Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
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[Homology]
Score
Prdm5PR/SET domain 5. (415 aa)    
Predicted Functional Partners:
Kng1
Kininogen-1 isoform X3.
    
 
 0.822
Uros
uroporphyrinogen-III synthase.
    
 
 0.816
Fancm
Fanconi anemia group M protein.
    
  0.811
Sh3rf3
SH3 domain-containing RING finger protein 3 isoform X1.
    
 0.715
Svep1
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1.
    
 0.694
Hapln1
Hyaluronan and proteoglycan link protein 1.
    
 0.690
Pde6d
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 
 0.689
Nme8
Thioredoxin domain-containing protein 3 isoform X1.
    
 0.675
Btn1a1
Butyrophilin subfamily 1 member A1-like.
    
 0.669
Pcolce2
Procollagen C-endopeptidase enhancer 2.
      
 0.667
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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