STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2WXS5HTH CENPB-type domain-containing protein. (325 aa)    
Predicted Functional Partners:
A0A1Y2X475
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.938
A0A1Y2XFX9
ThiF domain-containing protein.
    
 0.644
A0A1Y2WV32
Ubiquitin-activating enzyme E1-like; Belongs to the ubiquitin-activating E1 family.
    
  0.548
A0A1Y2X3I1
RWD domain-containing protein.
      
 0.476
A0A1Y2WYS9
Histone H3; Belongs to the histone H3 family.
    
 
 0.460
A0A1Y2X888
Histone domain-containing protein.
    
 
 0.460
A0A1Y2XC60
Uncharacterized protein.
    
  0.450
A0A1Y2WRK6
Uncharacterized protein.
    
  0.444
A0A1Y2X477
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
      
 0.444
A0A1Y2XDU3
Uncharacterized protein.
    
  0.444
Your Current Organism:
Daldinia sp. EC12
NCBI taxonomy Id: 1001832
Other names: D. sp. EC12
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.