STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pptc7Protein phosphatase; Belongs to the PP2C family. (305 aa)    
Predicted Functional Partners:
Tab3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3.
   
 0.655
Tab2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2.
   
 0.636
Traf7
E3 ubiquitin-protein ligase TRAF7 isoform X3.
    
 0.634
Bckdhb
2-oxoisovalerate dehydrogenase subunit beta, mitochondrial.
   
 0.634
LOC105981059
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial pseudogene.
   
 0.634
Pdhb
Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.634
Med31
Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
   0.614
Dlst
Dihydrolipoamide S-succinyltransferase.
   
 0.612
Pdhx
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.612
Dbt
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
   
 0.612
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.