STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hivep1Zinc finger protein 40. (2698 aa)    
Predicted Functional Partners:
Btrc
F-box/WD repeat-containing protein 1A.
    
  0.724
Arid4b
AT-rich interactive domain-containing protein 4B.
    
 0.695
Ankrd22
Ankyrin repeat domain-containing protein 22.
    
 
 0.621
Mrps33
28S ribosomal protein S33, mitochondrial.
    
 0.615
Lamtor2
Ragulator complex protein LAMTOR2.
    
  0.612
Blk
Tyrosine-protein kinase.
    
 0.611
Mrps11
28S ribosomal protein S11, mitochondrial; Belongs to the universal ribosomal protein uS11 family.
    
  0.610
Sufu
Suppressor of fused homolog; Negative regulator in the hedgehog signaling pathway. Down- regulates GLI1-mediated transactivation of target genes. Part of a corepressor complex that acts on DNA-bound GLI1. May also act by linking GLI1 to BTRC and thereby targeting GLI1 to degradation by the proteasome. Sequesters GLI1, GLI2 and GLI3 in the cytoplasm, this effect is overcome by binding of STK36 to both SUFU and a GLI protein. Negative regulator of beta-catenin signaling. Regulates the formation of either the repressor form (GLI3R) or the activator form (GLI3A) of the full-length form of [...]
    
 0.609
Nme8
Thioredoxin domain-containing protein 3 isoform X1.
    
 0.608
Mrps15
28S ribosomal protein S15, mitochondrial; Belongs to the universal ribosomal protein uS15 family.
   
  0.605
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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