STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Klhl11Kelch-like protein 11. (708 aa)    
Predicted Functional Partners:
Cul3
Cullin-3 isoform X1; Belongs to the cullin family.
    
 0.980
Cul1
Cullin-1; Belongs to the cullin family.
    
 0.950
Cacul1
CDK2-associated and cullin domain-containing protein 1; Belongs to the cullin family.
    
 0.700
Ube2m
NEDD8-conjugating enzyme Ubc12; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.688
Kbtbd8
Kelch repeat and BTB domain-containing protein 8 isoform X1.
    
 
0.687
Rbx1
E3 ubiquitin-protein ligase RBX1.
    
 0.675
Nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
     
 0.672
Commd4
COMM domain-containing protein 4.
     
 0.661
Nedd8
NEDD8.
     
 0.660
Ube2f
NEDD8-conjugating enzyme UBE2F; Belongs to the ubiquitin-conjugating enzyme family.
    
  0.652
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.