node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEW01805.1 | SEW02985.1 | SAMN05421595_0866 | SAMN05421595_0924 | Sporulation and spore germination. | Protein of unknown function. | 0.606 |
SEW01805.1 | SEW03505.1 | SAMN05421595_0866 | SAMN05421595_0949 | Sporulation and spore germination. | Hypothetical protein. | 0.451 |
SEW01805.1 | SEW30096.1 | SAMN05421595_0866 | SAMN05421595_1879 | Sporulation and spore germination. | Lysophospholipase L1. | 0.460 |
SEW02985.1 | SEW01805.1 | SAMN05421595_0924 | SAMN05421595_0866 | Protein of unknown function. | Sporulation and spore germination. | 0.606 |
SEW02985.1 | SEW03051.1 | SAMN05421595_0924 | SAMN05421595_0927 | Protein of unknown function. | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.658 |
SEW02985.1 | SEW03505.1 | SAMN05421595_0924 | SAMN05421595_0949 | Protein of unknown function. | Hypothetical protein. | 0.693 |
SEW02985.1 | SEW30096.1 | SAMN05421595_0924 | SAMN05421595_1879 | Protein of unknown function. | Lysophospholipase L1. | 0.699 |
SEW02985.1 | clpS | SAMN05421595_0924 | SAMN05421595_0923 | Protein of unknown function. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.907 |
SEW02985.1 | murI | SAMN05421595_0924 | SAMN05421595_0925 | Protein of unknown function. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.737 |
SEW02985.1 | pncA | SAMN05421595_0924 | SAMN05421595_0921 | Protein of unknown function. | Nicotinamidase/pyrazinamidase. | 0.663 |
SEW02985.1 | pncB | SAMN05421595_0924 | SAMN05421595_0922 | Protein of unknown function. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.708 |
SEW02985.1 | rph | SAMN05421595_0924 | SAMN05421595_0926 | Protein of unknown function. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.658 |
SEW02985.1 | senX3 | SAMN05421595_0924 | SAMN05421595_0336 | Protein of unknown function. | Two-component system, OmpR family, sensor histidine kinase SenX3. | 0.635 |
SEW03051.1 | SEW02985.1 | SAMN05421595_0927 | SAMN05421595_0924 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Protein of unknown function. | 0.658 |
SEW03051.1 | clpS | SAMN05421595_0927 | SAMN05421595_0923 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | ATP-dependent Clp protease adaptor protein ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. | 0.658 |
SEW03051.1 | murI | SAMN05421595_0927 | SAMN05421595_0925 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.977 |
SEW03051.1 | pncA | SAMN05421595_0927 | SAMN05421595_0921 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nicotinamidase/pyrazinamidase. | 0.479 |
SEW03051.1 | pncB | SAMN05421595_0927 | SAMN05421595_0922 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | 0.581 |
SEW03051.1 | rph | SAMN05421595_0927 | SAMN05421595_0926 | XTP/dITP diphosphohydrolase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | RNAse PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.995 |
SEW03505.1 | SEW01805.1 | SAMN05421595_0949 | SAMN05421595_0866 | Hypothetical protein. | Sporulation and spore germination. | 0.451 |