Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DldDihydrolipoyl dehydrogenase. (491 aa)    
Predicted Functional Partners:
Dlst
Dihydrolipoamide S-succinyltransferase.
 
 0.999
Amt
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 0.999
Ogdhl
2-oxoglutarate dehydrogenase-like, mitochondrial isoform X1.
  
 0.999
Bckdhb
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
  
 0.999
Pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
Pdha1
Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
   
 0.999
Ogdh
2-oxoglutarate dehydrogenase, mitochondrial isoform X1.
  
 0.999
Dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.999
Dlat
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
LOC105995863
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial-like.
   
 0.999
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (12%) [HD]