STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hddc2HD domain-containing protein 2. (195 aa)    
Predicted Functional Partners:
Ephx2
Bifunctional epoxide hydrolase 2.
    
 0.870
Tk1
Thymidine kinase.
    
  0.865
Dtymk
Thymidylate kinase.
  
 
  0.863
Tyms
Thymidylate synthase.
    
 0.853
Tymp
Thymidine phosphorylase.
     
 0.851
Pnp
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 
  0.828
Mtap
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
  0.828
Nt5el
5'-nucleotidase-like; Belongs to the 5'-nucleotidase family.
    
 0.814
Nt5e
5'-nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.814
Nudt12
Peroxisomal NADH pyrophosphatase NUDT12.
    
  0.812
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.