STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (464 aa)    
Predicted Functional Partners:
hemB
Porphobilinogen synthase; Belongs to the ALAD family.
 
 
 0.990
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
 0.988
hemC
Hydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.963
SEW32129.1
Uroporphyrinogen III methyltransferase / synthase.
 
 
 0.960
SEW32068.1
Thiol-disulfide isomerase or thioredoxin.
  
  
 0.957
SEW32078.1
Broad specificity phosphatase PhoE.
  
    0.939
SEW40048.1
Non-ribosomal peptide synthase domain TIGR01720/amino acid adenylation domain-containing protein.
  
 0.893
SEW37193.1
Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II.
 
 
 0.862
SEW32057.1
Cytochrome c-type biogenesis protein.
  
  
 0.790
cysG
uroporphyrin-III C-methyltransferase.
 
  
 0.772
Your Current Organism:
Austwickia chelonae
NCBI taxonomy Id: 100225
Other names: A. chelonae, ATCC 51576, CCUG 47447, DSM 44178, Dermatophilus chelonae, JCM 9706, NBRC 105200, strain W16
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