STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2X8N6WD_REPEATS_REGION domain-containing protein. (1412 aa)    
Predicted Functional Partners:
A0A1Y2WQX1
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.823
A0A1Y2WXM2
IU_nuc_hydro domain-containing protein.
  
 
  0.805
A0A1Y2WTS3
Uncharacterized protein.
   
 
  0.775
A0A1Y2X427
DHO_dh domain-containing protein.
   
 
  0.775
A0A1Y2XFT9
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
  
 
 0.739
A0A1Y2X2D2
PfkB domain-containing protein.
  
 
 0.737
A0A1Y2XDB0
RibD_C domain-containing protein.
  
 
 0.737
A0A1Y2XFG9
PfkB domain-containing protein.
  
 
 0.737
A0A1Y2XBC7
CMP/dCMP-type deaminase domain-containing protein.
  
 
  0.645
A0A1Y2WSF6
tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance.
 
      0.598
Your Current Organism:
Daldinia sp. EC12
NCBI taxonomy Id: 1001832
Other names: D. sp. EC12
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