node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SEW04652.1 | panB | SAMN05421595_0998 | SAMN05421595_0996 | Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.918 |
SEW04652.1 | panC | SAMN05421595_0998 | SAMN05421595_0995 | Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.965 |
SEW04652.1 | panD | SAMN05421595_0998 | SAMN05421595_0997 | Predicted oxidoreductase, contains short-chain dehydrogenase (SDR) and DUF2520 domains. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.793 |
SEW12697.1 | panC | SAMN05421595_1388 | SAMN05421595_0995 | Putative TIM-barrel protein, nifR3 family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.677 |
SEW34771.1 | coaBC | SAMN05421595_2347 | SAMN05421595_1516 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.441 |
SEW34771.1 | nadE | SAMN05421595_2347 | SAMN05421595_0465 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.427 |
SEW34771.1 | panB | SAMN05421595_2347 | SAMN05421595_0996 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.936 |
SEW34771.1 | panC | SAMN05421595_2347 | SAMN05421595_0995 | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.923 |
bioA | cmk | SAMN05421595_2582 | SAMN05421595_1322 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Cytidylate kinase. | 0.519 |
bioA | nadE | SAMN05421595_2582 | SAMN05421595_0465 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | NAD+ synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.783 |
bioA | panB | SAMN05421595_2582 | SAMN05421595_0996 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Ketopantoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.462 |
bioA | panC | SAMN05421595_2582 | SAMN05421595_0995 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.706 |
bioA | panD | SAMN05421595_2582 | SAMN05421595_0997 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.542 |
cmk | bioA | SAMN05421595_1322 | SAMN05421595_2582 | Cytidylate kinase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase apoenzyme; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.519 |
cmk | coaBC | SAMN05421595_1322 | SAMN05421595_1516 | Cytidylate kinase. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.471 |
cmk | panC | SAMN05421595_1322 | SAMN05421595_0995 | Cytidylate kinase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.925 |
cmk | panD | SAMN05421595_1322 | SAMN05421595_0997 | Cytidylate kinase. | L-aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.421 |
coaA | coaBC | SAMN05421595_0548 | SAMN05421595_1516 | Pantothenate kinase. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.931 |
coaA | panC | SAMN05421595_0548 | SAMN05421595_0995 | Pantothenate kinase. | Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.919 |
coaBC | SEW34771.1 | SAMN05421595_1516 | SAMN05421595_2347 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Ketopantoate reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. | 0.441 |