STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Setd2Histone-lysine N-methyltransferase SETD2. (2320 aa)    
Predicted Functional Partners:
Ash1l
Histone-lysine N-methyltransferase ASH1L.
   
 
0.980
Polr2a
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.966
Polr2c
DNA-directed RNA polymerase II subunit RPB3.
    
 0.956
Polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.952
Kmt2e
Histone-lysine N-methyltransferase 2E.
   
0.931
Izumo4
Izumo sperm-egg fusion protein 4.
   
 0.927
Dot1l
Histone-lysine N-methyltransferase, H3 lysine-79 specific.
   
 0.927
Setd1a
SET domain containing 1A, histone lysine methyltransferase.
   
 0.926
Setd1b
Histone-lysine N-methyltransferase SETD1B.
   
0.926
Setd1a-2
Histone-lysine N-methyltransferase SETD1A isoform X1.
   
0.926
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.