node1 | node2 | node1 annotation | node2 annotation | score |
A0A1Y2WQX1 | A0A1Y2WTS3 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Uncharacterized protein. | 0.859 |
A0A1Y2WQX1 | A0A1Y2WXM2 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | IU_nuc_hydro domain-containing protein. | 0.763 |
A0A1Y2WQX1 | A0A1Y2X2D2 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | PfkB domain-containing protein. | 0.736 |
A0A1Y2WQX1 | A0A1Y2X427 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | DHO_dh domain-containing protein. | 0.859 |
A0A1Y2WQX1 | A0A1Y2X8N6 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | WD_REPEATS_REGION domain-containing protein. | 0.823 |
A0A1Y2WQX1 | A0A1Y2XBC7 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | CMP/dCMP-type deaminase domain-containing protein. | 0.845 |
A0A1Y2WQX1 | A0A1Y2XDB0 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | RibD_C domain-containing protein. | 0.736 |
A0A1Y2WQX1 | A0A1Y2XFG9 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | PfkB domain-containing protein. | 0.802 |
A0A1Y2WQX1 | A0A1Y2XFT9 | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.736 |
A0A1Y2WSF6 | A0A1Y2X8N6 | tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. | WD_REPEATS_REGION domain-containing protein. | 0.598 |
A0A1Y2WTS3 | A0A1Y2WQX1 | Uncharacterized protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.859 |
A0A1Y2WTS3 | A0A1Y2WXM2 | Uncharacterized protein. | IU_nuc_hydro domain-containing protein. | 0.545 |
A0A1Y2WTS3 | A0A1Y2X427 | Uncharacterized protein. | DHO_dh domain-containing protein. | 0.791 |
A0A1Y2WTS3 | A0A1Y2X8N6 | Uncharacterized protein. | WD_REPEATS_REGION domain-containing protein. | 0.775 |
A0A1Y2WTS3 | A0A1Y2XBC7 | Uncharacterized protein. | CMP/dCMP-type deaminase domain-containing protein. | 0.662 |
A0A1Y2WXM2 | A0A1Y2WQX1 | IU_nuc_hydro domain-containing protein. | S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. | 0.763 |
A0A1Y2WXM2 | A0A1Y2WTS3 | IU_nuc_hydro domain-containing protein. | Uncharacterized protein. | 0.545 |
A0A1Y2WXM2 | A0A1Y2X2D2 | IU_nuc_hydro domain-containing protein. | PfkB domain-containing protein. | 0.503 |
A0A1Y2WXM2 | A0A1Y2X427 | IU_nuc_hydro domain-containing protein. | DHO_dh domain-containing protein. | 0.544 |
A0A1Y2WXM2 | A0A1Y2X8N6 | IU_nuc_hydro domain-containing protein. | WD_REPEATS_REGION domain-containing protein. | 0.805 |