STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ucp3Mitochondrial uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa)    
Predicted Functional Partners:
Ppargc1a
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha.
      
 0.537
Pparg
Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...]
   
 
 0.464
Cpt1b
Carnitine O-palmitoyltransferase 1, muscle isoform; Belongs to the carnitine/choline acetyltransferase family.
   
  
 0.449
Tm2d3
TM2 domain-containing protein 3.
      
 0.435
Nufip2
Nuclear fragile X mental retardation-interacting protein 2.
      
 0.434
Slc25a27
Mitochondrial uncoupling protein 4 isoform X2; Belongs to the mitochondrial carrier (TC 2.A.29) family.
     
0.430
Mfn1
Mitofusin-1 isoform X1; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family.
      
 0.430
Fis1
Mitochondrial fission 1 protein; Involved in the fragmentation of the mitochondrial network and its perinuclear clustering.
      
 0.429
Pink1
Serine/threonine-protein kinase PINK1, mitochondrial.
    
 
 0.419
Ppara
Peroxisome proliferator-activated receptor alpha isoform X1.
   
 
 0.408
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.