y2X5B6

0.894

A0A1Y2X7A1

0.894

A0A1Y2X133

0.861

A0A1Y2XBS1

0.796

Your Current Organism:

Daldinia sp. EC12

NCBI taxonomy Id: 1001832
Other names: D. sp. EC12

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structured XML interaction data, according to the 'PSI-MI' data standard

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A1Y2WSM7	A0A1Y2WVY5	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WSM7	A0A1Y2WWE6	Uncharacterized protein.	FK506-binding protein.	0.609
A0A1Y2WSM7	A0A1Y2X105	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.930
A0A1Y2WSM7	A0A1Y2X5B6	Uncharacterized protein.	Uncharacterized protein.	0.907
A0A1Y2WSM7	A0A1Y2XBS1	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.701
A0A1Y2WSM7	A0A1Y2XCD3	Uncharacterized protein.	Peptidylprolyl isomerase.	0.530
A0A1Y2WSM7	A0A1Y2XDK5	Uncharacterized protein.	Peptidylprolyl isomerase.	0.900
A0A1Y2WVF8	A0A1Y2WVY5	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WVF8	A0A1Y2WWE6	Uncharacterized protein.	FK506-binding protein.	0.607
A0A1Y2WVF8	A0A1Y2XBS1	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.652
A0A1Y2WVF8	A0A1Y2XCD3	Uncharacterized protein.	Peptidylprolyl isomerase.	0.530
A0A1Y2WVF8	A0A1Y2XDK5	Uncharacterized protein.	Peptidylprolyl isomerase.	0.822
A0A1Y2WVY5	A0A1Y2WSM7	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WVY5	A0A1Y2WVF8	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WVY5	A0A1Y2WWE6	Uncharacterized protein.	FK506-binding protein.	0.922
A0A1Y2WVY5	A0A1Y2X105	Uncharacterized protein.	Uncharacterized protein; Belongs to the calmodulin family.	0.894
A0A1Y2WVY5	A0A1Y2X133	Uncharacterized protein.	Carn_acyltransf domain-containing protein; Belongs to the carnitine/choline acetyltransferase family.	0.861
A0A1Y2WVY5	A0A1Y2X5B6	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WVY5	A0A1Y2X7A1	Uncharacterized protein.	Uncharacterized protein.	0.894
A0A1Y2WVY5	A0A1Y2XBS1	Uncharacterized protein.	Serine/threonine-protein phosphatase.	0.796

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.913

expected number of edges:

26

PPI enrichment p-value:

0.464

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 272

1.7

4.24

8.45e-16

GO:0032543

Mitochondrial translation

5 of 43

2.16

3.53

4.14e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

11 of 152

1.95

6.09

7.34e-19

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005761

Mitochondrial ribosome

11 of 61

2.35

9.44

3.08e-23

GO:0005762

Mitochondrial large ribosomal subunit

9 of 33

2.53

8.95

1.05e-19

GO:0044391

Ribosomal subunit

11 of 140

1.99

6.52

5.46e-20

GO:0098798

Mitochondrial protein-containing complex

11 of 173

1.9

5.86

2.20e-19

GO:0005763

Mitochondrial small ribosomal subunit

2 of 24

2.01

1.14

0.0064

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:6472

Organellar ribosome

11 of 64

2.33

9.15

1.14e-22

CL:6476

Organellar ribosome

6 of 22

2.53

5.66

5.68e-12

CL:6546

Organellar large ribosomal subunit, and Ribosomal protein S9

5 of 21

2.47

4.46

1.69e-09

CL:6504

Mixed, incl. Ribosomal protein L25/L23, and Ribosomal protein L30p/L7e

2 of 5

2.7

1.48

0.0020

CL:6549

Mixed, incl. Ribosomal protein S9, and Ribosomal protein L25/L23

2 of 6

2.62

1.43

0.0024

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

7 of 177

1.69

3.02

3.43e-09

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-72766

Translation

11 of 259

1.72

4.45

1.38e-16

MAP-392499

Metabolism of proteins

11 of 969

1.15

1.67

1.15e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005762

Mitochondrial large ribosomal subunit

9 of 32

2.54

9.03

8.28e-20

GOCC:0005761

Mitochondrial ribosome

11 of 69

2.3

8.96

1.34e-22

GOCC:0044391

Ribosomal subunit

11 of 146

1.97

6.38

7.99e-20

GOCC:0098798

Mitochondrial protein complex

11 of 160

1.93

6.12

1.05e-19

GOCC:0005763

Mitochondrial small ribosomal subunit

2 of 36

1.84

0.92

0.0165

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 106

1.85

3.12

2.79e-08

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