STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A1Y2XFL3Uncharacterized protein. (558 aa)    
Predicted Functional Partners:
A0A1Y2X2U3
Phos_pyr_kin domain-containing protein.
   
 
 0.737
A0A1Y2X477
Thiamine thiazole synthase; Involved in biosynthesis of the thiamine precursor thiazole. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5- (2-hydroxyethyl)-4-methylthiazole-2-carboxylic acid (ADT), an adenylated thiazole intermediate. The reaction includes an iron- dependent sulfide transfer from a conserved cysteine residue of the protein to a thiazole intermediate. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme. May have additional roles in adaptation to various stress conditions and in DNA damage tolerance; Belongs to the T [...]
  
  
 0.730
A0A1Y2WM91
Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family.
    
 0.724
A0A1Y2WK07
Uncharacterized protein.
    
 0.695
A0A1Y2X0N5
Uncharacterized protein.
     
 0.668
A0A1Y2WMS4
LMWPc domain-containing protein.
    
  0.619
A0A1Y2WUN6
Carbohydrate esterase family 3 protein.
  
 
  0.605
A0A1Y2X5Z3
Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.
  
 
  0.605
A0A1Y2WJI8
Uncharacterized protein.
   
 
 0.592
A0A1Y2XFH9
Uncharacterized protein.
   
 
 0.592
Your Current Organism:
Daldinia sp. EC12
NCBI taxonomy Id: 1001832
Other names: D. sp. EC12
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