STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SEV97958.1CBS domain-containing protein. (142 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase (NADH) large subunit.
    
 0.876
guaA
GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP.
    
 0.861
SEW11898.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.860
SEW08628.1
Pyruvate-ferredoxin/flavodoxin oxidoreductase.
    
  0.855
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.768
SEV95513.1
2-oxoglutarate ferredoxin oxidoreductase subunit alpha.
    
  0.697
SEW36840.1
2-oxoisovalerate dehydrogenase E1 component.
  
  
  0.681
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
  0.619
SEV97938.1
Transcriptional regulator, TetR family.
       0.515
SEV97883.1
GMP synthase (glutamine-hydrolysing).
 
  
 0.510
Your Current Organism:
Austwickia chelonae
NCBI taxonomy Id: 100225
Other names: A. chelonae, ATCC 51576, CCUG 47447, DSM 44178, Dermatophilus chelonae, JCM 9706, NBRC 105200, strain W16
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