STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ern1Serine/threonine-protein kinase/endoribonuclease IRE1. (406 aa)    
Predicted Functional Partners:
Hspa5
78 kDa glucose-regulated protein; Belongs to the heat shock protein 70 family.
   
 0.993
Traf2
TNF receptor-associated factor.
    
 0.981
Map3k5
Mitogen-activated protein kinase kinase kinase 5.
   
 0.972
Xbp1
LOW QUALITY PROTEIN: X-box-binding protein 1.
    
 0.937
Traf1
TNF receptor-associated factor.
    
 0.935
Ankrd45
Ankyrin repeat domain-containing protein 45 isoform X1.
   
 0.917
Psen1
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.887
Psen2
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.879
Map3k6
Mitogen-activated protein kinase kinase kinase 6.
   
 0.782
Syvn1
E3 ubiquitin-protein ligase synoviolin.
    
 
 0.758
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.