STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Me1NADP-dependent malic enzyme. (556 aa)    
Predicted Functional Partners:
Fh1
Fumarate hydratase, mitochondrial.
  
 
 0.946
Pcx
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 0.939
Mdh2
Malate dehydrogenase.
  
 0.928
Pkm
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.927
Pklr
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.927
Cs
Citrate synthase; Belongs to the citrate synthase family.
  
 0.922
Mdh1
Malate dehydrogenase.
  
 0.917
Ldhc
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.895
Ldhb
L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.895
Ldhd
Probable D-lactate dehydrogenase, mitochondrial isoform X1.
  
 
 0.881
Your Current Organism:
Dipodomys ordii
NCBI taxonomy Id: 10020
Other names: D. ordii
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.